Active Methylated B Complex

Other Combinations

Brand: Approved Science

CapsuleOn Market
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Net Contents

60 Capsule(s)

Serving Size

2 Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

X004KWQSMJ

Product Version

Not specified

Suggested Use

Directions: As a dietary supplement; take two capsules daily; (one in the morning and one in the afternoon) with meals and an 8oz. glass of water.

Market Reference

$4.94 – $163.20· 40 listings
  • Approved Science Methylated B-Complex (1 Month Supply)

    Approved Science
    $49.95
  • Just Ingredients Methylated B Complex Capsules

    Target4.8(1200)
    $33.99
  • Life Extension BioActive Complete B Complex

    Walmart4.8(37000)
    $9.00
  • Methyl Active B Bioavailable Folate B12 System Support

    Pure TheraPro Rx4.8(13)
    $28.97
  • Objective Nutrients ThiActive B Methylated B-Complex

    Objective Nutrients4.0(1)
    $29.99
  • methylation B complex+ methylated B vitamins for MTHFR gene variant*

    mindbodygreen4.1(37)
    $59.00
  • MegaFood Balanced B Complex

    Whole Foods Market4.8(2000)
    $26.76
  • NATURE MADE Super B-Complex Tablets

    Walgreens.com4.8(2800)
    $16.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • GNC

    3.1 (65)

    Vitamin & supplements store

    10655 Big Bend Rd Ste 208, Riverview, FL 33579

  • Southern Nutrition

    5.0 (214)

    Vitamin & supplements store

    10458 Stelling Dr, Riverview, FL 33578

  • Nutrishop Valrico

    4.9 (151)

    Vitamin & supplements store

    3240 Lithia Pinecrest Rd #103, Valrico, FL 33596

  • Southern Nutrition

    5.0 (1403)

    Vitamin & supplements store

    2940 Providence Lakes Blvd, Brandon, FL 33511

  • The Vitamin Shoppe

    4.4 (217)

    Vitamin & supplements store

    Plaza at, 101 Brandon Town Center Dr, Brandon, FL 33511

  • The B12 Store - Brandon

    5.0 (102)

    Vitamin & supplements store

    873 Brandon Town Center Mall, Brandon, FL 33511

  • Foundation Supplements

    4.8 (37)

    Vitamin & supplements store

    3409 W Bay to Bay Blvd, Tampa, FL 33629

  • GNC

    3.5 (34)

    Vitamin & supplements store

    3830 Sun City Center Blvd Ste 101, Sun City Center, FL 33573

Research & Studies

  • The effect of methylated vitamin B complex on depressive and anxiety symptoms and quality of life in adults with depression

    JE Lewis, E Tiozzo, AB Melillo… - International …, 2013 - Wiley Online Library

    … patients receiving FDA-approved antidepressants experience … process of a vitamin B complex supplement’s efficacy and … Stress B offers utility for improving the overall mental health …

    201383 citations
  • Simplifying the B complex: how vitamins B6 and B9 modulate one carbon metabolism in cancer and beyond

    CN Franco, LJ Seabrook, ST Nguyen, JT Leonard… - Metabolites, 2022 - mdpi.com

    … in health and dysregulation in disease (Figure 1). Folate enters the one carbon pathway through active forms of tetrahydrofolate (THF) that carry methyl-… analog that was approved by the …

    202245 citations
  • Methylation Plus

    WN Range - vitalitywellnessclinic.com

    … health, prenatal development, and the conversion of homocysteine back to methionine. In its active form, folic acid serves as a donor of methyl … of supplementation to support healthy …

  • Randomized, placebo-controlled trial of methyl B12 for children with autism

    …, SJ James, F Widjaja, B Lawton… - Journal of child and …, 2016 - journals.sagepub.com

    … The study was conducted with an approved Investigational … , was compared between the active and placebo groups at the … in this study to help advance scientific research in autism. A …

    2016168 citations
  • The B Vitamins and Cognitive Health: Methylation, Mitochondrial Function, and Neuronal Integrity

    K Goyal, R Dahiya, M Abubakar, M Bishnoi… - Vitamins and … - api.taylorfrancis.com

    … (active B12) as a prosthetic group. An alternative … , such as methyl folate or methylcobalamin dietary supplements [130]. With … related B vitamins on brain health throughout life: scientific …

  • Vitamin B supplementation and nutritional intake of methyl donors in patients with chronic kidney disease: a critical review of the impact on epigenetic …

    M Cappuccilli, C Bergamini, FA Giacomelli, G Cianciolo… - Nutrients, 2020 - mdpi.com

    … methylation and DNA methyltransferase (DNMT) expression, comparing 20 patients under chronic hemodialysis with 20 healthy … and avoids the active principle degradation. Therefore, …

    202053 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-09-25. DSLD Label ID: 339385. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.