Active Methylated B Complex®

Other Combinations

Brand: Approved Science

CapsuleOther CombinationsOn Market
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Net Contents

60 Capsule(s)

Serving Size

2 Capsule(s)

Servings Per Container

30

Supplement Form

Capsule

Bar Code (UPC/SKU)

X004KWQSMJ

Product Version

v1.00

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

10Active Ingredients

10 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

9% Daily Value Coverage

9 ingredients report a %DV; 8 meet or exceed 100% DV.

2Dietary Attributes

Label states: Vegan, Vegetarian.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 2 Capsule(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Vitamin B1(Thiamine Hydrochloride)50 mg4166%
Vitamin B2(Riboflavin 5-Phosphate)10 mg769%
Vitamin B3(Niacinamide)25 mg NE156%
Vitamin B6(Pyridoxal 5-Phosphate)10 mg588%
Quatrefolic(Folate)680 mg DFE170%
BalaSci Vitamin B12 Complex(Adenosylcobalamin, Methylcobalamin)500 mcg20833%
Vitamin B7(Biotin)500 mcg1666%
Vitamin B5(Pantothenic Acid)50 mg1000%
Choline(Choline Bitartrate)150 mg27%
Betaine(Trimethylglycine)250 mg

% Daily Value (DV) based on a 2000 calorie diet

Other Ingredients

Cellulose

Target Groups

VeganVegetarianAdult (18 - 50 Years)Dairy Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two capsules daily, (one in the morning and one in the afternoon) with meals and an 8oz. glass of water.

Warnings & Precautions

Precautions re: All Other

Caution: Do not exceed recommended dose.

Precautions re: Pregnant or Nursing or Prescription Medications

Pregnant women or nursing mothers, children under 18, individuals with a known medical condition, and those taking anticoagulant or antiplatelet medications, should consult with a physician before taking this or any other dietary supplement.

Precautions re: Children

Pregnant women or nursing mothers, children under 18, individuals with a known medical condition, and those taking anticoagulant or antiplatelet medications, should consult with a physician before taking this or any other dietary supplement. Keep out of reach of children.

Precautions re: All Other

Do not use if safety seal is damaged or missing.

Storage

Storage

Store at room temperature.

Formulation

Formulation re: Other

Manufactured in the USA with global ingredients according to current Good Manufacturing Practice (cGMP) and conforms to the tested ingredient grade, strength and purity of industry quality standards.

Formulation re: Does NOT Contain

GMO Free Made with ingredients

Formulation re: Vegetarian/Vegan

Vegan friendly

Formula re: Contains

Active Methylated B Complex with patented methylfolate with Quatrefolic high absorption folate

Formulation re: Other

Premium grade High Potency Trusted Fast Natural Formula Optimal strength GMP Certified

Formulation re: Vegetarian/Vegan

100% vegan friendly

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

Seals/Symbols

Vegan friendly Made in USA No animal testing GMP Good manufacturing practice Quality products

Brand IP Statement(s) re: (c), (TM), (SM)

Active Methylated B Complex with patented methylfolate

Manufacturer & Distributor

Distributor

Approved Science

New York, NY, 10003

888-307-4790

support@approvedscience.com

Market Reference

$0.11 – $129.00· 40 listings
  • Approved Science Methylated B-Complex (1 Month Supply)

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  • CellCore Methyl-B Complex 60 Capsules

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    $27.95
  • Methylated B Complex for Energy & Health Support 120 Capsules

    Dr Aziz Pharmacy
    $18.81
  • Methylated B-Complex 60ct

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    $29.99
  • Active Methyl B-12 Folate Lozenges

    Core Med Science4.8(19)
    $19.99
  • Methyl Active B Bioavailable Folate B12 System Support

    Pure TheraPro Rx4.8(13)
    $28.97
  • Nutricost Methylated Vitamin B Complex

    Walmart - eSupplements, llc4.6(71)
    $15.95

Where to Buy Locally

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Research & Studies

  • The effect of methylated vitamin B complex on depressive and anxiety symptoms and quality of life in adults with depression

    JE Lewis, E Tiozzo, AB Melillo… - International …, 2013 - Wiley Online Library

    … patients receiving FDA-approved antidepressants experience … process of a vitamin B complex supplement’s efficacy and … Stress B offers utility for improving the overall mental health …

    201383 citations
  • Simplifying the B complex: how vitamins B6 and B9 modulate one carbon metabolism in cancer and beyond

    CN Franco, LJ Seabrook, ST Nguyen, JT Leonard… - Metabolites, 2022 - mdpi.com

    … in health and dysregulation in disease (Figure 1). Folate enters the one carbon pathway through active forms of tetrahydrofolate (THF) that carry methyl-… analog that was approved by the …

    202246 citations
  • Methylation Plus

    WN Range - vitalitywellnessclinic.com

    … health, prenatal development, and the conversion of homocysteine back to methionine. In its active form, folic acid serves as a donor of methyl … of supplementation to support healthy …

  • Randomized, placebo-controlled trial of methyl B12 for children with autism

    …, SJ James, F Widjaja, B Lawton… - Journal of child and …, 2016 - journals.sagepub.com

    … The study was conducted with an approved Investigational … , was compared between the active and placebo groups at the … in this study to help advance scientific research in autism. A …

    2016171 citations
  • The B Vitamins and Cognitive Health: Methylation, Mitochondrial Function, and Neuronal Integrity

    K Goyal, R Dahiya, M Abubakar, M Bishnoi… - Vitamins and … - api.taylorfrancis.com

    … (active B12) as a prosthetic group. An alternative … , such as methyl folate or methylcobalamin dietary supplements [130]. With … related B vitamins on brain health throughout life: scientific …

  • Vitamin B supplementation and nutritional intake of methyl donors in patients with chronic kidney disease: a critical review of the impact on epigenetic …

    M Cappuccilli, C Bergamini, FA Giacomelli, G Cianciolo… - Nutrients, 2020 - mdpi.com

    … methylation and DNA methyltransferase (DNMT) expression, comparing 20 patients under chronic hemodialysis with 20 healthy … and avoids the active principle degradation. Therefore, …

    202053 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-09-25. DSLD Label ID: 339385. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.