Folate Methylation®

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Serving Size: 2 Vegetarian Capsule(s)

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• Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes …

  A Yu, L Feng, X Zhang, Y Wang, Y Wang… - Clinical …, 2019 - search.proquest.com

  … factors of MCI, has become a major priority of global public health. There is no doubt that the … In our discovery group, genome-wide DNA methylation analysis identified that folate was …

  2019155 citations

• Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges

  H McNulty, M Ward, L Hoey, CF Hughes… - … of the Nutrition Society, 2019 - cambridge.org

  … status of folate, or reported usage of folic acid supplements, with DNA methylation in offspring genes involved in … The health impacts, challenges and research priorities in relation to …

  2019111 citations

• Scientific opinion on the tolerable upper intake level for folate

  EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2023 - Wiley Online Library

  … conducted to assess evidence on priority adverse health effects of excess intake of folate (including … However, to date, alterations of DNA methylation by high folate intake have not been …

  202335 citations

• Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health improvement …

  A Caffrey, Y Lamers, MM Murphy… - Nutrition …, 2023 - Wiley Online Library

  … A pyroassay designed to match this region showed good concordance in cord blood samples, and we showed that folic acid drives a similar gain in methylation in maternal blood …

  202325 citations

• Scientific opinion on the tolerable upper intake level for folate

  EP on Nutrition, N Foods, D Turck, T Bohn… - EFSA …, 2023 - pmc.ncbi.nlm.nih.gov

  … on priority adverse health effects of excess intake of folate (… its intracellular function as a carrier of one‐carbon units (methyl, … methyl groups to methionine for use in methylation reactions. …

  202311 citations

• Epigenetic genome modifications during pregnancy: the impact of essential nutritional supplements on DNA methylation

  MW Socha, W Flis, M Wartęga - Nutrients, 2024 - mdpi.com

  … modifications by acting via a one-carbon cycle, leading to … methylation. This review article presents the current state of knowledge on the use of folic acid and choline supplementation …

  202440 citations

• Riboflavin (Vitamin B2) on the Label

  What riboflavin is, how much a typical product provides, and why it can change the color of urine.

  VitaSuppTrack Editorial· Jun 24, 2026

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-09-25. DSLD Label ID: 235735. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.