5-HTP (5-Hydroxytryptophan) 50 mg®

Amino Acids & Protein

Brand: Pure Encapsulations

CapsuleAmino acid/ProteinOff Market
Click to view full label

Net Contents

180 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

180

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00154 8

Product Version

code: HYD51 v6

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1–4 per day

IngredientAmount Per Serving
5-HTP50 mg—

Not Present

Other Ingredients

hypoallergenic Plant FiberVegetarian Capsule

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.

Warnings & Precautions

Precautions re: All Other

Warning: See side panel.

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Use only if safety seal is intact.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, particularly psychiatric medications, consult your health professional before use. Do not use concurrently with antidepressants.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formulation re: Does NOT Contain

Gluten-free, Non-GMO & Hypoallergenic

Formulation re: Other

Gluten-free, Non-GMO & Hypoallergenic

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Scan to learn about our hypoallergenic supplements

General Statements: All Other Content

Contents may not fill bottle in order to accommodate required labeling. Please rely on stated quantity.

General Statements: All Other Content

Supports brain serotonin levels

Seals/Symbols

GF

General: Product/Version Code

v6 code: HYD51

Manufacturer & Distributor

Manufacturer

Pure Encapsulations

490 Boston Post Road, Sudbury, MA

1-800-753-2277

Market Reference

$9.19 – $153.00· 40 listings
  • 5-HTP mg Pure Encapsulations

    Pure For You4.8(21)
    $42.50
  • 5-HTP by Pure Encapsulations

    Cincinnati Health Institute4.8(21)
    $42.50
  • Pure Encapsulations MotilPro 180 Capsules

    Instacart4.1(270)
    $79.97
  • Pain & Stress Center 5-HTP 5-Hydroxytryptophan 50mg 60 Capsules

    Walmart - Pain & Stress Center
    $9.98
  • 5-HTP 50mg

    Pure Prescriptions4.7(253)
    $24.99
  • 5-HTP

    Soytopia
    $32.99
  • 5-HTP (5-Hydroxytryptophan)

    Atlanta Functional Medicine4.7(673)
    $39.00
  • 5-HTP 50 mg 60 capsules

    Life Extension
    $21.99

Where to Buy Locally

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Research & Studies

  • The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial

    S Li, CN Sutanto, X Xia, JE Kim - Nutrients, 2025 - mdpi.com

    … and mental health regulation [21,23,24,25]. Given that the participants in this study were cognitively healthy and had not previously taken 5-HTP supplementation, 100 mg was selected …

    20254 citations
  • 5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology

    ME Maffei - International journal of molecular sciences, 2020 - mdpi.com

    … This review describes the natural sources of 5-HTP, which represent the raw material from which 5-HTP may be extracted and purified for its use in drugs and dietary supplements, as …

    2020320 citations
  • Flavonoids improve neurotransmitters for Parkinson's treatment: mechanism and therapeutic potential

    Y Zhang, Y Bu, M Song, Z Hao, J Chen - Frontiers in Pharmacology, 2026 - frontiersin.org

    Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder worldwide, and it stands out as one of the neurological conditions exhibiting the …

    2026
  • Guest-host relationship of cyclodextrin and its pharmacological benefits

    F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com

    … was in the order SBEβ-CD:5HTP> HPβ-CD:5-HTP> β-CD:5-HTP> 5-HTP, as the percentage cell … complexes of βcyclodextrins and 5-hydroxytryptophan: Enhancement of water solubility, …

    202322 citations
  • Migraine headaches: opportunities for management with precision nutrition

    BI Brown - Nutritional Med J, 2022 - nmi.health

    … 5-HTP (5 mg per kg of body weight daily) when compared with placebo.However, it should be noted that both 5-HTP … by an unrestricted donation from Pure Encapsulations, Sudbury, MA…

    20224 citations
  • Construction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo

    L Gao, L Gu, W Li, G Wang, J Zhao, W Chen… - International Journal of …, 2025 - Elsevier

    … 5-Hydroxytryptophan (5-HTP) is a functional food ingredient … for the encapsulation and sustained release of 5-HTP. The … profile and distribution of 5-HTP in rats, including serum, gut, …

    20254 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-01-07. DSLD Label ID: 184580. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.