REMfresh Extra Strength®
Non-Nutrient / Non-BotanicalBrand: REMfresh
Functions
Net Contents
12 Caplet(s)
Serving Size
1 Caplet(s)
Servings Per Container
12
Supplement Form
Other (e.g. tea bag)
Bar Code (UPC/SKU)
8 57150 00606 8
Product Version
P1186C05 C21 12478527 VC16-1247D
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Wheat
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Caplet(s) · 1–2 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| UltraMel(Melatonin) | 5 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Usage: Adults, take 1 caplet 30 to 90 minutes before intended bedtime. Do not exceed 2 caplets nightly.
Warnings & Precautions
Precautions re: All Other
Intended for occasional sleeplessness.
Precautions re: Allergies
Contains: Wheat
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Consult a healthcare provider if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.
Precautions re: Children
Warning: Consult a healthcare provider if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.
Precautions re: All Other
Do not drive or operate machinery when taking melatonin.
Precautions re: Pregnant or Nursing or Prescription Medications
This product may be contraindicated for individuals taking corticosteroids.
Precautions re: Children
Keep out of reach of children.
Precautions re: All Other
Do not use if blister is torn or ripped or if there is any other evidence of tampering.
Precautions re: Allergies
Contains bioengineered food ingredient.
Storage
Storage
Store in a cool, dry place.
Formulation
Formula re: Contains
Trouble sleeping? As we age and lead busier lives, our bodies produce less melatonin, the key ingredient we need to fall asleep and stay asleep. REMfresh, made with 99% ultrapure UltraMel melatonin, helps support the body’s own natural levels of melatonin for up to 7 hours.
Formulation re: Other
The REMfresh advantage Only REMfresh has the breakthrough melatonin IPP (Ion-Powered Pump) technology that promotes continuous release and absorption, allowing you to sleep longer and wake up ready to conquer the day.
Formulation re: Other
REMfrest 7 hour absorption, known as the MESA-WAVE, has been shown in a clinical trial. Fall asleep faster Stay asleep longer Improve sleep quality Wake up Refreshed
Formula re: Contains
REMfresh Extra Strength has 5 mg of melatonin per serving compared to the 0.5 mg and 2 mg per serving REMfresh products.
Formulation re: Other
Clinically tested
Formula re: Contains
Advanced Ion-powered melatonin
Formulation re: Other
7 hour absorption
Formulation re: Other
Fall asleep faster Say asleep longer Improve sleep quality Wake up REfreshed
Formula re: Contains
5 mg UltraMel Melatonin
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
Targeted melatonin level For illustrative purposes only. Vista Color
General Statements: All Other Content
#1 Sleep Doctor recommended Among primary care physicians with a certification in sleep disorders who recommended a non-prescription sleep aid brand. IQVIA ProVoice 2020 survey.
Brand IP Statement(s) re: (c), (TM), (SM)
REMfresh is protected by U.S. patents No.: 8,691,275; 9,186,351; 9,241,926; 9,549,900; 10,226,447; 10,751,323.
General Statements: All Other Content
Questions/comments: Call us toll free 1-866-554-7071 or visit www.REMfresh.com
General Statements: All Other Content
REM Absorption Kinetics Trial (REMAKT) a pharmacokinetic trial of 5 mg REMfresh, is not a sleep study. Approved after peer review and then published in Primary Care Companion for CNS Disorders, 2019.
General Statements: All Other Content
Individual results may vary.
Brand IP Statement(s) re: (c), (TM), (SM)
All trademarks are owned by Societe des Produits S.S., Vevey, Switzerland. 2021 Nestle.
Manufacturer & Distributor
Distributor
Nestle HealthCare Nutrition, Inc.
Bridgewater, NJ, 08807, USA
1-866-554-7071
Market Reference
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Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.3 (128)Vitamin & supplements store
3691 28th St SE, Grand Rapids, MI 49512
Mel's Nutritión
5.0 (11)Vitamin & supplements store
940 Cesar E. Chavez Ave SW, Grand Rapids, MI 49503
Forever Nutrition
5.0 (28)Vitamin & supplements store
5202 Northland Dr NE, Grand Rapids, MI 49525
Nature's Remedies
5.0 (5)Vitamin & supplements store
2851 Michigan St NE, Grand Rapids, MI 49506
GNC
3.9 (34)Vitamin & supplements store
3191 28th St SE Ste B105, Kentwood, MI 49512
Harvest Health Foods
4.6 (124)Vitamin & supplements store
6807 Cascade Rd SE, Grand Rapids, MI 49546
Health Store
4.8 (20)Vitamin & supplements store
100 S Lafayette St, Greenville, MI 48838
Nutrifuel® Nutrition
5.0 (9)Vitamin & supplements store
1345 Monroe Ave NW Suite 121, Grand Rapids, MI 49505
Research & Studies
36-Month Post Marketing Surveillance Report For REMfresh®, The First And Only Drug-Free Sleep Product Of Its Type1, Shows Excellent Safety And …
L Lézard - lelezard.com
… mg (Lite), 2 mg and 5mg (Extra Strength) UltraMel ® melatonin. UltraMel melatonin is a … REMfresh is a dietary supplement and is regulated under the Federal Dietary Supplement Health …
A randomized clinical trial of the impact of melatonin on influenza vaccine: Outcomes from the melatonin and vaccine response immunity and chronobiology study …
RU Lee, NL Watson, GL Glickman, L White… - Human vaccines & …, 2024 - Taylor & Francis
… Participants randomized to the treatment group were given REMfresh® 5 mg caplets (Nestle Health Science), an OTC melatonin supplement as recommended by a board-certified …
20244 citationsExogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity
K Oda, J Danko, E Villasante… - Frontiers in …, 2025 - frontiersin.org
… were enrolled after eligibility/health screening and informed written consent. … REMfresh ® 5mg caplets (Nestle Health Science), an over the counter (OTC) melatonin supplement…
2025Melatonin Supplementation in Young Adults: Its Prevalence and Effect on Nocturnal Sleep and Morning Cognition
EMDG Wernette - 2023 - search.proquest.com
… supplements in young adults with healthy sleep. The evidence on whether melatonin affects sleep in young individuals with health … We chose to use REMfresh brand melatonin because …
2023Influenza vaccine response is predicted by chronotype and differentially associated with pre-and post-vaccination sleep
EM Harrison, RU Lee, CK Porter, SD Isidean… - … , & Immunity-Health, 2026 - Elsevier
… Participants in the melatonin group were provided with melatonin caplets (REMfresh 5 mg, Nestle Health Science) at V1 and instructed to take them one hour before bedtime for 14 …
2026Effects of absorption kinetics on the catabolism of melatonin released from CAP-coated mesoporous silica drug delivery vehicles
I Moroni, AE Garcia-Bennett - Pharmaceutics, 2021 - mdpi.com
… that vary from 1.99 mg (REMfresh ® [8]) to 20 mg (Nutricology ® ). Melatonin can be purchased both as over-the-counter products and with a medical prescription, but its efficacy for …
20216 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-03-22. DSLD Label ID: 287203. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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