5-HTP (5-Hydroxytryptophan) 50 mg®
Amino Acids & ProteinBrand: Pure Encapsulations
Net Contents
180 Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
180
Supplement Form
Capsule
Bar Code (UPC/SKU)
7 66298 00154 8
Product Version
code: HYD51 v5.3
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Capsule(s) · 1–4 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| 5-HTP | 50 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.
Warnings & Precautions
Precautions re: All Other
Tamper Resistant: Use only if safety seal is intact.
Precautions re: All Other
Warning: See side panel.
Precautions re: Children
Keep out of the reach of children.
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Do not use con-currently with SSRI medications or MAO inhibitors.
Storage
Storage
Store sealed in a cool dry area
Formulation
Formulation re: Does NOT Contain
Commitment to Quality Program Sourced and manufactured to avoid: Artificial additives Allergens GMOs Environmental contaminants Added excipients www.PureEncapsulations.com/QualityControl See supplement facts for specific product details
Formulation re: Other
Hypoallergenic
FDA Statements
FDA Statement of Identity
Dietary Supplement
Manufacturer & Distributor
Manufacturer
Pure Encapsulations, Inc.
Sudbury, MA, USA
1-800-753-2277
Market Reference
5-HTP mg Pure Encapsulations
Pure Prescriptions4.8(83)$42.50Best Naturals 5-HTP mg 120 Capsules
Target4.6(197)$9.99BulkSupplements.com 5-HTP Capsules 5-Hydroxytryptophan Amino Acid Supplement
Walmart - BulkSupplements.com4.8(823)$20.97NOW Foods 5-HTP 50 mg 30 Capsules
Walmart - iHerb4.7(2700)$5.61LowestPureFormulas 5 HTP Complete 90 Capsules
PureFormulas.com4.7(21)$26.39Jarrow Formulas 5-HTP 100 mg 60 Capsules
Pure Prescriptions4.7(454)$24.995-HTP Source Naturals
Smallflower.com4.7(227)$10.00Thorne Research 5-HTP
Wellness Pharmacy4.6(687)$39.00
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Holland & Barrett - Dalston Cross
3.3 (40)Vitamin & Supplements Shop
Unit 2B, Kingsland Shopping Centre, Kingsland High St, London E8 2LX
Power Up Supplement
4.9 (431)Vitamin & Supplements Shop
601 Lea Bridge Rd, London E10 6AJ
Holland & Barrett - Islington
3.7 (44)Vitamin & Supplements Shop
212 Upper St, London N1 1RL
London Supplements
3.7 (84)Vitamin & Supplements Shop
13, Waverley Industrial Park Waverley Industrial Estate, Hailsham Dr, Harrow HA1 4TR
Holland & Barrett - Hackney
3.8 (48)Vitamin & Supplements Shop
376 Mare St, London E8 1HR
Holland & Barrett - Angel Islington
3.8 (79)Vitamin & Supplements Shop
21-22 Upper St, London N1 0PQ
Holland & Barrett - Holloway Road
3.5 (79)Vitamin & Supplements Shop
416-418 Holloway Rd, London N7 6QD
Research & Studies
5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology
ME Maffei - International journal of molecular sciences, 2020 - mdpi.com
… This review describes the natural sources of 5-HTP, which represent the raw material from which 5-HTP may be extracted and purified for its use in drugs and dietary supplements, as …
2020329 citationsConstruction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo
L Gao, L Gu, W Li, G Wang, J Zhao, W Chen… - International Journal of …, 2025 - Elsevier
… 5-Hydroxytryptophan (5-HTP) is a functional food ingredient … for the encapsulation and sustained release of 5-HTP. The … profile and distribution of 5-HTP in rats, including serum, gut, …
20255 citationsGuest-host relationship of cyclodextrin and its pharmacological benefits
F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com
… was in the order SBEβ-CD:5HTP> HPβ-CD:5-HTP> β-CD:5-HTP> 5-HTP, as the percentage cell … complexes of βcyclodextrins and 5-hydroxytryptophan: Enhancement of water solubility, …
202322 citationsMigraine headaches: opportunities for management with precision nutrition
BI Brown - Nutritional Med J, 2022 - nmi.health
… 5-HTP (5 mg per kg of body weight daily) when compared with placebo.However, it should be noted that both 5-HTP … by an unrestricted donation from Pure Encapsulations, Sudbury, MA…
20224 citationsFlavonoids improve neurotransmitters for Parkinson's treatment: mechanism and therapeutic potential
Y Zhang, Y Bu, M Song, Z Hao, J Chen - Frontiers in Pharmacology, 2026 - frontiersin.org
Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder worldwide, and it stands out as one of the neurological conditions exhibiting the …
2026The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT
C Evans, V Mekhail, J Curtis, P Czartoryski… - … Dietary Supplements, 2023 - Taylor & Francis
… The purpose of this investigation was to determine the effects of supplementing with 100 mg daily of 5-Hydroxytryptophan (5-HTP) on indices of body composition in exercise-trained …
202310 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-04-23. DSLD Label ID: 218675. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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