Homocysteine Defense®

Other Combinations

Brand: Source Naturals

Tablet or PillOther CombinationsOn Market
Click to view full label

Net Contents

120 Tablet(s)

Serving Size

2 Tablet(s)

Servings Per Container

60

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

0 21078 01039 5

Product Version

SN1039 REV C211 FG-110912

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

7Active Ingredients

7 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

5% Daily Value Coverage

5 ingredients report a %DV; 3 meet or exceed 100% DV.

2Dietary Attributes

Label states: Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Egg
  • Wheat
  • Soy
  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Tablet(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Calories5 Calorie(s)—
Protein1 Gram(s)2%
Vitamin B6(Pyridoxine Hydrochloride)50 mg2941%
Folate1360 mcg DFE340%
Folic Acid800 mcg—
Vitamin B12(Cyanocobalamin)500 mcg20833%
Calcium(Dibasic Calcium Phosphate)90 mg7%
Trimethylglycine1 Gram(s)—

Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients

Dibasic Calcium PhosphateStearic Acidmodified Cellulose GumSilicaMagnesium Stearate

Target Groups

VegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Use: 2 tablets daily.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Precautions re: All Other

Do not use if either tamper-evident seal is broken or missing.

Precautions re: Children

Keep out of the reach of children.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Other

Helps support the cardiovascular system

Formulation re: Other

Source Naturals Homocysteine Defense is an excellent formula which may provide support to the cardiovascular system.

Formula re: Contains

Source Naturals Homocysteine Defense is an excellent formula which may provide support to the cardiovascular system. Trimethylglycine (TMG), vitamins B-6, B-12, and folic acid may help in the conversion of homocysteine to other substances, including methionine, thus preventing an unwanted build-up of homocysteine.*

Formulation re: Vegetarian/Vegan

Suitable for vegetarians.

Formulation re: Does NOT Contain

Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no starch, preservatives, or artificial color, flavor or fragrance.

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

Brand IP Statement(s) re: (c), (TM), (SM)

Copyright SOURCE NATURALS, INC.

Manufacturer & Distributor

Distributor

Source Naturals, Inc.

P. O. Box 2118, Santa Cruz, CA, 95062

Market Reference

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Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • ONE STOP NUTRITION

    4.0 (60)

    Vitamin & supplements store

    24786 N 67th Ave #8, Glendale, AZ 85310

  • Discount Nutrition Superstore

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    288 E Greenway Pkwy Ste 104, Phoenix, AZ 85022

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    7708 W Bell Rd Ste 150, Glendale, AZ 85308

  • Power Nutrition - Vitamins & Sports Supplements

    4.6 (33)

    Vitamin & supplements store

    5052 W Olive Ave, Glendale, AZ 85302

  • Nutritional Brands

    4.2 (5)

    Health food store

    1610 W Whispering Wind Dr, Phoenix, AZ 85085

  • Peak Nutrition

    5.0 (470)

    Vitamin & supplements store

    6501 E Greenway Pkwy Unit 150, Scottsdale, AZ 85254

  • MSM Nutraceuticals LLC dba MSM Health Solutions

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    2103 W Parkside Ln #107, Phoenix, AZ 85027

  • One Stop Nutrition

    4.9 (222)

    Vitamin & supplements store

    2814 W Bell Rd Ste 1460, Phoenix, AZ 85053

Research & Studies

  • Metabolomics and biochemical benefits of multivitamin and multimineral supplementation in healthy individuals: a pilot study

    MC Sánchez, A Herráiz, MJ Ciudad, M Arias, R Alonso… - Foods, 2024 - mdpi.com

    … As previously stated, our study achieved a 25%–27% reduction in homocysteine values by supplementing the supply of dietary micronutrients with the complex (Table 3 and Table 4). …

    20244 citations
  • Vitamins, Vascular Health and Disease

    G Ayoub - Nutrients, 2025 - mdpi.com

    … Folate is noted for its central function in one-carbon metabolism and in converting homocysteine to methionine, thereby reducing vascular toxicity. We cover natural dietary sources of …

    202510 citations
  • Homocysteine, nutrition, and gut microbiota: a comprehensive review of current evidence and insights

    D Agostini, A Bartolacci, R Rotondo, MF De Pandis… - Nutrients, 2025 - mdpi.com

    … An elevated concentration of homocysteine in the plasma, … An interaction between metabolic pathways of homocysteine … exert an influence on homocysteine levels and related disease …

    202518 citations
  • Therapeutic effect of targeted antioxidant natural products

    S Mukherjee, H Chopra, R Goyal, S Jin, Z Dong, T Das… - Discover Nano, 2024 - Springer

    … Not only may these chemicals increase endogenous antioxidant defenses, affect … the primary classes of natural antioxidants found in different plant and animal source that contribute to …

    202448 citations
  • Homocysteine and hyperhomocysteinaemia

    BL Zaric, M Obradovic, V Bajic… - Current medicinal …, 2019 - ingentaconnect.com

    … The effect of homocysteine (Hcy) on human health was discovered in the mid-twentieth century when McCully and colleagues [1] dedicated their research to the disorder that leads to …

    2019368 citations
  • Health effects of mixed fruit and vegetable concentrates: a systematic review of the clinical interventions

    A Esfahani, JMW Wong, J Truan, CR Villa… - Journal of the …, 2011 - Taylor & Francis

    … vitamins found in plant foods (β-carotene, vitamins C and E) and folate. Functional changes, such as reduced serum homocysteine … ; in addition, the health advantages on markers of …

    2011152 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-08-23. DSLD Label ID: 273056. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.