SAM-e 200 mg®
Non-Nutrient / Non-BotanicalBrand: Wonder Laboratories
Functions
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
2 Tablet(s)
Servings Per Container
15
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 99528 22230 8
Product Version
Rev. #02
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Egg
- Fish
- Shellfish
- Tree Nuts
- Peanut
- Soy
Free From
- Wheat
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 2 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosylmethionine | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: For adults, we recommend taking two (2) tablets daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal.
Warnings & Precautions
Precautions re: All Other
Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Precautions re: Pregnant or Nursing or Prescription Medications
Caution: You should consult your physician before using SAM-e if you are taking MAO inhibitors. Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.
Precautions re: Children
Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.
Precautions re: All Other
Individuals affected by bipolar (manic) depression should not take this product. Discontinue use and consult your physician if gastrointestinal discomfort occurs.
Precautions re: Children
Keep out of reach of children.
Storage
Storage
Keep tightly closed. Store at room temperature: 59 degrees – 86 degrees F (15 degrees – 30 degrees C).
Formulation
Formulation re: Other
All living things contain SAM-e (S-adenosylmethionine). The body makes SAM-e from the amino acid methionine. However, you may not be able to obtain sufficient methionine levels simply by ingesting food. In addition, because of age or other factors, levels of SAM-e can fluctuate or decline. Supplementation with SAM-e is the easiest way to increase intake. SAM-e is involved in over 36 biochemical reactions involving enzymatic transmethylation. The methylation process is the mechanism by which the body rids itself of potentially damaging compounds, synthesizes neurotransmitters, makes components of cartilage, regulates enzyme activity within the cell and maintains the flexibility of cell membranes. Science has been looking into this remarkable supplement and time after time clinical studies have drawn the same conclusions. SAM-e promotes healthy joint function and comfort, boosts mood and emotional well-being.
Formulation re: Other
A note about our enteric coating: SAM-e is enterically coated so that you receive optimal absorption. The enteric coating ensures that the breakdown of SAM-e occurs in the small intestine. Clinical trials indicate that absorption is more efficient in the small intestine rather than in the stomach. In addition, the enteric coating is designed to protect SAM-e from moisture. The lack of an enteric coating should not be harmful to the stomach, and there have been no reported cases to this effect. However, the enteric coating serves as a protective barrier so that SAM-e can be absorbed where it can provide you with the greatest benefits.
Formula re: Contains
S-adenosylmethionine
Formulation re: Other
Promotes healthy joint function and comfort Boosts mood and emotional well-being Supports healthy liver function
Formulation re: Does NOT Contain
Gluten free
Formulation re: Other
Manufactured in an FDA Registered Facility using Good Manufacturing Practices (GMPs).
Formulation re: Vegetarian/Vegan
Suitable for vegetarians/vegans
Formulation re: Does NOT Contain
Contains no wheat, soy, dairy, egg, fish/shellfish, peanuts/tree nuts.
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
SAM-e is a revolutionary supplement. Because of its popularity and use, it has received widespread exposure in the press. Information has appeared in newspapers, magazines, on the internet, or simply through word of mouth. Whether you're a first time SAM-e user or have been a fan for years, you probably have some questions. Please see enclosed insert for more information.
General Statements: All Other Content
Reorder #2222
General Statements: All Other Content
Made in USA
General Statements: All Other Content
SAM-e discovered in Italy in 1952 and has been one of Europe's best kept secret for years. Through extensive testing, SAM-e has been found to be a safe, nontoxic supplement for nearly everyone in levels of up to 1,600 mg per day.
Manufacturer & Distributor
Distributor
Wonder Laboratories
115 S.C.T. Ct., White House, TN, 37188
Market Reference
Nature's Craft SAM-e 200 mg Capsules
Target4.8(269)$20.15
Nature Made SAM-e Complete 400 mg
Walmart - Health4life4.5(45)$46.12
Sam-e 200 200mg
Pure Prescriptions4.6(438)$55.99
SAM-e 200 mg 30 Tablets
LifeSource Vitamins4.5(2)$29.99
SAM-E 200 mg 60 Capsules
Physicians Preference Vitamins$84.50
SAM-E 200mg Tablets (30 Tabs)
McGuff Medical Products$22.75
SAMe 200mg 60 Tablets
Walmart - BESTVITE INC4.7(159)$24.99
NOW Foods SAMe 200 mg 60 Veg Capsules
Dr. Judy Morgan's Naturally Healthy Pets4.6(14)$39.99
Where to Buy Locally
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SFI Health™ | for Clinicians and their Patients
4.2 (5)Manufacturer
795 Trademark Dr, Reno, NV 89521
Research & Studies
S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… depressive symptoms were seen ranging from 200 mg to 3200 mg. Many studies started at … doses starting at 200 mg to 800 mg for mild–moderate depression and 800 mg daily in one to …
202410 citationsEvidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
GI Papakostas - Journal of Clinical Psychiatry, 2009 - psychiatrist.com
… 200 mg/d of intravenous SAM-e to be equivalent to placebo in antidepressant effect among patients with MDD overall, a significant treatment effect in favor of SAM-e … for laboratory use) …
2009178 citationsOverview of Complementary, Alternative, and Integrative Approaches
RA OWENS - … and Alternative Approaches Across the Life Span, 2022 - books.google.com
… SAM-e may increase the production of serotonin and dopamine or increase the number or receptivity of receptors. Lower levels of SAM-e … Dosage is recommended to start at 200 mg …
20221 citations… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… to the SAM-e Complete™ comparator product. The relative bioavailability of MSI-195 was approximately 2.8-fold higher than SAM-e … and the usual clinical laboratory tests (general …
202014 citationsDr. Moyad's Guide to Male Sexual Health: What Works and What's Worthless
MA Moyad - 2012 - books.google.com
… that go to the penis, I wonder if more men would have quit sooner… theanine in doses of 100 to 200 mg can help reduce anxiety and … SAM-e is an interesting supplement. Recent research …
20129 citationsNatural Choices for Attention Deficit Disorder: For Adults and Children Who Want to Achieve Mental Clarity
J Oelke - 2005 - books.google.com
… We will look at various areas of health and lifestyle that do affect our moods, our behavior, our energy levels, and our thinking ability. And we will look at Attention Deficit behavior in …
20051 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-03-24. DSLD Label ID: 215609. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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