SAMe 400 mg®
Non-Nutrient / Non-BotanicalBrand: Source Naturals
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
30
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 21078 01400 3
Product Version
SN1400 REV B132
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegetarian, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Egg
- Wheat
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Tablet(s) · 1–3 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAMe | 400 mg | — |
| SAMe Disulfate Tosylate | 800 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Use: 1 tablet 1 to 3 times daily. Take tablets on an empty stomach.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: If you are pregnant, may become pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product.
Precautions re: All Other
Use this product under medical supervision if you have bipolar disorder. In small percentage of people this product may cause nausea or gastrointestinal upset. If you experience discomfort, discontinue use. Do not use if either tamper-evident seal is broken or missing.
Precautions re: Children
Keep out of the reach of children.
Formulation
Formulation re: Other
Double Strength
Formula re: Contains
S-adenosyl-L-methionine
Formulation re: Other
Supports joint comfort, function and mobility
Formula re: Contains
Source Naturals SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients. Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage. The studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier, where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules. Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication. SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. However, levels of SAMe tend to decline with age.
Formulation re: Vegetarian/Vegan
Suitable for vegetarians.
Formulation re: Does NOT Contain
Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, preservatives, or artificial flavor or fragrance.
Formula re: Contains
S-adenosyl-L-methionine
FDA Statements
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
Copyright Source Naturals, Inc.
Manufacturer & Distributor
Distributor
Source Naturals, Inc.
P. O. Box 2118, Santa Cruz, CA, 95062
Market Reference
Source Naturals SAMe 400 mg 30 Tablets
iHerb4.7(95)$52.98Source Naturals SAMe 400mg 60 Tablets | Mood, Joint & Liver Support
Akron Nutrition Center$58.95Nature Made SAM-e Complete 400 mg
Walmart - Mayrip LLC4.5(310)$53.98Source Naturals S.O.D. 2000 Units 90 Tablets
Swanson Health Products4.1(15)$10.91LowestSource Naturals Non-GMO Tablets
Herbs Direct4.9(16)$30.08Source Naturals Wellness Formula
Whole Foods Market3.9(2500)$28.49Spring Valley SAMe Enteric Coated Caplets
Walmart4.6(188)$24.96SAMe 400 mg - 60 tabs
Nutriessential.com$64.79
Where to Buy Locally
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SameDaySupplements.com
4.5 (503)Vitamin & supplements store
64 Nancy St Unit c, West Babylon, NY 11704
The Vitamin Shoppe
4.5 (210)Vitamin & supplements store
137 E Rte 4, Paramus, NJ 07652
Nature's Trove
Vitamin & supplements store
2360 Lakewood Rd, Toms River, NJ 08755
Supplement Superstore
5.0 (1306)Vitamin & supplements store
7449 S Lindbergh Blvd, St. Louis, MO 63125
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5.0 (1203)Vitamin & supplements store
7344 W 135th St, Overland Park, KS 66223
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5.0 (351)Vitamin & supplements store
7424-A S University Blvd, Centennial, CO 80122
Supplement Superstore
5.0 (895)Vitamin & supplements store
699 Gravois Bluffs Blvd, Fenton, MO 63026
Supplement Superstore
5.0 (1389)Vitamin & supplements store
8420 Eager Rd, St. Louis, MO 63144
Research & Studies
Herbs and natural supplements, volume 2: An evidence-based guide
L Braun, M Cohen - 2014 - books.google.com
… supplements, and informed advice from their healthcare practitioner is important and expected. I hope that this book will help expand your practice by unlocking the potential of natural …
2014572 citationsMosby's handbook of herbs & natural supplements
L Skidmore-Roth - 2009 - books.google.com
… health treatment and maintenance plan. This book contains detailed monographs of 300 herbs and natural supplements, … depth of information today’s health care professionals demand. …
2009126 citationsBotanical medicines: the desk reference for major herbal supplements
DJ McKenna, K Jones, K Hughes, VM Tyler - 2012 - books.google.com
… of plants in health care. Kerry has worked with natural product companies throughout the … a toxic effect in the first trimester but at the same dose have little or no impact on the fetus …
2012247 citationsSynthetic and Natural Nutritional Supplements: Health
N Kioukia-Fougia, N Georgiadis… - Recent patents on …, 2016 - ingentaconnect.com
… supplements, several patents of application have been identified and herewith reviewed which recommend natural vegetable extracts as food supplements … and other health conditions. …
201627 citationsPolyphenols as dietary supplements: A double-edged sword
KR Martin, CL Appel - Nutrition and Dietary Supplements, 2009 - Taylor & Francis
… regarding the health effects of polyphenol-rich foods, new dietary supplements and polyphenol-rich … A dietary supplement could provide some of the same beneficial effects of dietary …
2009431 citationsWhich sources of flavonoids: complex diets or dietary supplements?
S Egert, G Rimbach - Advances in Nutrition, 2011 - academic.oup.com
… health benefits of dietary flavonoids. Fruits and vegetables, tea, and cocoa are rich natural sources … People may also take more than 1 dietary flavonoid supplement at the same time and …
2011281 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-09-25. DSLD Label ID: 296170. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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