Osteo Bi-Flex Joint & Energy®

Other Combinations

Brand: Osteo Bi-Flex

Other (e.g. tea bag)Other CombinationsOn Market
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Net Contents

80 Coated Caplet(s)

Serving Size

2 Caplet(s)

Servings Per Container

40

Supplement Form

Other (e.g. tea bag)

Bar Code (UPC/SKU)

0 30768 18870 2

Product Version

52399 00A B52399 MAB

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

15Active Ingredients

15 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

10% Daily Value Coverage

10 ingredients report a %DV; 4 meet or exceed 100% DV.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Shellfish

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Caplet(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Calories10 {Calories}
Total Carbohydrates2 Gram(s)1%
Dietary Fiber< 1 Gram(s)1%
Vitamin C(Ascorbic Acid)60 mg100%
Vitamin D(Cholecalciferol, Vitamin D3)200 IU50%
Thiamine(Thiamine Mononitrate, Vitamin B1)1 mg67%
Riboflavin(Vitamin B2)1 mg59%
Vitamin B6(Pyridoxine Hydrochloride)2 mg100%
Vitamin B12(Cyanocobalamin)25 mcg417%
Manganese(Manganese Sulfate)2 mg100%
Sodium40 mg2%
Glucosamine HCl1500 mg
Joint Shield(TM) Proprietary Blend1104 mg
Energy Blend0 Not Present
Chondroitin Sulfate
Collagen(hydrolyzed Gelatin)
Methylsulfonylmethane
Citrus Bioflavonoids
Panax Ginseng Extract
Green Tea extract
White Tea
Eleuthero
Boswellia serrata(Boswellic Acid)
Hyaluronic Acid
5-LOXIN(R) Advanced AKBA Boswellia serrata Extract0 Not Present
Choline Bitartrate50 mg
Inositol50 mg
Boron(Sodium Tetraborate)3 mg

Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients

CelluloseCrospovidoneContains Less Than 2% of

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

DIRECTIONS FOR ADULT USE: TAKE TWO (2) CAPLETS PER DAY PREFERABLY WITH FOOD.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

CAUTION: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Precautions re: All Other

Discontinue use and consult your doctor if any adverse reactions occur.

Precautions re: Children

Not intended for use by persons under the age of 18.

Precautions re: Allergies

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Precautions re: Children

KEEP OUT OF REACH OF CHILDREN.

Precautions re: All Other

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

Storage

Storage

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

Formulation

Formulation re: Does NOT Contain

Free of Gluten

Formula re: Contains

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Formula re: Contains

It contains 1,500 mg of Glucosamine, a key building block of cartilage.* With the addition of our Joint Shield(TM) Proprietary Blend, which contains Chondroitin, MSM and 5-LOXIN(R) Advanced, this revolutionary Energy Formula helps support energy metabolism and revitalize your joints to keep them jumpin’.*

Formula re: Contains

GLUCOSAMINE CHONDROITIN PLUS JOINT SHIELD(TM)

Formula re: Contains

With 5-LOXIN(R) ADVANCED

FDA Statements

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Other Label Statements

Seals/Symbols

Proud sponsor of the ARTHRITIS FOUNDATION(R)

Brand IP Statement(s) re: (c), (TM), (SM)

5-LOXIN(R) ADVANCED is a registered trademark of P.L. Thomas - Laila Nutra LLC and is used under license. International Patents Pending.

General: Product/Version Code

52399 00A B52399 MAB

Brand IP Statement(s) re: (c), (TM), (SM)

40 POINTS Osteo Bi-Flex Ambassadors Club(R) For more information visit www.osteobiflex.com

Brand IP Statement(s) re: (c), (TM), (SM)

(C)2012

General Statements: All Other Content

#Based on two human studies with 5-LOXIN(R) Advanced where subjects rated their joint health over time, subjects’ joint health improved within 7 days, and continued to improve throughout the duration of the studies.

General Statements: All Other Content

**52 week Nielsen ScanTrack data ending 8/25/12.

General Statements: All Other Content

Part No. 22-52399

General Statements: All Other Content

HELPS REVITALIZE YOUR JOINTS* KEY BUILDING BLOCK OF CARTILAGE*

General Statements: All Other Content

2 PER DAY

Brand IP Statement(s) re: (c), (TM), (SM)

Join the millions of people who choose Osteo Bi-Flex(R) for their joints every day, and have made it the #1 brand.**

Brand IP Statement(s) re: (c), (TM), (SM)

See Bottom of Package for our Ambassadors Club(R) reward points program.

General Statements: All Other Content

SUPPORT ENERGY METABOLISM

General Statements: All Other Content

#1 DOCTOR & PHARMACIST RECOMMENDED BRAND^

General Statements: All Other Content

As a reminder, discuss the supplements and medications you take with your health care providers.

