REMfresh®
Non-Nutrient / Non-BotanicalBrand: REMfresh
Functions
Net Contents
36 Caplet(s)
Serving Size
1–5 Caplet(s)
Servings Per Container
36
Supplement Form
Other (e.g. tea bag)
Bar Code (UPC/SKU)
8 57150 00636 5
Product Version
44174396 H21 12473930 VC16-1248D REV.02.2022
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Wheat
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1–5 Caplet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| UltraMel(Melatonin) | 2 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested usage: Take 1 caplet 30 to 90 minutes before intended bedtime. For extra suppport, take 2 caplets nightly. Do not exceed 5 caplets nightly. Intended for occasional sleeplessness.
Warnings & Precautions
Precautions re: Allergies
Contains: Wheat
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Consult a healthcare provider if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.
Precautions re: Children
Warning: Consult a healthcare provider if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.
Precautions re: All Other
Do not drive or operate machinery when taking melatonin.
Precautions re: Pregnant or Nursing or Prescription Medications
This product may be contraindicated for individuals taking corticosteroids.
Precautions re: Children
Keep out of reach of children.
Precautions re: All Other
Do not use if blister is torn or ripped or if there is any other evidence of tampering.
Precautions re: Allergies
Contains a bioengineered food ingredient.
Storage
Storage
Store in a cool, dry place.
Formulation
Formula re: Contains
Trouble sleeping? As we age and lead busier lives, our bodies produce less melatonin, the key ingredient we need to fall asleep and stay asleep. REMfresh, made with 99% ultrapure UltraMel melatonin, helps support the body's own natural levels of melatonin for up to 7 hours. The REMfresh advantage Only REMfresh has the breakthrough melatonin IPP (Ion-Powered Pump) technology that promotes continuous release and absorption, allowing you to sleep longer and wake up ready to conquer the day.
Formulation re: Other
REMfresh 7 hour absorption, known as the MESA-WAVE, has been shown in a clinical trial.
Formulation re: Other
Clinically tested
Formula re: Contains
Advanced ion-powered melatonin
Formulation re: Other
7 hour absorption Fall asleep faster Stay asleep longer Improve sleep quality Wake up REfreshed
Formula re: Contains
REMfresh 2 mg UltraMel melatonin
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
For illustrative purposes only. #1 Sleep doctor recommended Among primary care physicians with a certification in sleep disorders who recommended a non-prescription sleep aid brand. IQVIA ProVoice 2020 survey
Brand IP Statement(s) re: (c), (TM), (SM)
REMfresh is protected by U.S. patents No.: 8,691,275; 9,186,351; 9,241,926; 9,549,900; 10,226,447; 10,751,323.
General Statements: All Other Content
Questions/comments: Call us toll free 1-866-554-7071 Or visit www.REMfresh.com REM Absorption Kinetics Trial (REMAKT), a pharmacokinetic trial of 5 mg REMfresh, not a sleep study. Approved after peer review and then published in Primary Care Companion for CNS Disorders, 2019. Individual results may vary.
Brand IP Statement(s) re: (c), (TM), (SM)
All trademarks are owned by Societe des Produits Nestle S.A., Vevey, Switzerland. Copyright 2022 Nestle.
General Statements: All Other Content
Vista Color
Manufacturer & Distributor
Distributor
Nestle HealthCare Nutrition, Inc.
Bridgewater, NJ, 08807, USA
1-866-554-7071
Market Reference
Re-Fresh Platinum Fresh Smoke Odor Eliminator 4 FL OZ 118ML Non-Aerosol (2x Pieces) | Triple Traders
Triple Traders5.0(6)$14.99RepHresh Vaginal Gel
Target4.1(12000)$20.99Refresh Tears Lubricant Eye Drops Multi-Pack
Syessa4.9(562)$23.99Re-Fresh Vanilla Bean Tea Smoke Odor Eliminator 4 FL OZ 118ML Non-Aerosol (2x Pieces) | Triple Traders
Triple Traders5.0(6)$14.99RepHresh Clean Balance Feminine Freshness 2-Step Kit
Instacart4.7(27)$7.17LowestRe-Fresh Smoke Odor Eliminator Spray 4 oz
Triple Traders$14.99Refresh Tears Lubricant Eye Drops
Fleet Farm4.6(4200)$11.99Refresh Optive Mega-3 PF Lubricant Eye Drops
Walmart4.5(61)$19.18
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
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Great Nutrition
5.0 (13)Vitamin & supplements store
1754 E 174th St, Bronx, NY 10472
Pills R us
5.0 (1)Health food store
1690 Vyse Ave, Bronx, NY 10460
GNC
4.3 (75)Vitamin & supplements store
961 E 174th St Unit B-160, Bronx, NY 10460
Parkchester Nutrition Club
4.9 (19)Vitamin & supplements store
1916 Benedict Ave, Bronx, NY 10462
NutriShop
4.8 (83)Vitamin & supplements store
1601 Williamsbridge Rd, Bronx, NY 10461
SWEET NUTRITION
5.0 (6)Vitamin & supplements store
610 Union Ave, Bronx, NY 10455
The Vitamin Shoppe
4.5 (201)Vitamin & supplements store
818 Pelham Pkwy, Pelham, NY 10803
PuraSalus
Vitamin & supplements store
1300 Needham Ave, Bronx, NY 10469
Research & Studies
… , CLINICAL PHARMACOKINETICS EVALUATION OF AN ION POWERED PUMP MELATONIN DELIVERY SYSTEM IN HEALTHY NON-SMOKING ADULTS
DC Brodner, SM Shah - Sleep, 2017 - search.proquest.com
… The IPP-melatonin (ion powered pump melatonin delivery system; REMfresh) was developed to provide an exogenous melatonin pharmacokinetic (PK) profile that mimics normal …
20171 citations0388 CLINICAL EVALUATION OF THE ION POWERED PUMP (IPP) MELATONIN DELIVERY SYSTEM
DC Brodner, SM Shah - Sleep, 2017 - search.proquest.com
… in a regional military healthcare network, focusing on the … Melatonin supplementation has been shown to promote and … IPP-melatonin delivery system (REMfresh) was designed to …
2017Exogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity
K Oda, J Danko, E Villasante… - Frontiers in …, 2025 - frontiersin.org
… were enrolled after eligibility/health screening and informed written consent. … REMfresh ® 5mg caplets (Nestle Health Science), an over the counter (OTC) melatonin supplement…
20250394 Effect of Background Noise on Sleep Quality
L Taranto-Montemurro, L Messineo, S Sands… - Sleep, 2017 - researchgate.net
… Assessment of the taped interviews/sessions suggests a high level of skill in these health … The IPP-melatonin (ion powered pump melatonin delivery system; REMfresh) was developed …
201711 citations0471 24-month post marketing safety surveillance data of a novel continuous release and absorption melatonin (CRA-melatonin) delivery system, confirms favorable …
D Brodner, P Corsino - Sleep, 2020 - search.proquest.com
… This RCT examined the efficacy digital CBTI via mobile health app in pregnant women with … Digitally delivered interventions have potential to improve the health of new and expectant …
20201 citations0398 Improvement in Sleep Duration and Maintenance with Ion Powered Continuous Release and Absorption Melatonin in a Cohort of Patients with Chronic Short …
DJ Seiden, DC Brodner, SM Shah - Sleep, 2019 - search.proquest.com
… medicines/dietary supplements, sourcing them through a range of outlets, ie health-food stores, … Methods: Patients who received a sample of CRA-melatonin (Remfresh) from their …
20191 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-07-18. DSLD Label ID: 289154. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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