SAMe 400 mg®
Non-Nutrient / Non-BotanicalBrand: Source Naturals
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
30
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
Not specified
Product Version
SN1400 REV B205-A
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegetarian, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Egg
- Wheat
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Tablet(s) · 1–3 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAMe | 400 mg | — |
| SAMe Disulfate Tosylate | 800 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Use: 1 tablet 1 to 3 times daily. Take tablets on an empty stomach.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: If you are pregnant, may become pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product.
Precautions re: All Other
Use this product under medical supervision if you have bipolar disorder. In a small number of people this product may cause nausea or gastrointestinal upset. If you experience discomfort, discontinue use.
Precautions re: All Other
Do not use if either tamper-evident seal is broken or missing.
Precautions re: Children
Keep out of the reach of children.
Formulation
Formula re: Contains
S-adenosyl-L-methionine 400 mg
Formulation re: Other
Improved enteric coating Supports joint comfort, function and mobility
Formula re: Contains
Source Naturals SAMe is a stable, bio-available form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed for consistent quality and optimal bioactivity. SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. A number of clinical studies have demonstrated that SAMe supplementation supports joint comfort, function and mobility in the spine, hips and knees. Preliminary research suggests that SAMe may work by supporting the production of proteoglycans, which are important components of cartilage. Numerous clinical studies have also demonstrated that SAMe can help support a positive outlook. It is able to cross the blood-brain barrier, where it is thought to affect the synthesis of neurotransmitters, and to help maintain normal membrane fluidity. SAMe works together with the B-vitamins, in particular folic acid, making it important to obtain adequate amounts of the B-vitamin complex from diet and supplements. SAMe plays a key role in transmethylation, a vital type of chemical reaction that affects the synthesis, activation, and metabolism of various biological molecules. Compounds that require this reaction include phospholipids, which are fundamental for all cell membrane functions and for cell to cell communication.
Formulation re: Vegetarian/Vegan
Suitable for vegetarians.
Formulation re: Does NOT Contain
Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, preservatives, or artificial color, flavor or fragrance.
FDA Statements
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
Copyright SOURCE NATURALS, INC.
Manufacturer & Distributor
Distributor
Source Naturals, Inc.
P. O. Box 2118, Santa Cruz, CA, 95062
Market Reference
Source Naturals SAMe 400 mg 30 Tablets
iHerb4.7(95)$32.18
Nature Made SAM-e Complete 400 mg
Walmart4.6(190)$52.97
Source Naturals Gamma E 400 Softgels
Swanson Health Products4.7(74)$27.65
Source Naturals Wellness Formula
Supplement First4.4(621)$13.99
Spring Valley SAMe
Walmart4.6(186)$24.96
Source Naturals Vitamin E 400 IU
Chinese Herbs Direct4.8(5)$25.01
NOW Foods SAMe 400 mg 60 Tablets
Cook's Natural Foods4.7(417)$34.99
Bestvite's SAMe 400mg 60 Tablets (2-Pack)
Bestvite4.7(211)$35.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
GNC
2.3 (50)Vitamin & supplements store
975 Savannah Hwy, Charleston, SC 29407
The Vitamin Shoppe
4.6 (56)Vitamin & supplements store
1102 Bowman Rd #103, Mt Pleasant, SC 29464
The Vitamin Shoppe
4.4 (391)Vitamin & supplements store
2115 Ashley Phosphate Rd, North Charleston, SC 29406
GNC
3.7 (50)Vitamin & supplements store
2150 Northwoods Blvd Spc E - 08, North Charleston, SC 29406
GNC
5.0 (3)Vitamin & supplements store
101 Lawson Dr #1990, Joint Base Charleston, SC 29404
Mission Ready Nutrition
5.0 (70)Vitamin & supplements store
101 Old Trolley Rd, Summerville, SC 29485
Supreme Nutrition Greenville
5.0 (227)Vitamin & supplements store
1143 Woodruff Rd Ste A-2, Greenville, SC 29607
Grand Strand Wholesale Supplements
4.9 (120)Vitamin & supplements store
4025 N Kings Hwy Ste 7, Myrtle Beach, SC 29577
Research & Studies
Herbs and natural supplements, volume 2: An evidence-based guide
L Braun, M Cohen - 2014 - books.google.com
… supplements, and informed advice from their healthcare practitioner is important and expected. I hope that this book will help expand your practice by unlocking the potential of natural …
2014569 citationsMosby's handbook of herbs & natural supplements
L Skidmore-Roth - 2009 - books.google.com
… health treatment and maintenance plan. This book contains detailed monographs of 300 herbs and natural supplements, … depth of information today’s health care professionals demand. …
2009126 citationsBotanical medicines: the desk reference for major herbal supplements
DJ McKenna, K Jones, K Hughes, VM Tyler - 2012 - books.google.com
… of plants in health care. Kerry has worked with natural product companies throughout the … a toxic effect in the first trimester but at the same dose have little or no impact on the fetus …
2012247 citationsSynthetic and Natural Nutritional Supplements: Health
N Kioukia-Fougia, N Georgiadis… - Recent patents on …, 2016 - ingentaconnect.com
… supplements, several patents of application have been identified and herewith reviewed which recommend natural vegetable extracts as food supplements … and other health conditions. …
201627 citationsPolyphenols as dietary supplements: A double-edged sword
KR Martin, CL Appel - Nutrition and Dietary Supplements, 2009 - Taylor & Francis
… regarding the health effects of polyphenol-rich foods, new dietary supplements and polyphenol-rich … A dietary supplement could provide some of the same beneficial effects of dietary …
2009428 citationsWhich sources of flavonoids: complex diets or dietary supplements?
S Egert, G Rimbach - Advances in Nutrition, 2011 - academic.oup.com
… health benefits of dietary flavonoids. Fruits and vegetables, tea, and cocoa are rich natural sources … People may also take more than 1 dietary flavonoid supplement at the same time and …
2011278 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-10-24. DSLD Label ID: 275626. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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