DIM + I3C®

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Serving Size: 1 Capsule(s) · 1–2 per day

Not Present

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• The B-12 Store at Florida Mall

  4.8 (24)

  Vitamin & supplements store

  8001 S Orange Blossom Trl Ste. 548, Orlando, FL 32809

  Directions(321) 800-6298

• Natural Vitamins

  4.4 (42)

  Manufacturer

  4400 NW 133rd St, Opa-locka, FL 33054

  Directions(305) 265-1660

• Your Wellbeing

  5.0 (1)

  Vitamin & supplements store

  Linbro Business Park, 13 Gemini St, Frankenwald, Sandton, 2090, South Africa

  Directions+27 10 003 3521

• Amrita Nutrition UK

  4.6 (99)

  Wholesaler

  The Old Chapel, 8 Mortimer St, Sheffield City Centre, Sheffield S1 4SF, United Kingdom

  Directions+44 114 700 5676

• Nature's Dynamics

  4.9 (103)

  Vitamin & supplements store

  3802 Silver Star Rd, Orlando, FL 32808

  Directions(813) 909-9191

• Unveiling the multifaceted pharmacological actions of indole-3-carbinol and diindolylmethane: a comprehensive review

  Y Srikanth, DH Reddy, VL Anusha, N Dumala… - Plants, 2025 - mdpi.com

  … on I3C and DIM. Overall, this study marks a sublime effort to provide an in-depth review of I3C and DIM … the non-anticancer properties of I3C and DIM using databases such as Pubmed, …

  202517 citations

• Cellular, molecular and biological insight into chemopreventive and therapeutic potential of 3, 3'-diindolylmethane (DIM)

  S Banerjee, MA Parasramka, FH Sarkar - Nutraceuticals and Cancer, 2011 - Springer

  … DIM is dimeric bioactive product of Indole 3-carbinol generated in acid environment of the stomach following consumption of diet rich in cruciferous vegetables. Other relevant …

  201111 citations

• 3, 3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways

  OD Reyes-Hernández, G Figueroa-González… - Cancer cell …, 2023 - Springer

  … of DIM/I3C, we considered controlled experiments that assess the anti-tumor activities of I3C and DIM compounds. The main findings on the biological activity of I3C and DIM were …

  202396 citations

• Glucosinolates in human health: Metabolic pathways, bioavailability, and potential in chronic disease prevention.

  S Baldelli, M Lombardo, A D'Amato, S Karav… - Foods, 2025 - search.ebscohost.com

  … as indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM), which contribute to a range of health … These approaches seek to increase GSL content in edible plants, thereby maximizing …

  202547 citations

• Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

  C Hammerschmidt-Kamper, D Biljes, K Merches… - PLoS …, 2017 - journals.plos.org

  … In conclusion, we showed that dietary I3C or its metabolites such as DIM activate AhR in the gut and contribute to the generation of anti-inflammatory milieu in the gut. This supports vital …

  201746 citations

• The impact of 3, 3'-diindolylmethane on estradiol and estrogen metabolism in postmenopausal women using a transdermal estradiol patch

  MS Newman, J Smeaton - Menopause, 2024 - journals.lww.com

  … converted to DIM which is its major active product in vivo.As the vast majority of the effects of I3C come from DIM, we will use DIM in this study to refer to supplements labeled I3C or DIM. …

  20244 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-01-22. DSLD Label ID: 259041. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.