Circulation Improvenone

Botanicals with Nutrients

Brand: Signature Supplements

CapsuleBotanical with NutrientsOn Market
Click to view full label

Net Contents

100 Capsule(s)

Serving Size

2 Capsule(s)

Servings Per Container

50

Supplement Form

Capsule

Bar Code (UPC/SKU)

Not specified

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

6Active Ingredients

6 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 2 Capsule(s) · 1 per day

IngredientAmount Per Serving
Butcher's Broom(Ruscus aculeatus)250 mg
Horse Chestnut150 mg
Hawthorn(Crataegus oxyacantha)150 mg
Ginger150 mg
L-Arginine50 mg
Cayenne(Capsicum annuum)50 mg

Not Present

Other Ingredients

CelluloseDiatomaceous Earth

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, more if needed.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

As a reminder, discuss the supplements and medications you take with your health care providers. Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Formulation

Formulation re: Does NOT Contain

No: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Formulation re: Other

From a GMP facility

Formula re: Contains

Circulation Improve with Butchers Broom & Hawthorn

Formulation re: Other

Support the body's efforts to carry vital life giving properties to all parts of the body. Lack of circulation can lead to more complicated health problems such as a stroke, chest pains, kidney damage and heart attack. Even stress or injury can cause poor circulation.

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

General Statements: All Other Content

Every day your heart pumps around 1800 gallons of blood through your system.

Manufacturer & Distributor

Distributor

Signature Supplements

P.O. Box 1112, San Clemente, CA

Market Reference

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Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Research & Studies

  • The role of food supplementation in microcirculation—A comprehensive review

    D Raheem, A Raposo, A Saraiva, F Ramos… - …, 2021 - research.ulapland.fi

    … review of the impact of food supplementation on microcirculation by analyzing the European and American legal food supplements framework and the importance of food safety/food …

    202140 citations
  • … of Microbiota‐Derived Bile Acids Linked to Symptom Amelioration in Crohn's Disease: Insights From a Randomized Clinical Trial With Xanthohumol Supplementation

    PE Jamieson, I Gu, NJ Reichart… - Molecular nutrition & …, 2026 - Wiley Online Library

    … microbial products into systemic circulation, exposing the immune … Disruptedenterohepatic circulation of bile acids impairs … Lastly, we aimed to measure the signature of XN metabolism …

    2026
  • Enriched marine oil supplements increase peripheral blood specialized pro-resolving mediators concentrations and reprogram host immune responses: a randomized …

    PR Souza, RM Marques, EA Gomez, RA Colas… - Circulation …, 2020 - ahajournals.org

    … Given that essential fatty acids are precursors in the biosynthesises of SPM, the aim of the present study was to establish the relationship between supplementation and peripheral SPM …

    2020179 citations
  • Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support

    KC Yang, KA Yamada, AY Patel, VK Topkara… - Circulation, 2014 - ahajournals.org

    … -only Data Supplement) resulted in improved … Data Supplement) demonstrated that 97.3% (36 of 37) of these cardiac samples can be correctly classified by lncRNA expression signature…

    2014525 citations
  • Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

    I Tzoulaki, R Castagne, CL Boulange… - European heart …, 2019 - academic.oup.com

    … of biological signatures underlying complex traits as well as potential for new prognostic and diagnostic markers. In this study, we examined the serum metabolic signature of measures …

    2019204 citations
  • Circulating amino acid signature features urea cycle alterations associated with coronary artery disease

    L Prechtl, J Carrard, H Gallart-Ayala, R Borreggine… - Scientific reports, 2024 - nature.com

    Coronary artery disease (CAD) remains a leading cause of death worldwide and imposes a substantial socioeconomic burden on healthcare. Improving risk stratification in clinical …

    202413 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-09-25. DSLD Label ID: 338657. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.