System-Six®

Other Combinations

Brand: Irwin Naturals

Softgel CapsuleOther CombinationsOn Market
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Net Contents

60 Liquid Softgel(s)

Serving Size

3 Liquid Softgel(s)

Servings Per Container

20

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 10363 59875 4

Product Version

9754-LAB-IN039875-V3-06/21

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

30Active Ingredients

30 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

13% Daily Value Coverage

13 ingredients report a %DV; 3 meet or exceed 100% DV.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Fish
  • Soy

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 3 Liquid Softgel(s) · 2 per day

IngredientAmount Per Serving% Daily Value
Calories25 Calorie(s)
Total Fat1.5 Gram(s)2%
Cholesterol5 mg2%
Total Carbohydrates2 Gram(s)1%
Protein2 Gram(s)
Vitamin C(Ascorbic Acid)8 mg9%
Vitamin E(D-Alpha-Tocopherol)4.5 mg30%
Thiamine(Thiamine Hydrochloride)0.5 mg42%
Riboflavin0.5 mg38%
Niacin(Niacinamide)7 mg44%
Vitamin B12(Cyanocobalamin)7 mcg292%
Pantothenic Acid(D-Calcium Pantothenate)15 mg300%
Choline(Choline Bitartrate)20 mg3%
Selenium(Selenium Aspartate)17 mcg31%
Chromium(Chromium Picolinate)100 mcg286%
Fish Oil(Anchovy, Sardine)1800 mg
Eicosapentaenoic Acid324 mg
Docosahexaenoic Acid216 mg
Garcinia fruit rind extract335 mg
White Tea Leaf Extract300 mg
Epigallocatechin Gallate150 mg
Green Tea Leaf Extract150 mg
Caffeine75 mg
Schisandra Fruit Extract(Schisandra chinensis fruit extract)100 mg
L-Carnitine(L-Carnitine Fumarate)80 mg
L-Theanine50 mg
L-Tyrosine40 mg
Cayenne, Powder20 mg
Ginger, Powder20 mg
Guarana (Paullinia cupana) powder20 mg
Inositol20 mg
Mate (Yerba Mate) extract20 mg
Spirulina, Powder20 mg
BioPerine Complex3 mg
BioPerine(Black Pepper Fruit Extract)
Ginger Rhizome Extract(Gingerols)

% Daily Value based on a 2,000 calorie diet

Amino Acid Profile

3 amino acids detected on the label. Bars show the disclosed amount per serving; total mapped amino acids ≈ 170 mg.

Essential amino acidNon-essential

Other Ingredients

GelatinWater, PurifiedGlycerinBeeswaxSunflower LecithinRice FlourAnnattoMaltodextrinTitanium DioxideTurmericSoybean OilSt. John's BreadDicalcium PhosphateSilicon DioxideSodium Copper Chlorophyllin

Target Groups

Adult (18 - 50 Years)Women (not pregnant or lactating)

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: (Adult) As an addition to your reduced calorie diet and exercise plan, take three (3) Liquid Soft-Gels in the morning and three (3) Liquid Soft-Gels in the afternoon with meals and a full glass (8oz) of water. If caffeine keeps you up at night, do not take this product in the evening since it contains caffeine.

Warnings & Precautions

Precautions re: All Other

Usage Warnings: Do not use if safety seal is broken. This product contains an ingredient that may affect blood sugar. This product contains niacin and may cause a temporary warming and tingling sensation.

Precautions re: Pregnant or Nursing or Prescription Medications

Check with your doctor before using this product if you are using medication or have any medical conditions, including, but not limited to, heart disease, high blood pressure, an iron deficiency, a liver disorder or develop symptoms of liver trouble (such as abdominal pain, dark urine or jaundice).

Precautions re: All Other

It is recommended to limit additional caffeine intake while taking this product.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if you may become pregnant, are pregnant or nursing.

Precautions re: All Other

Do not exceed recommended daily intake.

Precautions re: Children

Not intended for use by persons under 18. Keep out of reach of children.

Precautions re: All Other

Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Precautions re: All Other

If caffeine keeps you up at night, do not take this product in the evening since it contains caffeine.

Precautions re: Allergies

Contains: Fish (anchovy, sardine), Soy

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Other

System-Six is a specialized formula that delivers six support systems to assist with your weight loss goals.

