REMfresh®
Non-Nutrient / Non-BotanicalBrand: REMfresh
Functions
Net Contents
12 Caplet(s)
Serving Size
1 Caplet(s)
Servings Per Container
12
Supplement Form
Other (e.g. tea bag)
Bar Code (UPC/SKU)
8 57150 00612 9
Product Version
44174715 H21 12473932 VC16-1247D REV.02.2022
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Wheat
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Caplet(s) · 1–5 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| UltraMel(Melatonin) | 2 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested usage: Take 1 caplet 30 to 90 minutes before intended bedtime. For extra suppport, take 2 caplets nightly. Do not exceed 5 caplets nightly. Intended for occasional sleeplessness.
Warnings & Precautions
Precautions re: Allergies
Contains: Wheat
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Consult a healthcare provider if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.
Precautions re: Children
Warning: Consult a healthcare provider if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.
Precautions re: All Other
Do not drive or operate machinery when taking melatonin.
Precautions re: Pregnant or Nursing or Prescription Medications
This product may be contraindicated for individuals taking corticosteroids.
Precautions re: Children
Keep out of reach of children.
Precautions re: All Other
Do not use if blister is torn or ripped or if there is any other evidence of tampering.
Precautions re: Allergies
Contains a bioengineered food ingredient.
Storage
Storage
Store in a cool, dry place.
Formulation
Formula re: Contains
Trouble sleeping? As we age and lead busier lives, our bodies produce less melatonin, the key ingredient we need to fall asleep and stay asleep. REMfresh, made with 99% ultrapure UltraMel melatonin, helps support the body's own natural levels of melatonin for up to 7 hours. The REMfresh advantage Only REMfresh has the breakthrough melatonin IPP (Ion-Powered Pump) technology that promotes continuous release and absorption, allowing you to sleep longer and wake up ready to conquer the day.
Formulation re: Other
Clinically tested
Formula re: Contains
Advanced ion-powered melatonin
Formulation re: Other
7 hour absorption Fall asleep faster Stay asleep longer Improve sleep quality Wake up REfreshed
Formula re: Contains
REMfresh 2 mg UltraMel melatonin
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
REMfresh 7 hour absorption, known as the MESA-WAVE, has been shown in a clinical trial.
General Statements: All Other Content
#1 Sleep doctor recommended Among primary care physicians with a certification in sleep disorders who recommended a non-prescription sleep aid brand. IQVIA ProVoice 2020 survey
Brand IP Statement(s) re: (c), (TM), (SM)
REMfresh is protected by U.S. patents No.: 8,691,275; 9,186,351; 9,241,926; 9,549,900; 10,226,447; 10,751,323.
General Statements: All Other Content
Questions/comments: Call us toll free 1-866-554-7071 Or visit www.REMfresh.com REM Absorption Kinetics Trial (REMAKT), a pharmacokinetic trial of 5 mg REMfresh, not a sleep study. Approved after peer review and then published in Primary Care Companion for CNS Disorders, 2019. Individual results may vary.
Brand IP Statement(s) re: (c), (TM), (SM)
All trademarks are owned by Societe des Produits Nestle S.A., Vevey, Switzerland. Copyright 2022 Nestle.
General Statements: All Other Content
Vista Color
Manufacturer & Distributor
Distributor
Nestle HealthCare Nutrition, Inc.
Bridgewater, NJ, 08807, USA
1-866-554-7071
Market Reference
RepHresh Vaginal Gel
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Walmart4.5(61)$19.18Allergan Refresh Celluvisc Eye Lubricant Gel Eye Drops
Target4.4(745)$16.29Re-Fresh Vanilla Bean Tea Smoke Odor Eliminator 4 FL OZ 118ML Non-Aerosol (2x Pieces) | Triple Traders
Triple Traders5.0(6)$14.99Refresh Tears PF Lubricant Eye Drops
Hy-Vee3.5(105)$16.99Refresh Relieva Lubricant Eye Drops
Target4.1(537)$16.79Refresh Optive Advanced Lubricant Eye Drops
Rexall4.7(377)$19.49
Where to Buy Locally
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Time 4 Nutrition
4.8 (63)Vitamin & Supplements Shop
3A London Rd, Purbrook, Waterlooville PO7 5LQ
Powerhouse Supplements Ltd
5.0 (4)Vitamin & Supplements Shop
5 Oak Tree Way, Eastleigh SO50 4JN
Holland & Barrett - Southampton Shirley
4.6 (31)Vitamin & Supplements Shop
53 Shirley High St, Shirley, Southampton SO15 3NN
VITARA Wellness uk
5.0 (2)Vitamin & Supplements Shop
181 Langdown Rd, Hythe, Southampton SO45 6EJ
Miami Supps Southampton
4.9 (359)Vitamin & Supplements Shop
403 Shirley Rd, Shirley, Southampton SO15 3JD
Miami Supps Portsmouth
4.9 (138)Vitamin & Supplements Shop
Unit 1, 122-124 London Rd, Hilsea, Portsmouth PO2 9DD
365 Nutrition
5.0 (137)Vitamin & Supplements Shop
28 Bridge Rd, Park Gate, Southampton SO31 7GF
Holland & Barrett - Winchester
3.5 (15)Vitamin & Supplements Shop
18 High St, Winchester SO23 9JX
Research & Studies
36-Month Post Marketing Surveillance Report For REMfresh®, The First And Only Drug-Free Sleep Product Of Its Type1, Shows Excellent Safety And …
L Lézard - lelezard.com
… REMfresh was designed as a hydrogel matrix tablet with its patented, scientifically … REMfresh is a dietary supplement and is regulated under the Federal Dietary Supplement Health and …
0388 CLINICAL EVALUATION OF THE ION POWERED PUMP (IPP) MELATONIN DELIVERY SYSTEM
DC Brodner, SM Shah - Sleep, 2017 - search.proquest.com
… in a regional military healthcare network, focusing on the … Melatonin supplementation has been shown to promote and … IPP-melatonin delivery system (REMfresh) was designed to …
2017Exogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity
K Oda, J Danko, E Villasante… - Frontiers in …, 2025 - frontiersin.org
… were enrolled after eligibility/health screening and informed written consent. … REMfresh ® 5mg caplets (Nestle Health Science), an over the counter (OTC) melatonin supplement…
2025Melatonin Supplementation in Young Adults: Its Prevalence and Effect on Nocturnal Sleep and Morning Cognition
EMDG Wernette - 2023 - search.proquest.com
… supplements in young adults with healthy sleep. The evidence on whether melatonin affects sleep in young individuals with health … We chose to use REMfresh brand melatonin because …
20230394 Effect of Background Noise on Sleep Quality
L Taranto-Montemurro, L Messineo, S Sands… - Sleep, 2017 - researchgate.net
… Assessment of the taped interviews/sessions suggests a high level of skill in these health … The IPP-melatonin (ion powered pump melatonin delivery system; REMfresh) was developed …
201711 citations0399 Observed Hypnotic Effects with a Continuous-Release Ion Powered Pump Melatonin Delivery System: Self-Reported Patient Outcomes Study Results …
DC Brodner, DJ Seiden, SM Shah - Sleep, 2019 - search.proquest.com
… medicines/dietary supplements, sourcing them through a range of outlets, ie health-food … received a sample of CRA-melatonin (Remfresh) from their physicians were invited to complete …
20194 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-08-24. DSLD Label ID: 289155. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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