Brand: Pure Encapsulations

CapsuleOn Market
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Net Contents

60 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00813 4

Product Version

Not specified

Suggested Use

Recommendations: As a dietary supplement; take 1 capsule daily; 1/2 to 1 hour before bedtime.

Market Reference

$9.75 – $100.00· 23 listings
  • Pure Encapsulations Melatonin 20 mg 60 Capsules

    Walmart - Pattern4.6(134)
    $100.00
  • Pure Encapsulations Melatonin-SR 60 Capsules

    Target4.7(103)
    $11.50
  • Pure Encapsulations - Melatonin 20 mg. - 180 Capsules 20mg

    Pure Prescriptions4.6(134)
    $39.00
  • Pure Encapsulations Melatonin, 60 capsules

    vitalabo.com4.7(13)
    $26.07
  • Pure Encapsulations Pure Sleep 60 Capsules

    Herbs Direct3.3(3)
    $52.00
  • Melatonin 20mg by Pure Encapsulations

    Cincinnati Health Institute4.7(170)
    $39.00
  • Pure Encapsulations Melatonin 20 mg

    Hasan Mirza, MD4.6(134)
    $39.00
  • Best Rest Formula Pure Encapsulations

    Supplement First4.3(162)
    $37.00

Where to Buy Locally

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Research & Studies

  • Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

    DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com

    … Due to the interest in immune health prompted by the pandemic and its lasting effects on mental health and sleep disturbances, melatonin (N-acetyl-5-methoxytryptamine) has become …

    2022215 citations
  • Melatonin-loaded nanocarriers: New horizons for therapeutic applications

    LGA Chuffa, FRF Seiva, AA Novais, VA Simão… - Molecules, 2021 - mdpi.com

    … Randomized double-blinded healthy volunteers (n=14) tested the efficacy of … melatonin orally administered at doses of 5, 10, and 20 mg/kg prior to LPS induction. The load of melatonin …

    202167 citations
  • Ion-Triggered In Situ Gel Combined with Melatonin Liposomes: Breaking Through the Dual Barriers of Nasal and Brain Delivery to Treat Insomnia

    Z Dong, X Dong, H Wang, Y Pan, M Yang, S Zhao… - Pharmaceutics, 2026 - mdpi.com

    2026
  • Effects of absorption kinetics on the catabolism of melatonin released from CAP-coated mesoporous silica drug delivery vehicles

    I Moroni, AE Garcia-Bennett - Pharmaceutics, 2021 - mdpi.com

    … doses that vary from 1.99 mg (REMfresh ® [8]) to 20 mg (Nutricology ® ). Melatonin can be purchased both as over-the-counter products and with a medical prescription, but its efficacy …

    20216 citations
  • A Series of Personalized Melatonin Supplement Interventions for Poor Sleep: Feasibility Randomized Crossover Trial for Personalized N-of-1 Treatment

    MJ Butler, T Chandereng, H Ahn, S Slotnick… - JMIR Formative …, 2025 - formative.jmir.org

    … with potential serious health consequences. Exogenous melatonin supplements have been … and placebo doses were provided for this study by Pure Encapsulations LLC, a National …

    20254 citations
  • Preparation, characterization and in vitro evaluation of melatonin-loaded porous starch for enhanced bioavailability

    Y Li, X Zhao, L Wang, Y Liu, W Wu, C Zhong… - Carbohydrate …, 2018 - Elsevier

    The present work aimed to apply porous starch (PS) as carrier to improve the oral bioavailability of poorly soluble drug melatonin (MLT). The drug loading and encapsulation efficiency …

    201851 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-02-25. DSLD Label ID: 184638. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.