Joint Mediator®

Other Combinations

Brand: Pure Encapsulations

CapsuleOther CombinationsOn Market

Functions

Click to view full label

Net Contents

180 Capsule(s)

Serving Size

3 Capsule(s)

Servings Per Container

60

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 01258 2

Product Version

code: JO11 v6

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

3Active Ingredients

3 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

1% Daily Value Coverage

1 ingredients report an established %DV per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Shellfish

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 3 Capsule(s) · 1–2 per day

IngredientAmount Per Serving% Daily Value
Vitamin D(Cholecalciferol, Vitamin D3)15 mcg75%
Glucosamine Sulfate(Crab, Shrimp)750 mg
Proprietary Blend910 mg
Indian Frankincense (Boswellia serrata) extract(Boswellic Acids)
Turmeric (Curcuma longa) extract(Curcuminoids)
L-Glutamine
Bromelain

Not Present

Other Ingredients

Vegetarian CapsuleAscorbyl Palmitate

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 3 capsules in the morning and 3 capsules in the evening, with meals, with 8-10 oz water.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Precautions re: Allergies

Do not take if you are sensitive to shellfish.

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Use only if safety seal is intact.

Precautions re: Allergies

Contains shellfish (crab, shrimp)

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formulation re: Does NOT Contain

Gluten-free & Non-GMO

Formula re: Contains

Contains shellfish (crab, shrimp)

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Individual results may vary.

General Statements: All Other Content

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

General Statements: All Other Content

Scan to learn about our hypoallergenic supplements

General Statements: All Other Content

Supports healthy joint function and comfort

Seals/Symbols

GF

General: Product/Version Code

v6 code: JO11

Manufacturer & Distributor

Manufacturer

Pure Encapsulations

490 Boston Post Road, Sudbury, MA

1-800-753-2277

Market Reference

$10.00 – $184.00· 38 listings
  • Pure Encapsulations Joint Complex Single Dose 30 Capsules

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  • Glucosamine Chondroitin with MSM Pure Encapsulations

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    $41.50
  • Pure Encapsulations Glucosamine MSM 180 Capsules

    Vitacost.com5.0(9)
    $101.00
  • Pure Encapsulations Glucosamine + Chondroitin with Manganese 120 Capsules

    Walmart - Pattern5.0(7)
    $79.00
  • Ligament Restore Pure Encapsulations

    PureFormulas.com4.6(38)
    $74.00
  • Pure Encapsulations Glucosamine HCl Chondroitin 120 Capsules

    Supplement First4.8(13)
    $85.50
  • Pure Encapsulations Phyto 4 60 Capsules

    Pure For You4.9(17)
    $49.50
  • Move Free Ultra

    CVS Pharmacy4.6(6400)
    $28.63

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Evolve Supplements & Nutrition

    5.0 (16)

    Vitamin & supplements store

    183 Park Ave, East Rutherford, NJ 07073

  • A-1 Nutrition Store

    4.8 (101)

    Vitamin & supplements store

    210 Main Ave, Passaic, NJ 07055

  • GNC

    4.4 (200)

    Vitamin & supplements store

    1057 Bloomfield Ave Store 11, Clifton, NJ 07012

  • CENTRE NUTRITION & WELLNESS

    4.6 (19)

    Vitamin & supplements store

    379 Centre St, Nutley, NJ 07110

  • Unlimited Power Nutrition

    5.0 (1)

    Vitamin & supplements store

    381 Monroe St piso 1, Passaic, NJ 07055

  • Tsunami Nutrition S.r.l.

    3.3 (58)

    Vitamin & supplements store

    Via Marcandreola, 5, 00043 Ciampino RM, Italy

  • Nutrist Health

    Vitamin & supplements store

    630 Bloomfield Ave, Clifton, NJ 07012

  • NutraSol Natural Center

    4.9 (185)

    Vitamin & supplements store

    1139a Main Ave, Clifton, NJ 07011

Research & Studies

  • Cartilage-affinity tea polyphenol liposomes alleviate osteoarthritis by suppressing the PI3K/Akt signaling pathway

    Y Pu, J Zhao, J Lou, T Jin, H Zhao, W Wang - Materials & Design, 2026 - Elsevier

    … pathways, indicating that it is a key mediator of Tp activity. We further confirmed both in … the joint cavity. In our study, LipTp-T demonstrated enhanced inhibition of inflammatory mediators …

    2026
  • Ultra‐Long‐Term Anti‐Inflammatory Polyphenol Capsule to Remodel the Microenvironment for Accelerating Osteoarthritis Healing by Single Dosage

    S Wei, Z Shou, D Yang, L Sun, Y Guo… - Advanced …, 2024 - Wiley Online Library

    … Then, the bone joints of mice were removed, and only the upper and lower joint heads and joint … The levels of inflammatory factors in the joints were also assessed, and IL-6, TNF-α, and …

    202415 citations
  • Curcumin co-encapsulation potentiates anti-arthritic efficacy of meloxicam biodegradable nanoparticles in adjuvant-induced arthritis animal model

    B Aslam, A Hussain, MN Faisal, ZD Sindhu, RU Khan… - Biomedicines, 2023 - mdpi.com

    … The release of numerous inflammatory mediators is critical in the development of pain, joint … joint, which may be associated with a decrease in the production of inflammatory mediators. …

    202320 citations
  • A PRO-RESOLVING LIPID MEDIATOR FOR THE ATTENUATION OF OSTEOARTHRITIS PATHOLOGY

    E Sverdrup - 2025 - scholarsbank.uoregon.edu

    … ∼27 million people with healthcare costs that exceed $185 billion … supplement endogenously produced specialized pro-resolving mediators and control the immune response after joint …

    2025
  • Efficacy and mechanisms of curcumin in the treatment of osteoarthritis: A scoping review

    X Ma, W Zhao, F Yang, KY Chin - Biomolecules and …, 2024 - pmc.ncbi.nlm.nih.gov

    … mechanisms through which curcumin may enhance joint health and mitigate the onset of OA … inflammatory cells into the joint and the release of inflammatory mediators, thus alleviating …

    202412 citations
  • Drug delivery strategies and nanozyme technologies to overcome limitations for targeting oxidative stress in osteoarthritis

    JL Aldrich, A Panicker, R OvalleJr… - …, 2023 - search.proquest.com

    … be just as detrimental to joint health as an overabundance [31]. It … function is detrimental to joint health. This overproduction may be … mediators (IL-1β, IL6) in serum and may prevent joint …

    202338 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-01-07. DSLD Label ID: 182967. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.