Brand: Signature Supplements

CapsuleNon-Nutrient/Non-BotanicalOn Market

Functions

Click to view full label

Net Contents

100 Capsule(s)

Serving Size

1–2 Capsule(s)

Servings Per Container

50

Supplement Form

Capsule

Bar Code (UPC/SKU)

Not specified

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1–2 Capsule(s) · 1 per day

IngredientAmount Per Serving
Methylsulfonylmethane868 mg

Not Present

Other Ingredients

CelluloseDiatomaceous Earth

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) to two (2) capsules daily, preferably with a meal.

Warnings & Precautions

Precautions re: Children

Keep out of reach of children.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not take this product within 2 hours of taking medications or follow the advice of your health care providers. Warning: Pregnant or lactating women should consult a doctor before using any product. Consult doctor before use if you have, or have had, kidney disease, if you are on a magnesium-restricted diet or if you are taking any medications or remedies such as those to treat high blood pressure, heart medications, muscle relaxants or diuretics.

Precautions re: All Other

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or low blood pressure.

Precautions re: Children

Not intended for use by persons under the age of 18

Storage

Storage

Store in a dry place and avoid excessive heat.

Formulation

Formulation re: Does NOT Contain

No: Chemical Fillers or Binders, Artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Formulation re: Other

From a GMP Facility

Formulation re: Other

Important for joint cartilage

FDA Statements

FDA Statement of Identity

Dietary Supplement

Manufacturer & Distributor

Distributor

Signature Supplements

P.O. Box 1112, San Clemente, CA

Market Reference

$23.97 – $93.00· 7 listings
  • MSM Joint Support Powder

    McGregor General Store4.7(614)
    $39.99
  • Glucosamine MSM

    kauairx.com4.9(9)
    $93.00
  • MSM Powder 230 gms

    Curated Wellness4.5(52)
    $40.00
  • MSM Joint Formula by Natural Factors | Joint Comfort & Mobility | Coal Harbour Pharmacy Vancouver 180 Capsules

    Coal Harbour Pharmacy4.7(6)
    $59.00
  • Glucosamine/MSM

    Curated Wellness5.0(1)
    $53.20
  • MSM Joint Formula works to maintain the structural integrity of joints 180 Capsules

    Win in Health4.8(28)
    $23.97Lowest
  • MSM Joint Formula Natural Factors

    Coal Harbour Pharmacy4.8(28)
    $63.00

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • MJ NUTRITION

    5.0 (2)

    Vitamin & supplements store

    2030 W Washington Blvd, Los Angeles, CA 90018

  • The Vitamin Shoppe

    4.4 (246)

    Vitamin & supplements store

    101 N Fairfax Ave, Los Angeles, CA 90036

  • Green Farm Nutrition

    4.3 (12)

    Vitamin & supplements store

    4972 W Pico Blvd Reference, Los Angeles, CA 90019

  • N101

    5.0 (419)

    Vitamin & supplements store

    6252 Romaine St, Los Angeles, CA 90038

  • GNC

    4.1 (30)

    Vitamin & supplements store

    4550 W Pico Blvd Ste C304, Los Angeles, CA 90019

  • Vit-Al Supplements

    Vitamin & supplements store

    2607 Brighton Ave, Los Angeles, CA 90018

  • 한미건강센터

    5.0 (4)

    Vitamin & supplements store

    3158 W Olympic Blvd, Los Angeles, CA 90006

  • Nutritional Warehouse

    4.8 (34)

    Vitamin & supplements store

    2118 Lincoln Blvd, Venice, CA 90291

Research & Studies

  • Early-Life Hydrogen Sulfide Signaling as a Target for Cardiovascular–Kidney–Metabolic Syndrome Reprogramming

    CN Hsu, YJ Lin, CY Hou, YW Chen, YL Tain - Antioxidants, 2025 - pmc.ncbi.nlm.nih.gov

    Hydrogen sulfide (H2S), once regarded solely as a toxic gas, is now recognized as a vital endogenous signaling molecule with important roles in both health and disease. Growing …

    20254 citations
  • Preclinical Impact of Blueberry Supplementation in Healthy and Prediabetic Conditions-Focus on Gut Microbiota and Hepatic Mitochondria Bioenergetics

    SRRP Nunes - 2021 - search.proquest.com

    Prediabetes, recognized as a state of high risk for the development of type 2 diabetes mellitus (T2DM) and related complications, is certainly a privileged phase to implement strategies …

    20211 citations
  • NAD+ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

    YJ Wang, DS Gaul, E Gorica, J Pahla, Z Wang… - Atherosclerosis, 2025 - Elsevier

    Background and Aims NAD + (nicotinamide adenine dinucleotide) is a cosubstrate of the sirtuins (SIRT) that are activated upon caloric restriction. Supplementing NAD + precursors …

    20258 citations
  • Environmental triggers of dermatomyositis: a narrative review

    CE Bax, S Maddukuri, A Ravishankar… - Annals of …, 2021 - pmc.ncbi.nlm.nih.gov

    … ’re My Everything, a supplement containing Spirulina platensis, Aphanizomenon … methylsulfonylmethane. After discontinuing the supplement and completing a 10-day course of 40 …

    202165 citations
  • HIV and the gut microbiota: composition, consequences, and avenues for amelioration

    I Vujkovic-Cvijin, M Somsouk - Current HIV/AIDS Reports, 2019 - Springer

    … with men (MSM) and that Bacteroides are depleted in MSM. As MSM are most commonly … gut microbiota surveys that are not balanced in numbers of MSM in their HIV-infected and HIV-…

    2019194 citations
  • Adult-onset nicotinamide supplementation prevents the emergence of early-life stress driven inflammatory signatures, blood-brain barrier compromise, hippocampal …

    P Chaudhari, N Pange, A Singla, S Suryavanshi… - 2026 - researchsquare.com

    … We treated control and MS cohorts with vehicle or NAM (100 mg/kg/day) 248 supplementation in drinking water commencing at eight months of age for a duration of five 249 months [Fig…

    20261 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-09-25. DSLD Label ID: 338850. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.