Formula re: Contains

One: Thermogenesis - A combination of Green and White Tea extracts supply powerful nutrients to enhance thermogenesis (heat production) and help burn calories. Two: Energy - Natural caffeine plus the botanicals Yerba Mate, Guarana and Spirulina help you feel energized. Three: Mood - L - Theanine is included in this formula to support mood. Four: Metabolism - A combination of B vitamins help convert food into energy and assist in the breakdowns of carbs, fats and proteins. Five: Carbohydrate Support - Chromium supports the breakdown to carbohydrates into glucose and helps to maintain healthy blood sugar levels already within a normal range. Six: Antioxidants - Vitamins C and E plus other nutrients with antioxidant activity help to protect cell health and offer nutritional support for the body.

Formulation re: Other

When combined with a reduced calorie diet and exercise plan, System-Six delivers powerful weight loss support to help you meet your goals.

Formulation re: Other

What makes us different: Liquid Soft-Gels - The nutrients in these easy-to-swallow Liquid Soft-Gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft-Gels provide an optimum delivery system.

Formulation re: Other

Quality Assurance - Irwin Naturals is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency.

Formula re: Contains

Patented BioPerine - Our special BioPerine Complex enhances the bioavailability, absorption and potency of many nutrients.

Formulation re: Other

Powerful Weight Loss Support Metabolism Boosters & Carb Metabolizer Complete Six-In-One Formula for Enhanced Metabolism, plus Mood & Energy Support

Formulation re: Does NOT Contain

No preservatives added.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Seals/Symbols

Pass Quality Tested Guaranteed

General Statements: All Other Content

Global Responsibility - Over the years we have donated to organizations that support the environment and the health of our children.

General Statements: All Other Content

Diet & Exercise Plan available online at: www.IrwinNaturals.com/deplan 100+ Highly Specialized Products: www.IrwinNaturals.com

Brand IP Statement(s) re: (c), (TM), (SM)

BioPerine is a registered trademark of Sabinsa Corporation.

General Statements: All Other Content

Questions: Contact Consumer Affairs 1-800-297-3273 Weekdays 8:00 AM to 5:00 PM (PST) Questions@IrwinNaturals.com Full disclosure ingredient panel

Manufacturer & Distributor

Manufacturer

Irwin Naturals

5310 Beethoven Street, Los Angeles, CA, 90066

1-800-297-3273

Questions@IrwinNaturals.com

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Research & Studies

  • Green biosynthesis of DHA-phospholipids in tailor-made supersaturated DHA aqueous solution and catalytic mechanism study

    T Zhang, J Wang, Y Zhao, Z Wang, D Hu, Y Liu… - Food chemistry, 2024 - Elsevier

    Docosahexaenoic acid-phospholipids (DHA-PLs) were prepared via lipase-mediated transesterification of DHA donor and phosphatidylcholine (PC) in a purely aqueous solution. Pre-…

    202414 citations
  • A novel digital biomarker of sarcopenia in frail elderly: New combination of gait parameters under dual-task walking

    Z Zhou, Y Huang, J Wang, H Su, H Tang… - Frontiers in Aging …, 2023 - frontiersin.org

    … In this study, the sociodemographic and medical characteristics of subjects from the two groups showed that frail patients with sarcopenia were leaner and presented with a higher …

    202320 citations
  • Healing the hardware of the soul: How making the brain-soul connection can optimize your life, love, and spiritual growth

    D Amen - 2008 - books.google.com

    … ORU was an amazing place to attend medical school. We were taught solid medical science in an atmosphere of love, compassion, and prayer. It was different from every other medical …

    200883 citations
  • Exogenous Agents as Drivers of Neurodegeneration: From Pharmaceuticals and Natural Toxins to Nanoparticles—A One Health Perspective

    E Gözüperk, T Bakırel - Journal of Istanbul Veterinary Sciences, 2026 - dergipark.org.tr

    … , and multiple sclerosis represent a growing global health issue. Although addressed in a … the one health concept, as well as studies involving pet and experimental animal models. …

    2026
  • Breast cancer primary prevention and diet: an umbrella review

    A Buja, M Pierbon, L Lago, G Grotto… - … research and public health, 2020 - mdpi.com

    … literature to produce guidelines and health policies promoting healthy eating styles to prevent … choices can affect health and the risk of cancer. Overall, adhering to a healthy eating style …

    2020150 citations
  • Banned and discouraged-use ingredients found in weight loss supplements

    S Eichner, M Maguire, LA Shea, MG Fete - Journal of the American …, 2016 - Elsevier

    … health by using these supplements to lose weight, but in reality they could be disturbing an already serious health … and health care providers that there are dietary supplements available …

    201629 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-07-18. DSLD Label ID: 292134. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.