Indole-3-Carbinol 400 mg®

Non-Nutrient / Non-Botanical

Brand: Pure Encapsulations

CapsuleNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

120 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

120

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00527 0

Product Version

code: I341 v6

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1–2 per day

IngredientAmount Per Serving
Indole-3-Carbinol400 mg

Not Present

Other Ingredients

Vegetarian Capsulehypoallergenic Plant Fiber

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1–2 times daily, with meals.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Use only if safety seal is intact.

Storage

Storage

Keep refrigerated

Formulation

Formulation re: Does NOT Contain

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formulation re: Does NOT Contain

Gluten-free, Non-GMO & Hypoallergenic

Formulation re: Other

Gluten-free, Non-GMO & Hypoallergenic

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

General Statements: All Other Content

Scan to learn about our hypoallergenic supplements

General Statements: All Other Content

Supports cellular health

Seals/Symbols

GF

General: Product/Version Code

v6 code: I341

Manufacturer & Distributor

Manufacturer

Pure Encapsulations

490 Boston Post Road, Sudbury, MA

1-800-753-2277

Market Reference

$19.79 – $173.50· 10 listings
  • Pure Encapsulations Indole 3 Carbinol mg

    Blue Sky Vitamin4.7(39)
    $68.50
  • Indole-3-Carbinol 400mg

    personalpower
    $68.50
  • Indole-3-carbinol 400mg 120 Vegeterian Capsules for Hormone Balance & Cellular Health

    Walmart - LongLifeNutri
    $29.30
  • Life Extension Indole 3-Carbinol with DIM Capsules

    Life Extension4.4(8)
    $24.99
  • Carlyle Indole 3-Carbinol 400mg 120 Capsules

    Walmart - Carlyle Nutritionals, LLC4.7(18)
    $19.79Lowest
  • Metagenics Indole-3-Carbinol for Hormone Balance

    Pure Prescriptions
    $38.95
  • Indole-3-carbinol

    aobious.com
    $25.00
  • 60 vegcaps

    Curated Wellness4.7(39)
    $68.50

Where to Buy Locally

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    4.9 (480)

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    Suite 1000, 405 King's Rd, London SW10 0BB

  • The Formula Supplements Ltd

    5.0 (1)

    Health food shop

    128 City Rd, London EC1V 2NX

Research & Studies

  • Target-based Antidiabetic Indole Derivatives and Insights into Structure-activity Relationships: A Mechanistic Update 2020-2025

    A Wal, P Wal, A Gupta, G Hemalatha… - Current Drug …, 2026 - benthamdirect.com

    … Endogenous and dietary indoles such as melatonin and indole-3-carbinol play roles in … Indole-3-carbinol derivatives significantly increase IRS-1 activity, and N1-alkylated indoles …

    2026
  • Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals

    LM Howells, EP Moiseeva, CP Neal… - Acta …, 2007 - search.proquest.com

    … of the best studied agents (indole-3-carbinol, diindolylmethane, curcumin, epigallocatechin-3-… in healthy human volunteers via the oral administration of either resveratrol in its pure form …

    2007150 citations
  • Natural compounds targeting MAPK, PI3K/Akt, and JAK/STAT signaling in papillary thyroid cancer

    C Michelle, N Yang, RK Tiwari… - … journal of molecular …, 2025 - search.proquest.com

    … bioactive dimer derived from the endogenous conversion of indole-3-carbinol (I3C) [70]. I3C … that has demonstrated many potential health benefits including cardioprotective, antioxidant…

    202510 citations
  • Effects of phytochemicals on cellular signaling: reviewing their recent usage approaches

    DC Pham, MA Shibu, B Mahalakshmi… - Critical reviews in …, 2020 - Taylor & Francis

    … Maintaining a sustainable health in the society has always … Better conceptions on health, diseases and remedies have … of six phytochemicals (indole-3-carbinol, resveratrol, genistein …

    202079 citations
  • Natural products for the prevention, treatment and progression of breast cancer

    F Svolacchia, S Brongo, A Catalano, A Ceccarini… - Cancers, 2023 - mdpi.com

    … effects and may also damage healthy tissues and organs. In … BC and classic surgical and medical therapy in order to reduce … gallate (EGCG), indole-3-carbinol (I3C), artesunate, ginger, …

    202324 citations
  • Natural supplements in breast cancer therapy: translational evidence, clinical safety, and emerging challenges

    S Talath, M El-Tanani, AF Wali, SA Rabbani… - Frontiers in …, 2026 - frontiersin.org

    … The increasing demand for natural supplements and other … by more comprehensive methods of health care that aim to … Indole-3-carbinol (I3C) and its metabolite DIM exert hormone…

    2026

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-01-07. DSLD Label ID: 184995. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.