5-HTP (5-Hydroxytryptophan) 50 mg®

Amino Acids & Protein

Brand: Pure Encapsulations

CapsuleAmino acid/ProteinOn Market
Click to view full label

Net Contents

60 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

60

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00153 1

Product Version

code: HYD56 v8

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1–4 per day

IngredientAmount Per Serving
5-HTP50 mg

Not Present

Other Ingredients

Plant FiberCelluloseWater

Target Groups

Adult (18 - 50 Years)Women (not pregnant or lactating)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.

Warnings & Precautions

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Use only if safety seal is intact.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, particularly psychiatric medications, consult your health professional before use. Do not use concurrently with antidepressants.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formulation re: Other

Supports brain serotonin levels

Formulation re: Does NOT Contain

Gluten-free, Non-GMO & hypoallergenic

Formulation re: Other

Gluten-free, Non-GMO & hypoallergenic

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Warning: See side panel.

General Statements: All Other Content

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Manufacturer & Distributor

Manufacturer

Pure Encapsulations

490 Boston Post Road, Sudbury, MA

1-800-753-2277

Market Reference

$5.61 – $67570.00· 40 listings
  • 5-HTP mg Pure Encapsulations

    Target4.8(83)
    $42.50
  • NOW 5-HTP mg

    Walmart - Discount Nutrition Store4.7(14000)
    $13.99
  • Thorne Research 5-HTP

    Thorne4.6(687)
    $39.00
  • Pure Micronutrients Pure 5 HTP Plus GABA Supplement for Sleep

    Pure Micronutrients4.8(64)
    $24.97
  • Pain & Stress Center 5-HTP 5-Hydroxytryptophan 50 mg 60 Capsules

    Walmart - Pain & Stress Center
    $19.95
  • Pure MotilPro Digestive Support 90 Capsules

    PureFormulas.com4.1(275)
    $66.00
  • 5-HTP 50mg

    Pure Prescriptions
    $29.99
  • Solaray 5-HTP

    Optimist4.3(28)
    $9.71

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Gymstore Xã Đàn

    4.8 (328)

    Vitamin & supplements store

    398 P. Xã Đàn, Văn Miếu - Quốc Tử Giám, Hà Nội, Vietnam

Research & Studies

  • 5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology

    ME Maffei - International journal of molecular sciences, 2020 - mdpi.com

    … This review describes the natural sources of 5-HTP, which represent the raw material from which 5-HTP may be extracted and purified for its use in drugs and dietary supplements, as …

    2020329 citations
  • Construction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo

    L Gao, L Gu, W Li, G Wang, J Zhao, W Chen… - International Journal of …, 2025 - Elsevier

    … 5-Hydroxytryptophan (5-HTP) is a functional food ingredient … for the encapsulation and sustained release of 5-HTP. The … profile and distribution of 5-HTP in rats, including serum, gut, …

    20255 citations
  • Guest-host relationship of cyclodextrin and its pharmacological benefits

    F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com

    … was in the order SBEβ-CD:5HTP> HPβ-CD:5-HTP> β-CD:5-HTP> 5-HTP, as the percentage cell … complexes of βcyclodextrins and 5-hydroxytryptophan: Enhancement of water solubility, …

    202322 citations
  • Migraine headaches: opportunities for management with precision nutrition

    BI Brown - Nutritional Med J, 2022 - nmi.health

    … 5-HTP (5 mg per kg of body weight daily) when compared with placebo.However, it should be noted that both 5-HTP … by an unrestricted donation from Pure Encapsulations, Sudbury, MA…

    20224 citations
  • Flavonoids improve neurotransmitters for Parkinson's treatment: mechanism and therapeutic potential

    Y Zhang, Y Bu, M Song, Z Hao, J Chen - Frontiers in Pharmacology, 2026 - frontiersin.org

    Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder worldwide, and it stands out as one of the neurological conditions exhibiting the …

    2026
  • The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT

    C Evans, V Mekhail, J Curtis, P Czartoryski… - … Dietary Supplements, 2023 - Taylor & Francis

    … The purpose of this investigation was to determine the effects of supplementing with 100 mg daily of 5-Hydroxytryptophan (5-HTP) on indices of body composition in exercise-trained …

    202310 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-05-24. DSLD Label ID: 293866. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.