5-HTP (5-Hydroxytryptophan) 50 mg®
Amino Acids & ProteinBrand: Pure Encapsulations
Net Contents
180 Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
180
Supplement Form
Capsule
Bar Code (UPC/SKU)
7 66298 00154 8
Product Version
code: HYD51 v6
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Capsule(s) · 1–4 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| 5-HTP | 50 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.
Warnings & Precautions
Precautions re: All Other
Warning: See side panel.
Precautions re: Children
Keep out of the reach of children.
Precautions re: All Other
Use only if safety seal is intact.
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, particularly psychiatric medications, consult your health professional before use. Do not use concurrently with antidepressants.
Storage
Storage
Store in a cool, dry place.
Formulation
Formulation re: Does NOT Contain
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Formulation re: Does NOT Contain
Gluten-free, Non-GMO & Hypoallergenic
Formulation re: Other
Gluten-free, Non-GMO & Hypoallergenic
FDA Statements
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Other Label Statements
General Statements: All Other Content
Scan to learn about our hypoallergenic supplements
General Statements: All Other Content
Contents may not fill bottle in order to accommodate required labeling. Please rely on stated quantity.
General Statements: All Other Content
Supports brain serotonin levels
Seals/Symbols
GF
General: Product/Version Code
v6 code: HYD51
Manufacturer & Distributor
Manufacturer
Pure Encapsulations
490 Boston Post Road, Sudbury, MA
1-800-753-2277
Market Reference
5-HTP mg Pure Encapsulations
Pure For You4.8(21)$42.505-HTP by Pure Encapsulations
Cincinnati Health Institute4.8(21)$42.50Pure Encapsulations MotilPro 180 Capsules
Instacart4.1(270)$79.97Pain & Stress Center 5-HTP 5-Hydroxytryptophan 50mg 60 Capsules
Walmart - Pain & Stress Center$9.985-HTP 50mg
Pure Prescriptions4.7(253)$24.995-HTP
Soytopia$32.995-HTP (5-Hydroxytryptophan)
Atlanta Functional Medicine4.7(673)$39.005-HTP 50 mg 60 capsules
Life Extension$21.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
GNC
4.1 (39)Vitamin & supplements store
241 Habersham Village Cir, Cornelia, GA 30531
The Vitamin Shoppe
4.4 (70)Vitamin & supplements store
675 Dawsonville Hwy, Gainesville, GA 30501
Research & Studies
The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
S Li, CN Sutanto, X Xia, JE Kim - Nutrients, 2025 - mdpi.com
… and mental health regulation [21,23,24,25]. Given that the participants in this study were cognitively healthy and had not previously taken 5-HTP supplementation, 100 mg was selected …
20254 citations5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology
ME Maffei - International journal of molecular sciences, 2020 - mdpi.com
… This review describes the natural sources of 5-HTP, which represent the raw material from which 5-HTP may be extracted and purified for its use in drugs and dietary supplements, as …
2020320 citationsFlavonoids improve neurotransmitters for Parkinson's treatment: mechanism and therapeutic potential
Y Zhang, Y Bu, M Song, Z Hao, J Chen - Frontiers in Pharmacology, 2026 - frontiersin.org
Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder worldwide, and it stands out as one of the neurological conditions exhibiting the …
2026Guest-host relationship of cyclodextrin and its pharmacological benefits
F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com
… was in the order SBEβ-CD:5HTP> HPβ-CD:5-HTP> β-CD:5-HTP> 5-HTP, as the percentage cell … complexes of βcyclodextrins and 5-hydroxytryptophan: Enhancement of water solubility, …
202322 citationsMigraine headaches: opportunities for management with precision nutrition
BI Brown - Nutritional Med J, 2022 - nmi.health
… 5-HTP (5 mg per kg of body weight daily) when compared with placebo.However, it should be noted that both 5-HTP … by an unrestricted donation from Pure Encapsulations, Sudbury, MA…
20224 citationsConstruction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo
L Gao, L Gu, W Li, G Wang, J Zhao, W Chen… - International Journal of …, 2025 - Elsevier
… 5-Hydroxytryptophan (5-HTP) is a functional food ingredient … for the encapsulation and sustained release of 5-HTP. The … profile and distribution of 5-HTP in rats, including serum, gut, …
20254 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-01-07. DSLD Label ID: 184580. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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