Net Contents
60 Vegetarian Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
Not specified
Supplement Form
Capsule
Bar Code (UPC/SKU)
6 93749 13201 1
Product Version
B132 LB13201
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
1 ingredients report a %DV; 1 meet or exceed 100% DV.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Capsule(s) · 2–3 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Folate(L-5-Methyltetrahydrofolate) | 5 mg | 1250% |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule two to three times daily or as recommended by your health care practitioner.
Warnings & Precautions
Precautions re: All Other
Tamper Evident: Use only if bottle is sealed.
Precautions re: Pregnant or Nursing or Prescription Medications
If pregnant, consult your health-care practitioner before using this product.
Storage
Storage
Store tightly sealed in a cool, dry place.
Formulation
Formula re: Type
HYPOALLERGENIC
FDA Statements
FDA Statement of Identity
DIETARY SUPPLEMENT
Other Label Statements
Seals/Symbols
(pulled apart capsule)(R)
General: Product/Version Code
B132 LB13201
Brand IP Statement(s) re: (c), (TM), (SM)
This product uses Gnosis S.p.A.’s L-5-Methyltetrahydrofolate (Extrafolate-S(R)). Extrafolate-S is a registered trademark of Gnosis S.p.A.
Manufacturer & Distributor
Manufacturer
Thorne Research, Inc.
P.O. Box 25, Dover, Idaho, 83825, USA
1-800-228-1966
Market Reference
Thorne 5-MTHF 1 mg 60 Capsules
Thorne4.8(497)$68.00Thorne Research 5-MTHF 5 mg
Pure Prescriptions4.8(497)$68.00Thorne Methyl-Guard Plus Active Folate Supplement
Target4.9(1300)$62.00Thorne Research 5-Hydroxytryptophan 90 Capsules
Thorne4.7(673)$39.00Thorne Research Melaton-5 60 Capsules
Thorne4.7(814)$22.00Thorne Methyl-Guard Capsules
Thorne4.8(999)$56.00Thorne Brain Factors 30 Caps
Target4.6(205)$51.00Methylation Stack by Thorne
Thorne4.9(33)$94.00
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Village Green Apothecary
4.8 (477)Vitamin & supplements store
5415 W Cedar Ln, Bethesda, MD 20814
Research & Studies
Effect of L-Methylfolate Supplementation on Sleep for Patients with Reduced Methylenetetrahydrofolate Reductase Activity
AS Carmon, RJ Amato, SM Patel… - … of Dietary Supplements, 2024 - Taylor & Francis
… goal of this study was to evaluate the effects of L-5-MTHF … of consistency, 5 mg of 5-L-MTHF manufactured by Thorne was … any role in the study protocol or in the medical management of …
20243 citationsFolic acid, folinic acid, 5 methyl tetrahydrofolate supplementation for mutations that affect epigenesis through the folate and one-carbon cycles
Y Menezo, K Elder, A Clement, P Clement - Biomolecules, 2022 - mdpi.com
… on health, as will be further described here [3]. We will outline a rationale for replacing folic acid supplementation (especially at high doses) with 5-MTHF. … with FA at 5 mG/Day. 5MTHF …
2022245 citationsMethyltetrahydrofolate vs folic acid supplementation in idiopathic recurrent miscarriage with respect to methylenetetrahydrofolate reductase C677T and A1298C …
A Hekmatdoost, F Vahid, Z Yari, M Sadeghi… - PloS one, 2015 - journals.plos.org
… The supplements were purchased from Thorne Research Company… Our results are consistent with previous studies on healthy … study does not support any beneficial effect of 5-MTHF vs. …
201556 citationsMale Fertility Supplements: What the Research Actually Shows
J Paigen - mandrake.health
… I would always recommend 5-MTHF over folic acid. MTHFR … 5-MTHF is the form your body can use directly, making it the … clients include Thorne, Metagenics, Designs for Health, and …
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
AL Miller - Alternative medicine review, 2008 - search.ebscohost.com
… supplementation with folie acid at raising plasma 5-MTHF levels. After supplementation of 24 individuals with 5 mg foHc acid or 5 … British Women's Heart and Health Study and a meta-…
2008416 citations5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin …
C Antoniades, C Shirodaria, N Warrick, S Cai… - Circulation, 2006 - ahajournals.org
… We hypothesized that 5-MTHF would improve endothelial function … In the present study, we explored the effects of 5-MTHF on … We hypothesized that 5-MTHF acts as an effective …
2006501 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-11-21. DSLD Label ID: 15710. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
Related Products

100% Natural E-1000 IU
Vitamin World

100% Natural E-200 IU
Vitamin World

100% Natural E-400 IU
Vitamin World

100% Natural Vitamin D3
Whole Body Research