Osteo Bi-Flex Joint & Energy®
Other CombinationsBrand: Osteo Bi-Flex
Functions
Net Contents
80 Coated Caplet(s)
Serving Size
2 Caplet(s)
Servings Per Container
40
Supplement Form
Other (e.g. tea bag)
Bar Code (UPC/SKU)
0 30768 18870 2
Product Version
52399 00A B52399 MAB
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
15 distinct active ingredients are disclosed in Supplement Facts.
Label includes a proprietary blend, so some individual amounts are not itemized.
10 ingredients report a %DV; 4 meet or exceed 100% DV.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Shellfish
Free From
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 2 Caplet(s) · 1 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Calories | 10 {Calories} | — |
| Total Carbohydrates | 2 Gram(s) | 1% |
| Dietary Fiber | < 1 Gram(s) | 1% |
| Vitamin C(Ascorbic Acid) | 60 mg | 100% |
| Vitamin D(Cholecalciferol, Vitamin D3) | 200 IU | 50% |
| Thiamine(Thiamine Mononitrate, Vitamin B1) | 1 mg | 67% |
| Riboflavin(Vitamin B2) | 1 mg | 59% |
| Vitamin B6(Pyridoxine Hydrochloride) | 2 mg | 100% |
| Vitamin B12(Cyanocobalamin) | 25 mcg | 417% |
| Manganese(Manganese Sulfate) | 2 mg | 100% |
| Sodium | 40 mg | 2% |
| Glucosamine HCl | 1500 mg | — |
| Joint Shield(TM) Proprietary Blend | 1104 mg | — |
| Energy Blend | 0 Not Present | — |
| Chondroitin Sulfate | — | — |
| Collagen(hydrolyzed Gelatin) | — | — |
| Methylsulfonylmethane | — | — |
| Citrus Bioflavonoids | — | — |
| Panax Ginseng Extract | — | — |
| Green Tea extract | — | — |
| White Tea | — | — |
| Eleuthero | — | — |
| Boswellia serrata(Boswellic Acid) | — | — |
| Hyaluronic Acid | — | — |
| 5-LOXIN(R) Advanced AKBA Boswellia serrata Extract | 0 Not Present | — |
| Choline Bitartrate | 50 mg | — |
| Inositol | 50 mg | — |
| Boron(Sodium Tetraborate) | 3 mg | — |
Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
DIRECTIONS FOR ADULT USE: TAKE TWO (2) CAPLETS PER DAY PREFERABLY WITH FOOD.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
CAUTION: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.
Precautions re: All Other
Discontinue use and consult your doctor if any adverse reactions occur.
Precautions re: Children
Not intended for use by persons under the age of 18.
Precautions re: Allergies
Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.
Precautions re: Children
KEEP OUT OF REACH OF CHILDREN.
Precautions re: All Other
TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.
Storage
Storage
STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.
Formulation
Formulation re: Does NOT Contain
Free of Gluten
Formula re: Contains
Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.
Formula re: Contains
It contains 1,500 mg of Glucosamine, a key building block of cartilage.* With the addition of our Joint Shield(TM) Proprietary Blend, which contains Chondroitin, MSM and 5-LOXIN(R) Advanced, this revolutionary Energy Formula helps support energy metabolism and revitalize your joints to keep them jumpin’.*
Formula re: Contains
GLUCOSAMINE CHONDROITIN PLUS JOINT SHIELD(TM)
Formula re: Contains
With 5-LOXIN(R) ADVANCED
FDA Statements
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
DIETARY SUPPLEMENT
Other Label Statements
Seals/Symbols
Proud sponsor of the ARTHRITIS FOUNDATION(R)
Brand IP Statement(s) re: (c), (TM), (SM)
5-LOXIN(R) ADVANCED is a registered trademark of P.L. Thomas - Laila Nutra LLC and is used under license. International Patents Pending.
General: Product/Version Code
52399 00A B52399 MAB
Brand IP Statement(s) re: (c), (TM), (SM)
40 POINTS Osteo Bi-Flex Ambassadors Club(R) For more information visit www.osteobiflex.com
Brand IP Statement(s) re: (c), (TM), (SM)
(C)2012
General Statements: All Other Content
#Based on two human studies with 5-LOXIN(R) Advanced where subjects rated their joint health over time, subjects’ joint health improved within 7 days, and continued to improve throughout the duration of the studies.
General Statements: All Other Content
**52 week Nielsen ScanTrack data ending 8/25/12.
General Statements: All Other Content
Part No. 22-52399
General Statements: All Other Content
HELPS REVITALIZE YOUR JOINTS* KEY BUILDING BLOCK OF CARTILAGE*
General Statements: All Other Content
2 PER DAY
Brand IP Statement(s) re: (c), (TM), (SM)
Join the millions of people who choose Osteo Bi-Flex(R) for their joints every day, and have made it the #1 brand.**
Brand IP Statement(s) re: (c), (TM), (SM)
See Bottom of Package for our Ambassadors Club(R) reward points program.
General Statements: All Other Content
SUPPORT ENERGY METABOLISM
General Statements: All Other Content
#1 DOCTOR & PHARMACIST RECOMMENDED BRAND^
General Statements: All Other Content
As a reminder, discuss the supplements and medications you take with your health care providers.
Seals/Symbols
PROUD SPONSOR of the ARTHRITIS FOUNDATION(R) Rexall Sundown, Inc., the maker of Osteo Bi-Flex(R), is proud to support the Arthritis Foundation's efforts to help people take control of arthritis. For information about arthritis, contact the Foundation at 1-800-568-4045 or www.arthritis.org
General Statements: All Other Content
NEW! SMOOTH WHITE COATING SAME FORMULA
Brand IP Statement(s) re: (c), (TM), (SM)
Osteo Bi-Flex(R) Joint & Energy caplets are a potent combination of highly effective ingredients in Joint Care Science and is the only leading brand containing Joint Shield(TM) with 5-LOXIN(R) Advanced.
