Homocysteine Factors®

Other Combinations

Brand: Pure Encapsulations

CapsuleOther CombinationsOff Market
Click to view full label

Net Contents

60 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

60

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00151 7

Product Version

code: HO6 v8

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

4Active Ingredients

4 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3% Daily Value Coverage

3 ingredients report a %DV; 3 meet or exceed 100% DV.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 2 per day

IngredientAmount Per Serving% Daily Value
Vitamin B6(Pyridoxal 5-Phosphate)25 mg1471%
Folate(Metafolin)667 mcg DFE167%
L-5-MTHF400 mcg
Vitamin B12(Methylcobalamin)200 mcg8333%
Trimethylglycine(Anhydrous Betaine)500 mg

Not Present

Other Ingredients

Vegetarian Capsulehypoallergenic Plant FiberAscorbyl Palmitate

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 2 times daily, with meals.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Use only if safety seal is intact.

Storage

Storage

Refrigerate after opening.

Formulation

Formulation re: Does NOT Contain

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formula re: Contains

With Metafolin L-5-MTHF; Supports healthy homocysteine metabolism

Formulation re: Does NOT Contain

Gluten-free, Non-GMO & Hypoallergenic

Formulation re: Other

Gluten-free, Non-GMO & Hypoallergenic

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

General Statements: All Other Content

Scan to learn about our hypoallergenic supplements

Seals/Symbols

GF

General Statements: All Other Content

Natural color variations can occur. Product can range from off-white to yellow.

Brand IP Statement(s) re: (c), (TM), (SM)

Metafolin is a registered trademark of Merck KGaA, Darmstadt, Germany.

General: Product/Version Code

v8 code: HO6

Manufacturer & Distributor

Manufacturer

Pure Encapsulations

490 Boston Post Road, Sudbury, MA

1-800-753-2277

Market Reference

$20.50 – $107.00· 40 listings
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  • Homocysteine Pearls

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  • Pure Encapsulations - O.N.E. Multivitamin - 120 Capsules

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  • Pure Encapsulations NR Longevity 60 Capsules

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  • 60 Capsules

    Integrative Mental Health4.8(22)
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Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Discount Nutrition

    4.8 (58)

    Vitamin & supplements store

    1544 Piedmont Rd NE Ste 318, Atlanta, GA 30324

  • Health Nut East Point

    5.0 (97)

    Vitamin & supplements store

    3865 Washington Rd, East Point, GA 30344

  • Vita Life Source

    5.0 (1)

    Vitamin & supplements store

    2293 Peachtree Rd, Atlanta, GA 30309

  • Good Nutrition

    4.5 (118)

    Vitamin & supplements store

    2855 N Druid Hills Rd NE, Atlanta, GA 30329

  • Good Nutrition

    4.4 (30)

    Vitamin & supplements store

    155 Hammond Dr G, Sandy Springs, GA 30328

  • Good Nutrition

    4.5 (243)

    Vitamin & supplements store

    2640 Beaver Ruin Rd #C, Norcross, GA 30071

  • Optimal Nutrition & Wellness

    4.6 (10)

    Vitamin & supplements store

    2296 Henderson Mill Rd #405, Atlanta, GA 30345

  • Total Nutrition Atlanta

    4.8 (173)

    Vitamin & supplements store

    6597-G Roswell Rd NE, Sandy Springs, GA 30328

Research & Studies

  • Blood homocysteine and fasting insulin levels are reduced and erythrocyte sedimentation rates increased with a glycophospholipid-vitamin formulation: a …

    RR Ellithorpe, R Settineri, T Ellithorpe… - … Foods in Health and …, 2015 - ffhdj.com

    … The test supplement used in the … test supplement, have been demonstrated to have a modest effect on CHD and stroke [28]. The independent effect of B-vitamins in the test supplement …

    201510 citations
  • Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study

    JJ Ryan, DA Hanes, MB Schafer… - … Integrative Health, 2015 - journals.sagepub.com

    … -CRP, insulin, homocysteine, and fibrinogen did not … Health National Center for Complementary and Alternative Medicine (5R25AT002878). We would like to thank Pure Encapsulations, …

    201557 citations
  • Potential of nanomaterial applications in dietary supplements and foods for special medical purposes

    J Jampilek, J Kos, K Kralova - Nanomaterials, 2019 - mdpi.com

    … hydroxyvitamin D concentrations and reduction of serum homocysteine concentrations suggesting that such treatment could reduce risk factors for CVD and may potentially contribute to …

    2019223 citations
  • Heart-Healthy Diet

    R Kordonowy, D Marconi, M Barry, PP Encapsulations - imlwp.com

    … of homocysteine, … supplements help lower homocysteine levels, they do not protect against heart disease, stroke, or dementia (memory loss). Some researchers think that homocysteine …

  • A comprehensive review of fortification, bioavailability, and health benefits of folate

    J Li, D Hanying, R Hosahalli… - International journal of …, 2025 - search.proquest.com

    … to prevent these health … homocysteine (Hcy) levels, folate levels were also linked to oxidative stress and inflammation [5,6,7]. Consequently, with the growing interest in folate, its health …

    202518 citations
  • Challenges in developing delivery systems for food additives, nutraceuticals and dietary supplements

    MA Augustin, L Sanguansri - Encapsulation technologies and delivery …, 2012 - Elsevier

    This chapter begins with a review of ingredients used as food additives, nutraceuticals and dietary supplements. It describes issues encountered in delivering dietary supplements to …

    201298 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-01-07. DSLD Label ID: 184984. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.