Berberine®

Non-Nutrient / Non-Botanical

Brand: Purely Optimal

CapsuleNon-Nutrient/Non-BotanicalOn Market

Functions

Blood Sugar Support

Product label for Berberine — Click to view full label

Net Contents

60 Veggie Capsule(s)

Serving Size

2 Capsule(s)

Servings Per Container

Supplement Form

Capsule

Bar Code (UPC/SKU)

X00241WPE3

Product Version

V2R1

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Capsule(s) · 1 per day

Ingredient	Amount Per Serving
Berberine Hydrochloride(Berberis aristata)	1200 mg	—

Not Present

Other Ingredients

CelluloseRice FlourMaltodextrinMagnesium Stearate

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take two (2) capsules once a day. For best results, take 20-30 min before a meal with an 8 fl oz glass of water or as directed by your health care professional.

Warnings & Precautions

Precautions re: All Other

Caution: Do not exceed recommended dose.

Precautions re: Pregnant or Nursing or Prescription Medications

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Precautions re: Children

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Precautions re: All Other

Do not use if safety seal is damaged or missing.

Precautions re: Allergies

Manufactured in a facility that also processes milk, eggs, fish, shellfish, tree nuts, and soybeans.

Storage

Store in a cool, dry place.

Formulation

Formulation re: Other

Professional formulation

Formula re: Contains

Berberis aristata

Formulation re: Other

Supports digestive health Supports immune function Supports glucose metabolism Supports healthy blood sugar levels

Formulation re: Does NOT Contain

Made with non GMO ingredients Gluten free

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Seals/Symbols

Made In The USA With Globally Sourced Ingredients Lab Tested 3rd Party Certified For Purity & Potency

Manufacturer & Distributor

Distributor

Purely Optimal Nutrition Inc.

Seattle, WA, 98121, USA

1-800-738-6018

support@purelyoptimal.com

Market Reference

$11.11 – $71.40· 40 listings

Purely Optimal Premium Berberine Supplement 1200mg
Walmart - Purely Optimal4.6(19)
$11.20
Pure Formulas Berberine Complete 60 Vegetarian Capsules
GoSupps.com4.6(40)
$39.99
Berberine
The Absorption Company
$68.60
Berberine High Strength 1500mg Berberine Supplement with Black Pepper
Desertcart.ae4.2(18)
$22.33
Flat Tummy Berberine Plus Supplement
iHerb4.3(39)
$34.99
Berberine with Ceylon Cinnamon Supplement Liquid Drops + Bitter Melon Extract
eBay - banzuela3315.0(1)
$11.11Lowest
HUM Nutrition Best of Berberine
Target4.3(1700)
$34.99
Piping Rock Berberine HCL Capsules
Walmart - PIPING ROCK HEALTH PRODUCTS, LLC4.7(217)
$26.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Health Cupboard
4.8 (24)
Vitamin & supplements store
3045 N 5th Street Hwy, Reading, PA 19605
Directions (610) 929-4565
The Vitamin Shoppe
4.4 (198)
Vitamin & supplements store
2719 N Meridian Blvd, Broadcasting Square Dr Suite W 3, Reading, PA 19610
Directions (610) 396-1490
REBOOT Your Nutrition
5.0 (5)
Vitamin & supplements store
410 N 6th St, Reading, PA 19601
Directions (347) 531-7770
Trinity Nutrition Center
4.5 (86)
Vitamin & supplements store
92 Commerce Dr, Wyomissing, PA 19610
Directions (610) 556-2021
Good Shape Nutrition
5.0 (1)
Vitamin & supplements store
438 Walnut St first floor, Reading, PA 19601
Directions (610) 750-2063
GNC
4.1 (23)
Vitamin & supplements store
1173 Berkshire Blvd, Reading, PA 19610
Directions (610) 655-9722
Herbalife Five Stars Nutrition
4.6 (30)
Health food restaurant
3316 Plaza Dr, Reading, PA 19605
Directions (484) 869-5109
HERBALIFE HEALTHYLIFE NUTRITION
5.0 (4)
Vitamin & supplements store
UNOS PASOS DE, 5 N 9th St, Penn St, Reading, PA 19601
Directions (610) 451-0614

Research & Studies

Berberine and health outcomes: An umbrella review
Z Li, Y Wang, Q Xu, J Ma, X Li, J Yan… - Phytotherapy …, 2023 - Wiley Online Library
… Berberine is a plant extract widely used in clinical practice. … the association between berberine consumption and health-… the efficacy and safety of berberine from inception to June 30, …
2023115 citations
… of an innovative berberine food‐grade formulation with an ameliorated absorption: In vitro evidence confirmed by healthy human volunteers pharmacokinetic study
G Petrangolini, F Corti, M Ronchi… - Evidence‐Based …, 2021 - Wiley Online Library
… research in order to achieve the best performing formulation. For these reasons, … (OPC) standardized extract (Enovita®) made exclusively with grape seeds from white wine production. …
202128 citations
Berberine and its role in chronic disease
AFG Cicero, A Baggioni - Anti-inflammatory nutraceuticals and chronic …, 2016 - Springer
… in purely experimental models [137]. Of particular interest is the potential antidepressant effect of berberine. … However, at the best of our knowledge, there are no available data on the …
2016365 citations
Sex‐Dependent Effects of CYP2D6 on the Pharmacokinetics of Berberine in Humans
JA Blöcher, MJ Meyer‐Tönnies, F Morof… - Clinical …, 2025 - Wiley Online Library
… berberine metabolism, but exclusively in females. Females who were poor CYP2D6 metabolizers had an 80% lower M1-to-berberine ratio. … To the best of our knowledge, with 44 healthy …
202513 citations
Berberine and health outcomes: an overview of systematic reviews
L Shi, W Wang, C Jing, J Hu, X Liao - BMC Complementary Medicine and …, 2025 - Springer
… berberine has not been summarized. We aimed to synthesize the current evidence on the systematic review (SRs) of berberine … To the best of our knowledge, the current overview is the …
202524 citations
Effect of food on the oral bioavailability of berberine and monacolin administered in combination in healthy male volunteers
S Persiani, F Sala, M Zangarini, C Manzotti… - Journal of Pharmacy …, 2014 - academia.edu
… In the aeronautical industry, energy generation relies almost exclusively in the combustion of hydrocarbons. The best way to improve the efficiency of such systems, while controlling …
20145 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-07-18. DSLD Label ID: 295273. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.