Seals/Symbols

PROUD SPONSOR of the ARTHRITIS FOUNDATION(R) Rexall Sundown, Inc., the maker of Osteo Bi-Flex(R), is proud to support the Arthritis Foundation's efforts to help people take control of arthritis. For information about arthritis, contact the Foundation at 1-800-568-4045 or www.arthritis.org

General Statements: All Other Content

NEW! SMOOTH WHITE COATING SAME FORMULA

Brand IP Statement(s) re: (c), (TM), (SM)

Osteo Bi-Flex(R) Joint & Energy caplets are a potent combination of highly effective ingredients in Joint Care Science and is the only leading brand containing Joint Shield(TM) with 5-LOXIN(R) Advanced.

Brand IP Statement(s) re: (c), (TM), (SM)

Like calcium supplements can help your bones, Osteo Bi-Flex(R) can help your joints.*

General Statements: All Other Content

The natural aging process can add excessive stress on your joints. Annoying flare-ups can strike at any time. Add Osteo Bi-Flex(R) Joint & Energy to your joint care regimen.

Brand IP Statement(s) re: (c), (TM), (SM)

The only leading brand with 5-LOXIN(R) Advanced.

General Statements: All Other Content

Starts working to improve joint comfort within 7 days.*#

Brand IP Statement(s) re: (c), (TM), (SM)

Osteo Bi-Flex (R) Joint & Energy helps to: >Revitalize Joints* >Promote Mobility* >Support Energy Metabolism*

General Statements: All Other Content

Osteo Bi-Flex(R) is manufactured under the highest standards for product quality, purity and potency.

General Statements: All Other Content

^Based on the results of a GfK Healthcare 2011 survey among physicians who recommend a brand of Glucosamine and Chondroitin or Glucosamine supplements; and the result of a Pharmacy Times Survey among pharmacists who recommend a “bone/joint strengthener” dietary supplement, 2006-2012.

Manufacturer & Distributor

Other

1-888-848-2435

Other

Manufacturer

Rexall Sundown, Inc.

Boca Raton, FL, 33487, USA

Market Reference

$13.28 – $100.26· 40 listings
  • Osteo Bi-Flex Triple Strength Tablets

    BJ's Wholesale Club4.6(4900)
    $29.99
  • Osteo Bi-Flex Triple Strength Joint Health Dietary Supplement

    Walmart4.4(661)
    $17.98
  • Osteo Bi Flex Glucosmine HCl Tablets

    BJ's Wholesale Club4.8(248)
    $19.99
  • Osteo Bi-Flex One Per Day Caplets

    Walmart4.4(636)
    $13.28Lowest
  • Osteo Bi-Flex Triple Strength + MSM Formula Coated Tablets

    CVS Pharmacy4.4(661)
    $31.49
  • Osteo Bi-Flex Value Pack Coated Tablets

    Walmart4.6(4900)
    $59.96
  • Osteo Bi-Flex Joint Health Triple Strength + Turmeric

    CVS Pharmacy4.6(818)
    $35.49
  • Osteo Bi-Flex Triple Strength Joint Health Supplement

    Walmart4.6(4900)
    $29.98

Where to Buy Locally

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Research & Studies

  • Glucosamine and Chondroitin

    MJ Cupp, TS Tracy - Dietary Supplements: Toxicology and Clinical …, 2003 - Springer

    … Osteo Bi-flex® by Rexall Sundown is the industry leader in glucosamine/chondroitin combination product sales (Anonymous, 1999). Regular strength Osteo Biflex caplets and softgels …

    2003
  • Osteo Bi-Flex vs. Move Free (I Tried Both): Who Wins In 2026?

    RK Range, RUSG Guide, RUHB Guide - blog.revgear.com

    … Osteo Bi-Flex is one of the more effective joint supplements on the market. Move Free has been the least helpful of the dozen I have tried, so Osteo Bi-Flex … joint pain, and Osteo Bi-Flex …

  • Relief Factor vs. Osteo Bi-Flex (I Tried Both): Who Wins In 2026?

    RK Range, RUSG Guide, RUHB Guide - blog.revgear.com

    … As with all supplements in this segment, Osteo Bi-Flex is aimed mainly at customers in the later stages of their lives. People who want to continue doing what they love, be active, and …

  • A Pharmacist's Guide to Osteo Bi-Flex® Joint Health Dietary Supplements

    AIINDJ CARE - clinical trials, 2024

    20241 citations
  • A systemic review of treatment of rheumatoid arthritis using herbal plants

    S Dhruvi, K Honey, P Rahul - International Journal of Scientific …, 2025 - ijsrtjournal.com

    … system whose major role is to protect the health by attacking foreign bacteria and viruses are mistakenly, attacking the joints resulting in thickened synovium, pannus formation & …

    20252 citations
  • Aging and herbal interventions: mechanistic insights and therapeutic potential

    D Suvedi, A Kumar, S Kalia, A Kumar… - Journal of Cosmetic …, 2025 - Wiley Online Library

    … jointEase Chondroitin, MSM, and glucosamine Move free, osteo bi-flex Promotes cartilage growth and reduces inflammation Joint mobility and cartilage support Tablets [145], [146], [147…

    202514 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-02-26. DSLD Label ID: 30801. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.