Melatonin 20 mg®
Non-Nutrient / Non-BotanicalBrand: Pure Encapsulations
Net Contents
180 Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
180
Supplement Form
Capsule
Bar Code (UPC/SKU)
7 66298 00812 7
Product Version
code: ME21 v2.3
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| Melatonin | 20 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule daily, 1/2 to 1 hour before bedtime.
Warnings & Precautions
Precautions re: All Other
Tamper resistant: Use only if safety seal is intact.
Precautions re: All Other
Warning: See side panel.
Precautions re: Children
Keep out of the reach of children.
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Pregnant or nursing women, those with a medical condition, and those taking medication should consult a healthcare professional before use.
Precautions re: All Other
May have sedating effects and is for bedtime use only. Do not drive or operate machinery when taking melatonin. Consumption with alcohol is not recommended. Intended for occasional sleep disturbances or jet lag; for use beyond 4 weeks, consult a healthcare professional.
Precautions re: Pregnant or Nursing or Prescription Medications
This product may be contraindicated in depression, seasonal affective disorder, schizophrenia, autoimmune disease, asthma and for individuals taking MAO inhibitors or corticosteroids.
Precautions re: Children
This product is not intended for children.
Storage
Storage
Store sealed in a cool dry area
Formulation
Formulation re: Does NOT Contain
Commitment to Quality Program Sourced and manufactured to avoid: Artificial Additives Allergens GMOs Environmental Contaminants Added excipients www.PureEncapsulations.com/QualityControl See Ingredients Panel for more information
Formulation re: Other
Hypoallergenic
FDA Statements
FDA Statement of Identity
Dietary Supplement
Manufacturer & Distributor
Manufacturer
Pure Encapsulations, Inc.
490 Boston Post Rd., Sudbury, MA, 01776, USA
Market Reference
Pure Encapsulations Melatonin 20 mg 60 Capsules
Pure For You4.6(134)$39.00Pure Encapsulations Melatonin-SR 60 Capsules
Walmart - Pattern4.7(103)$11.50Pure Encapsulations - Melatonin 20 mg. - 180 Capsules 20mg
Pure Prescriptions4.6(134)$39.00Pure Encapsulations Melatonin, 60 capsules
vitalabo.com4.7(13)$26.12Pure Encapsulations Pure Sleep 60 Capsules
Herbs Direct3.3(3)$52.00Melatonin 20mg by Pure Encapsulations
Cincinnati Health Institute4.7(170)$39.00Pure Encapsulations Melatonin 20 mg
Hasan Mirza, MD4.6(134)$39.00Best Rest Formula Pure Encapsulations
Supplement First4.3(162)$37.00
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.3 (183)Vitamin & supplements store
12 4th Ave, Brooklyn, NY 11217
GNC
4.0 (224)Vitamin & supplements store
134-136 Fulton St, New York, NY 10038
GNC
4.4 (88)Vitamin & supplements store
753 Broadway Spc 753, New York, NY 10003
Pure Essentials Supplements
5.0 (1)Vitamin & supplements store
121 Varick St, New York, NY 10013
The Vitamin Shoppe
3.9 (84)Vitamin & supplements store
32 Court St, Brooklyn, NY 11201
GNC
4.7 (197)Vitamin & supplements store
2 Pennsylvania Plaza Ste 29B, New York, NY 10121
The Vitamin Shoppe
4.4 (98)Vitamin & supplements store
257 8th Ave, New York, NY 10011
GNC
3.6 (101)Vitamin & supplements store
2 Broadway, New York, NY 10004
Research & Studies
Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements
DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
… Due to the interest in immune health prompted by the pandemic and its lasting effects on mental health and sleep disturbances, melatonin (N-acetyl-5-methoxytryptamine) has become …
2022215 citationsMelatonin-loaded nanocarriers: New horizons for therapeutic applications
LGA Chuffa, FRF Seiva, AA Novais, VA Simão… - Molecules, 2021 - mdpi.com
… Randomized double-blinded healthy volunteers (n=14) tested the efficacy of … melatonin orally administered at doses of 5, 10, and 20 mg/kg prior to LPS induction. The load of melatonin …
202167 citationsIon-Triggered In Situ Gel Combined with Melatonin Liposomes: Breaking Through the Dual Barriers of Nasal and Brain Delivery to Treat Insomnia
Z Dong, X Dong, H Wang, Y Pan, M Yang, S Zhao… - Pharmaceutics, 2026 - mdpi.com
2026Effects of absorption kinetics on the catabolism of melatonin released from CAP-coated mesoporous silica drug delivery vehicles
I Moroni, AE Garcia-Bennett - Pharmaceutics, 2021 - mdpi.com
… doses that vary from 1.99 mg (REMfresh ® [8]) to 20 mg (Nutricology ® ). Melatonin can be purchased both as over-the-counter products and with a medical prescription, but its efficacy …
20216 citationsA Series of Personalized Melatonin Supplement Interventions for Poor Sleep: Feasibility Randomized Crossover Trial for Personalized N-of-1 Treatment
MJ Butler, T Chandereng, H Ahn, S Slotnick… - JMIR Formative …, 2025 - formative.jmir.org
… with potential serious health consequences. Exogenous melatonin supplements have been … and placebo doses were provided for this study by Pure Encapsulations LLC, a National …
20254 citationsPreparation, characterization and in vitro evaluation of melatonin-loaded porous starch for enhanced bioavailability
Y Li, X Zhao, L Wang, Y Liu, W Wu, C Zhong… - Carbohydrate …, 2018 - Elsevier
The present work aimed to apply porous starch (PS) as carrier to improve the oral bioavailability of poorly soluble drug melatonin (MLT). The drug loading and encapsulation efficiency …
201851 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-05-22. DSLD Label ID: 219672. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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