Brand IP Statement(s) re: (c), (TM), (SM)
Like calcium supplements can help your bones, Osteo Bi-Flex(R) can help your joints.*
General Statements: All Other Content
The natural aging process can add excessive stress on your joints. Annoying flare-ups can strike at any time. Add Osteo Bi-Flex(R) Joint & Energy to your joint care regimen.
Brand IP Statement(s) re: (c), (TM), (SM)
The only leading brand with 5-LOXIN(R) Advanced.
General Statements: All Other Content
Starts working to improve joint comfort within 7 days.*#
Brand IP Statement(s) re: (c), (TM), (SM)
Osteo Bi-Flex (R) Joint & Energy helps to: >Revitalize Joints* >Promote Mobility* >Support Energy Metabolism*
General Statements: All Other Content
Osteo Bi-Flex(R) is manufactured under the highest standards for product quality, purity and potency.
General Statements: All Other Content
^Based on the results of a GfK Healthcare 2011 survey among physicians who recommend a brand of Glucosamine and Chondroitin or Glucosamine supplements; and the result of a Pharmacy Times Survey among pharmacists who recommend a “bone/joint strengthener” dietary supplement, 2006-2012.
Manufacturer & Distributor
Other
1-888-848-2435
Other
Manufacturer
Rexall Sundown, Inc.
Boca Raton, FL, 33487, USA
Market Reference
Osteo Bi-Flex Triple Strength Tablets
BJ's Wholesale Club4.6(4900)$29.99Osteo Bi-Flex Triple Strength Joint Health Dietary Supplement
Walmart4.4(661)$17.98Osteo Bi Flex Glucosmine HCl Tablets
BJ's Wholesale Club4.8(248)$19.99Osteo Bi-Flex One Per Day Caplets
Walmart4.4(636)$13.28LowestOsteo Bi-Flex Triple Strength + MSM Formula Coated Tablets
CVS Pharmacy4.4(661)$31.49Osteo Bi-Flex Value Pack Coated Tablets
Walmart4.6(4900)$59.96Osteo Bi-Flex Joint Health Triple Strength + Turmeric
CVS Pharmacy4.6(818)$35.49Osteo Bi-Flex Triple Strength Joint Health Supplement
Walmart4.6(4900)$29.98
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
HAWAII DISCOUNT VITAMINS SUPERSTORE - HONOLULU
4.9 (307)Vitamin & supplements store
1600 Kapiolani Blvd Ste 121, Honolulu, HI 96814
GNC
4.1 (75)Vitamin & supplements store
1450 Ala Moana Blvd #1211, Honolulu, HI 96814
The Vitamin Shoppe
4.1 (89)Vitamin & supplements store
1450 Ala Moana Blvd Space 1305, Honolulu, HI 96814
Longs Drugs
3.7 (25)Vitamin & supplements store
2470 S King St, Honolulu, HI 96826
GNC
1.6 (8)Vitamin & supplements store
755 Kapahulu Ave Space 4, Honolulu, HI 96816
GNC
4.0 (13)Vitamin & supplements store
4211 Waialae Ave, Honolulu, HI 96816
The Vitamin Shoppe
4.6 (98)Vitamin & supplements store
98-199 Kamehameha Hwy, Aiea, HI 96701
CVS
4.3 (6)Drug store
3221 Waialae Ave, Honolulu, HI 96816
Research & Studies
Glucosamine and Chondroitin
MJ Cupp, TS Tracy - Dietary Supplements: Toxicology and Clinical …, 2003 - Springer
… Osteo Bi-flex® by Rexall Sundown is the industry leader in glucosamine/chondroitin combination product sales (Anonymous, 1999). Regular strength Osteo Biflex caplets and softgels …
2003Osteo Bi-Flex vs. Move Free (I Tried Both): Who Wins In 2026?
RK Range, RUSG Guide, RUHB Guide - blog.revgear.com
… Osteo Bi-Flex is one of the more effective joint supplements on the market. Move Free has been the least helpful of the dozen I have tried, so Osteo Bi-Flex … joint pain, and Osteo Bi-Flex …
Relief Factor vs. Osteo Bi-Flex (I Tried Both): Who Wins In 2026?
RK Range, RUSG Guide, RUHB Guide - blog.revgear.com
… As with all supplements in this segment, Osteo Bi-Flex is aimed mainly at customers in the later stages of their lives. People who want to continue doing what they love, be active, and …
A Pharmacist's Guide to Osteo Bi-Flex® Joint Health Dietary Supplements
AIINDJ CARE - clinical trials, 2024
20241 citationsA systemic review of treatment of rheumatoid arthritis using herbal plants
S Dhruvi, K Honey, P Rahul - International Journal of Scientific …, 2025 - ijsrtjournal.com
… system whose major role is to protect the health by attacking foreign bacteria and viruses are mistakenly, attacking the joints resulting in thickened synovium, pannus formation & …
20252 citationsAging and herbal interventions: mechanistic insights and therapeutic potential
D Suvedi, A Kumar, S Kalia, A Kumar… - Journal of Cosmetic …, 2025 - Wiley Online Library
… jointEase Chondroitin, MSM, and glucosamine Move free, osteo bi-flex Promotes cartilage growth and reduces inflammation Joint mobility and cartilage support Tablets [145], [146], [147…
202514 citations
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Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-02-26. DSLD Label ID: 30801. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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