IGF-1 Protocol

Suggested Use

Directions: Shake well before use. At bedtime spray 3-6 times under tongue; hold then swallow. May repeat in the morning if desired for added momentarily; and benefit.

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Showing representative supplement & health retailers — search above for stores in your area.

• GNC

  3.8 (33)

  Vitamin & supplements store

  13600 Baltimore Ave Spc #102, Laurel, MD 20707

  Directions(301) 604-0040

• The Vitamin Shoppe

  4.4 (104)

  Vitamin & supplements store

  2460 Market St NE #701, Washington, DC 20018

  Directions(202) 269-0809

• GNC

  4.6 (164)

  Vitamin & supplements store

  3500 East-West Hwy, Hyattsville, MD 20782

  Directions(301) 853-2566

• The Vitamin Shoppe

  4.6 (154)

  Vitamin & supplements store

  1803 Rockville Pike, Rockville, MD 20852

  Directions(301) 231-7900

• GNC

  3.8 (25)

  Vitamin & supplements store

  3467 Fort Meade Rd, Laurel, MD 20724

  Directions(301) 254-1425

• The Vitamin Shoppe

  4.4 (158)

  Vitamin & supplements store

  9101 Alaking Ct Suite 100, Capitol Heights, MD 20743

  Directions(301) 336-1450

• GNC

  4.0 (43)

  Vitamin & supplements store

  1625 K St NW, Washington, DC 20006

  Directions(202) 822-6900

• GNC

  3.9 (32)

  Vitamin & supplements store

  1728 L St NW, Washington, DC 20036

  Directions(202) 457-0097

• Serum IGF-1 concentrations change with soy and seaweed supplements in healthy postmenopausal American women

  J Teas, MR Irhimeh, S Druker, TG Hurley… - Nutrition and …, 2011 - Taylor & Francis

  … of seaweed include bioactive compounds not found in land … This study was conducted according to the guidelines described … The interaction term tested for synergy; that is, whether the …

  201142 citations

• Oral Administration of Microencapsulated B. Longum BAA-999 and Lycopene Modulates IGF-1/IGF-1R/IGFBP3 Protein Expressions in a Colorectal Murine …

  N Valadez-Bustos, EM Escamilla-Silva… - International Journal of …, 2019 - mdpi.com

  … IGFBP3 is lower in patients than in healthy individuals [2,3]. … synergistic effect of the combined probiotic BF + LYC supplementation on the expression of several IGF system components …

  201924 citations

• Efficacy of nutritional interventions as stand-alone or synergistic treatments with exercise for the management of sarcopenia

  S Damanti, D Azzolino, C Roncaglione, B Arosio… - Nutrients, 2019 - mdpi.com

  … training increases IGF-1 at muscular level [127]. In turn, … BW or providing supplements, it is recommended to supplement … according to the WHO guidelines is another efficacious modality …

  2019109 citations

• The Effects of a Novel Astragalus-Based Extract (Keyfobell Powder (KFB)) on Longitudinal Bone Growth via IGF-1 Upregulation: A Potential Growth Hormone …

  MJ Lee, D Jeong, JH Lee, J Kang, J Choi, J Seo… - Nutrients, 2025 - mdpi.com

  … herbal medicines in contemporary health applications, emphasizing … pathways, enhancement of nutritional absorption, and … predict the synergistic mechanism of multiple compounds in …

  20251 citations

• Synergistic Effects of Protein Intake and Exercise on Biomarkers of Sarcopenia: A Systematic Review

  S Cruz-Pierard, S Iñiguez-Jiménez - Biomolecules, 2026 - mdpi.com

  … as IGF-1 plays a crucial anabolic role in its maintenance [11]. … programs incorporate specific components like a frequency … action of mechanical and nutritional stimuli on anabolic …

  20261 citations

• Multi-omics-guided discovery: yeast protein alleviates glucocorticoid-induced muscle atrophy through dual activation of IGF-1/PI3K/Akt/FOXO and CaMKK/AMPK …

  Y Liang, Q Liu, X Zhang, B Li, T Hou - Food & Function, 2026 - pubs.rsc.org

  … Mechanistically, H-YP synergistically activated both the IGF-1… treatments, thus exercise and nutritional support are the main … Prkag3 expression in healthy mouse skeletal muscle, which …

  20261 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-08-26. DSLD Label ID: 36621. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.