5-HTP (5-Hydroxytryptophan) 50 mg®

Amino Acids & Protein

Brand: Pure Encapsulations

CapsuleAmino acid/ProteinOff Market
Click to view full label

Net Contents

180 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

180

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00154 8

Product Version

code: HYD51 v5.3

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Capsule(s) · 1–4 per day

IngredientAmount Per Serving
5-HTP50 mg—

Not Present

Other Ingredients

hypoallergenic Plant FiberVegetarian Capsule

Target Groups

Adult (18 - 50 Years)Women (not pregnant or lactating)

Label Claims

All Other

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.

Warnings & Precautions

Precautions re: All Other

Tamper Resistant: Use only if safety seal is intact.

Precautions re: All Other

Warning: See side panel.

Precautions re: Children

Keep out of the reach of children.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Do not use con-currently with SSRI medications or MAO inhibitors.

Storage

Storage

Store sealed in a cool dry area

Formulation

Formulation re: Does NOT Contain

Commitment to Quality Program Sourced and manufactured to avoid: Artificial additives Allergens GMOs Environmental contaminants Added excipients www.PureEncapsulations.com/QualityControl See supplement facts for specific product details

Formulation re: Other

Hypoallergenic

FDA Statements

FDA Statement of Identity

Dietary Supplement

Manufacturer & Distributor

Manufacturer

Pure Encapsulations, Inc.

Sudbury, MA, USA

1-800-753-2277

Market Reference

$5.61 – $60.00· 40 listings
  • 5-HTP mg Pure Encapsulations

    Pure Prescriptions4.8(83)
    $42.50
  • Best Naturals 5-HTP mg 120 Capsules

    Target4.6(197)
    $9.99
  • BulkSupplements.com 5-HTP Capsules 5-Hydroxytryptophan Amino Acid Supplement

    Walmart - BulkSupplements.com4.8(823)
    $20.97
  • NOW Foods 5-HTP 50 mg 30 Capsules

    Walmart - iHerb4.7(2700)
    $5.61Lowest
  • PureFormulas 5 HTP Complete 90 Capsules

    PureFormulas.com4.7(21)
    $26.39
  • Jarrow Formulas 5-HTP 100 mg 60 Capsules

    Pure Prescriptions4.7(454)
    $24.99
  • 5-HTP Source Naturals

    Smallflower.com4.7(227)
    $10.00
  • Thorne Research 5-HTP

    Wellness Pharmacy4.6(687)
    $39.00

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Holland & Barrett - Dalston Cross

    3.3 (40)

    Vitamin & Supplements Shop

    Unit 2B, Kingsland Shopping Centre, Kingsland High St, London E8 2LX

  • Power Up Supplement

    4.9 (431)

    Vitamin & Supplements Shop

    601 Lea Bridge Rd, London E10 6AJ

  • Holland & Barrett - Islington

    3.7 (44)

    Vitamin & Supplements Shop

    212 Upper St, London N1 1RL

  • London Supplements

    3.7 (84)

    Vitamin & Supplements Shop

    13, Waverley Industrial Park Waverley Industrial Estate, Hailsham Dr, Harrow HA1 4TR

  • Holland & Barrett - Hackney

    3.8 (48)

    Vitamin & Supplements Shop

    376 Mare St, London E8 1HR

  • Holland & Barrett - Angel Islington

    3.8 (79)

    Vitamin & Supplements Shop

    21-22 Upper St, London N1 0PQ

  • Holland & Barrett - Holloway Road

    3.5 (79)

    Vitamin & Supplements Shop

    416-418 Holloway Rd, London N7 6QD

Research & Studies

  • 5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology

    ME Maffei - International journal of molecular sciences, 2020 - mdpi.com

    … This review describes the natural sources of 5-HTP, which represent the raw material from which 5-HTP may be extracted and purified for its use in drugs and dietary supplements, as …

    2020329 citations
  • Construction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo

    L Gao, L Gu, W Li, G Wang, J Zhao, W Chen… - International Journal of …, 2025 - Elsevier

    … 5-Hydroxytryptophan (5-HTP) is a functional food ingredient … for the encapsulation and sustained release of 5-HTP. The … profile and distribution of 5-HTP in rats, including serum, gut, …

    20255 citations
  • Guest-host relationship of cyclodextrin and its pharmacological benefits

    F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com

    … was in the order SBEβ-CD:5HTP> HPβ-CD:5-HTP> β-CD:5-HTP> 5-HTP, as the percentage cell … complexes of βcyclodextrins and 5-hydroxytryptophan: Enhancement of water solubility, …

    202322 citations
  • Migraine headaches: opportunities for management with precision nutrition

    BI Brown - Nutritional Med J, 2022 - nmi.health

    … 5-HTP (5 mg per kg of body weight daily) when compared with placebo.However, it should be noted that both 5-HTP … by an unrestricted donation from Pure Encapsulations, Sudbury, MA…

    20224 citations
  • Flavonoids improve neurotransmitters for Parkinson's treatment: mechanism and therapeutic potential

    Y Zhang, Y Bu, M Song, Z Hao, J Chen - Frontiers in Pharmacology, 2026 - frontiersin.org

    Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder worldwide, and it stands out as one of the neurological conditions exhibiting the …

    2026
  • The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT

    C Evans, V Mekhail, J Curtis, P Czartoryski… - … Dietary Supplements, 2023 - Taylor & Francis

    … The purpose of this investigation was to determine the effects of supplementing with 100 mg daily of 5-Hydroxytryptophan (5-HTP) on indices of body composition in exercise-trained …

    202310 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-04-23. DSLD Label ID: 218675. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.