Choline 250 mgnone

Vitamins

Brand: Signature Supplements

CapsuleVitaminOn Market
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Net Contents

100 Capsule(s)

Serving Size

1–2 Capsule(s)

Servings Per Container

50

Supplement Form

Capsule

Bar Code (UPC/SKU)

Not specified

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1–2 Capsule(s) · 1 per day

IngredientAmount Per Serving
Choline(Choline)500 mg

Not Present

Other Ingredients

CelluloseDiatomaceous Earth

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) to two (2) capsules daily, preferably with a meal.

Warnings & Precautions

Precautions re: Children

Keep out of reach of children.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not take this product within 2 hours of taking medications or follow the advice of your health care providers. Warning: Pregnant or lactating women should consult a doctor before using any product. Consult doctor before use if you have, or have had, kidney disease, if you are on a magnesium-restricted diet or if you are taking any medications or remedies such as those to treat high blood pressure, heart medications, muscle relaxants or diuretics.

Precautions re: All Other

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or low blood pressure.

Precautions re: Children

Not intended for use by persons under the age of 18

Storage

Storage

Store in a dry place and avoid excessive heat.

Formulation

Formulation re: Does NOT Contain

No: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, sugar, gluten, starch or wheat.

Formulation re: Other

From a GMP facility

FDA Statements

FDA Statement of Identity

Dietary Supplement

Manufacturer & Distributor

Distributor

Signature Supplements

P.O. Box 1112, San Clemente, CA

Market Reference

$11.09 – $114.15· 11 listings
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  • Healthy Origins Cognizin Citicoline

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Where to Buy Locally

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Research & Studies

  • Choline supplements: An update

    U Kansakar, V Trimarco, P Mone, F Varzideh… - Frontiers in …, 2023 - frontiersin.org

    … Similarly, maximum velocity and maximum mechanical power were improved by the administration of 250 mg GPC (56) and nutritional supplements containing 300 mg or 150 mg GPC …

    2023134 citations
  • Choline in immunity: a key regulator of immune cell activation and function

    C Maia, CW Fung, E Sanchez-Lopez - Frontiers in Immunology, 2025 - frontiersin.org

    … and betaine synthesis, choline serves as a methyl donor for … how immune cells utilize and metabolize choline, as well as its … of choline supplementation and the potential use of choline-…

    202514 citations
  • Comparison between egg intake versus choline supplementation on gut microbiota and plasma carotenoids in subjects with metabolic syndrome

    MS Thomas, M DiBella, CN Blesso, O Malysheva… - Nutrients, 2022 - mdpi.com

    … Thus, this study highlights that similar to healthy young subjects consuming ∼400 mg/d choline either via eggs or choline supplementation, [18], plasma TMAO concentration is not …

    202226 citations
  • Prenatal Choline and Betaine Differentially Program Adult Hepatic One-Carbon Metabolism in Wistar Rats

    GV Shelp, J Tang, J Dong, M Al-Issa… - Journal of Agricultural …, 2026 - ACS Publications

    Choline, an essential methyl donor nutrient, and its oxidation … Gestational choline or betaine supplementation lowered Wistar … Choline and betaine raised hepatic S-adenosylmethionine (…

    2026
  • Differential metabolism of choline supplements in adult volunteers

    KA Böckmann, AR Franz, M Minarski… - European journal of …, 2022 - Springer

    … We compared four different choline supplements for their impact on plasma concentration and kinetics of choline, betaine as a methyl donor and trimethylamine oxide (TMAO) as a …

    202243 citations
  • Modulation of liver cholesterol homeostasis by choline supplementation during fibrosis resolution

    E Saijou, Y Kamiya, K Fujiki, K Shirahige, R Nakato - Heliyon, 2024 - cell.com

    … choline supplementation as a potential therapeutic approach. This study aimed to explore the therapeutic potential of choline supplementation … that choline supplementation significantly …

    20247 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-09-25. DSLD Label ID: 338654. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.