Folate Methylation®

Other Combinations

Brand: Priority One Nutritional Supplements

CapsuleOther CombinationsOn Market
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Net Contents

60 Vegetarian Capsule(s)

Serving Size

2 Vegetarian Capsule(s)

Servings Per Container

30

Supplement Form

Capsule

Bar Code (UPC/SKU)

8 15354 02055 6

Product Version

1068-8550R7

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

12Active Ingredients

12 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

10% Daily Value Coverage

10 ingredients report a %DV; 8 meet or exceed 100% DV.

1Dietary Attributes

Label states: Vegetarian.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Soy

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Vegetarian Capsule(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Thiamine Hydrochloride(Vitamin B1)49 mg4104%
Riboflavin(Riboflavin-5-Phosphate Sodium)50 mg3846%
Niacin(Niacinamide, Vitamin B3)50 mg NE313%
Vitamin B6(Pyridoxal 5-Phosphate)30 mg1765%
Folate((6S)-5-Methyltetrahydrofolic Acid)991 mcg DFE248%
Vitamin B12(Methylcobalamin)1000 mcg41667%
Biotin1000 mcg3333%
Pantothenic Acid(D-Calcium Pantothenate, Vitamin B5)50 mg1000%
Choline3 mg1%
Phosphatidylcholine50 mg
Zinc(Zinc Aspartate, Zinc Oxide, Zinc Rice Chelate)2 mg14%
Trimethylglycine500 mg
Phosphatidylserine(Soybean Extract)100 mg

Not Present

Other Ingredients

Rice ChelateSilicon DioxideSodium SulfateHypromelloseWater, Purified

Target Groups

VegetarianAdult (18 - 50 Years)

Label Claims

All OtherStructure/Function

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: If you are pregnant or breast feeding, consult your physician before using this product.

Precautions re: All Other

Recommendations: Take two (2) capsules daily, or as directed by your physician.

Precautions re: Children

Keep out of reach of children.

Precautions re: Allergies

Contains: Soy (phosphatidylcholine, phosphatidylserine)

Storage

Storage

Keep container tightly closed, store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Contains no preservatives.

Formulation re: Vegetarian/Vegan

Vegetarian formulation

FDA Statements

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

A Dietary Supplement

Other Label Statements

General Statements: All Other Content

Bisphenol-A (BPA) & Phthalate Free

Brand IP Statement(s) re: (c), (TM), (SM)

Priority One Nutritional Supplements Inc since 1988

General Statements: All Other Content

For professional use only.

Brand IP Statement(s) re: (c), (TM), (SM)

Quatrefolic is a registered trademark of Gnosis USA Inc. Protected by U.S. Patent No. 7,947,662

Manufacturer & Distributor

Distributor

Priority One Nutritional Supplements, Inc.

Manufacturer

First Priority Manufacturing, Inc.

2681 Delta Ring Road, Ferndale, WA, 98248

Market Reference

$9.18 – $229.99· 40 listings
  • Priority One Folate Methylation 60 Capsules

    Covenant Health Products4.5(2)
    $24.20
  • Priority Folate — Optifolin+ Active L-Methylfolate | Priority One (30) count

    Priority One Vitamins5.0(1)
    $24.20
  • Priority One Complete One Daily 90 Capsules

    Priority One Vitamins5.0(1)
    $66.00
  • Priority One Daily Foundations Bundle

    Priority One Vitamins
    $130.00
  • Priority One Vitamins - Priority Folate 30 Capsules - Superior Folate Supplementation with Optifolin+ 5MTHF Folate*

    GoSupps.com5.0(1)
    $109.99
  • Methyl- Balance 90 Vegetarian Capsules

    Priority One Vitamins5.0(5)
    $50.60
  • Priority One Women's Formula 240 Capsules

    Priority One Vitamins4.4(5)
    $80.00
  • Priority One Vegetarian Capsules

    Priority One Vitamins4.5(2)
    $65.00

Where to Buy Locally

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  • Farmaenergy

    4.9 (26)

    Vitamin & supplements store

    Via Casilina, 1670/Edif c4, 00133 Roma RM

  • Nutragenix - Integrazione Innovativa

    4.9 (68)

    Vitamin & supplements store

    Largo Messico, 7, 00198 Roma RM

  • Herbalife Nutrition Milano - Distributore Indipendente

    5.0 (48)

    Vitamin & supplements store

    Via Angelo Emo, 19, 20132 Milano MI

  • Vitamina

    4.9 (219)

    E-commerce service

    Via della Fortezza, 21/A, 51100 Pistoia PT

  • Herbalife Nutrition Milano - Distributore Indipendente

    5.0 (1)

    Vitamin & supplements store

    Via Padova, 182, 20132 Milano MI

  • LongLife Nutritional Supplements

    4.5 (19)

    Vitamin & supplements store

    Via 2 Giugno, 60/A1, 20068 Peschiera Borromeo MI

  • Health Store

    Vitamin & supplements store

    57123 Livorno, Province of Livorno

  • Nutripharma Srl

    5.0 (3)

    Natural goods store

    21/G, Via Marlengo, 00124 Roma RM

Research & Studies

  • Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes …

    A Yu, L Feng, X Zhang, Y Wang, Y Wang… - Clinical …, 2019 - search.proquest.com

    … factors of MCI, has become a major priority of global public health. There is no doubt that the … In our discovery group, genome-wide DNA methylation analysis identified that folate was …

    2019155 citations
  • Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges

    H McNulty, M Ward, L Hoey, CF Hughes… - … of the Nutrition Society, 2019 - cambridge.org

    … status of folate, or reported usage of folic acid supplements, with DNA methylation in offspring genes involved in … The health impacts, challenges and research priorities in relation to …

    2019111 citations
  • Scientific opinion on the tolerable upper intake level for folate

    EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2023 - Wiley Online Library

    … conducted to assess evidence on priority adverse health effects of excess intake of folate (including … However, to date, alterations of DNA methylation by high folate intake have not been …

    202335 citations
  • Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health improvement …

    A Caffrey, Y Lamers, MM Murphy… - Nutrition …, 2023 - Wiley Online Library

    … A pyroassay designed to match this region showed good concordance in cord blood samples, and we showed that folic acid drives a similar gain in methylation in maternal blood …

    202325 citations
  • Scientific opinion on the tolerable upper intake level for folate

    EP on Nutrition, N Foods, D Turck, T Bohn… - EFSA …, 2023 - pmc.ncbi.nlm.nih.gov

    … on priority adverse health effects of excess intake of folate (… its intracellular function as a carrier of one‐carbon units (methyl, … methyl groups to methionine for use in methylation reactions. …

    202311 citations
  • Epigenetic genome modifications during pregnancy: the impact of essential nutritional supplements on DNA methylation

    MW Socha, W Flis, M Wartęga - Nutrients, 2024 - mdpi.com

    … modifications by acting via a one-carbon cycle, leading to … methylation. This review article presents the current state of knowledge on the use of folic acid and choline supplementation …

    202440 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-11-22. DSLD Label ID: 277360. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.