Net Contents
60 Vegetarian Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
Not specified
Supplement Form
Capsule
Bar Code (UPC/SKU)
6 93749 13201 1
Product Version
B132 LB13206
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
1 ingredients report a %DV; 1 meet or exceed 100% DV.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Capsule(s) · 2–3 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Folate(L-5-Methyltetrahydrofolate) | 5 mg | 1250% |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule two to three times daily or as recommended by your health-care practitioner.
Warnings & Precautions
Precautions re: All Other
Tamper Evident: Use only if bottle is sealed.
Precautions re: Pregnant or Nursing or Prescription Medications
If pregnant, consult your health-care practitioner before using this product.
Storage
Storage
Store tightly sealed in a cool, dry place.
Formulation
Formula re: Contains
This product uses Gnosis S.p.A.’s L-5-Methyltetrahydrofolate (Extrafolate-S).
FDA Statements
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General: Product/Version Code
B132 LB13206
Brand IP Statement(s) re: (c), (TM), (SM)
Extrafolate-S is a registered trademark of Gnosis S.p.A.
Manufacturer & Distributor
Manufacturer
Thorne Research, Inc.
P.O. Box 25, Dover, Idaho, 83825, USA
1-800-228-1966
Market Reference
Thorne Research 5-MTHF 5mg 60 Capsules
Thorne4.8(506)$68.00Thorne 5-MTHF 1 mg 60 Capsules
The Healthy Place Holistic Clinic4.8(2200)$24.00Thorne Research 5-HTP
Thorne4.6(690)$39.00Thorne Research Methyl-Guard Plus 90 Capsules
Target4.8(1300)$62.005-MTHF 5mg
Atlanta Functional Medicine4.8(506)$68.005-MTHF 5mg (Thorne)
boulevardcompounding.com4.8(506)$68.00Thorne Research Melaton-5 60 Capsules
Thorne4.7(827)$22.00LowestThorne Methyl-Guard Capsules
Thorne4.8(1000)$56.00
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Village Green Apothecary
4.8 (489)Vitamin & supplements store
5415 W Cedar Ln, Bethesda, MD 20814
Kirkman
4.0 (10)Vitamin & supplements store
6400 SW Rosewood St, Lake Oswego, OR 97035
The Medicine Store
4.9 (53)Pharmacy
15415 Pinehurst Dr, Basehor, KS 66007
Moore's Compounding Pharmacy
4.3 (51)Pharmacy
5945 McArdle Rd Ste. 101, Corpus Christi, TX 78412
Research & Studies
Effect of L-Methylfolate Supplementation on Sleep for Patients with Reduced Methylenetetrahydrofolate Reductase Activity
AS Carmon, RJ Amato, SM Patel… - … of Dietary Supplements, 2024 - Taylor & Francis
… goal of this study was to evaluate the effects of L-5-MTHF … of consistency, 5 mg of 5-L-MTHF manufactured by Thorne was … any role in the study protocol or in the medical management of …
20243 citationsFolic acid, folinic acid, 5 methyl tetrahydrofolate supplementation for mutations that affect epigenesis through the folate and one-carbon cycles
Y Menezo, K Elder, A Clement, P Clement - Biomolecules, 2022 - mdpi.com
… on health, as will be further described here [3]. We will outline a rationale for replacing folic acid supplementation (especially at high doses) with 5-MTHF. … with FA at 5 mG/Day. 5MTHF …
2022248 citationsMethyltetrahydrofolate vs folic acid supplementation in idiopathic recurrent miscarriage with respect to methylenetetrahydrofolate reductase C677T and A1298C …
A Hekmatdoost, F Vahid, Z Yari, M Sadeghi… - PloS one, 2015 - journals.plos.org
… The supplements were purchased from Thorne Research Company… Our results are consistent with previous studies on healthy … study does not support any beneficial effect of 5-MTHF vs. …
201558 citationsMale Fertility Supplements: What the Research Actually Shows
J Paigen - mandrake.health
… I would always recommend 5-MTHF over folic acid. MTHFR … 5-MTHF is the form your body can use directly, making it the … clients include Thorne, Metagenics, Designs for Health, and …
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
AL Miller - Alternative medicine review, 2008 - search.ebscohost.com
… supplementation with folie acid at raising plasma 5-MTHF levels. After supplementation of 24 individuals with 5 mg foHc acid or 5 … British Women's Heart and Health Study and a meta-…
2008420 citations5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin …
C Antoniades, C Shirodaria, N Warrick, S Cai… - Circulation, 2006 - ahajournals.org
… We hypothesized that 5-MTHF would improve endothelial function … In the present study, we explored the effects of 5-MTHF on … We hypothesized that 5-MTHF acts as an effective …
2006506 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2016-08-24. DSLD Label ID: 63785. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
Related Products

100% Natural E-1000 IU
Vitamin World

100% Natural E-200 IU
Vitamin World

100% Natural E-400 IU
Vitamin World

100% Natural Vitamin D3
Whole Body Research