5-HTP (5-Hydroxytryptophan) 100 mg®

Amino Acids & Protein

Brand: Pure Encapsulations

CapsuleAmino acid/ProteinOn Market
Click to view full label

Net Contents

180 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

180

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 66298 00379 5

Product Version

code: HYD11 v7

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1–3 per day

IngredientAmount Per Serving
5-Hydroxytryptophan100 mg

Not Present

Other Ingredients

hypoallergenic Plant FiberCelluloseWater

Target Groups

Adult (18 - 50 Years)Women (not pregnant or lactating)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-3 times daily, before meals.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Do not use concurrently with antidepressants.

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Use only if safety seal is intact.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Certified gluten-free by the gluten-free certification organization, www.gluten.org

Formulation re: Other

Supports brain serotonin levels Gluten-free, non-GMO & Hypoallergenic

Formulation re: Does NOT Contain

Gluten-free, non-GMO & Hypoallergenic

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Contents may not fill bottle in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Manufacturer & Distributor

Manufacturer

Pure Encapsulations

490 Boston Post Road, Sudbury, MA

1-800-753-2277

Market Reference

$8.49 – $153.00· 40 listings
  • 5-HTP mg Pure Encapsulations

    Target4.8(83)
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  • Pure Encapsulations 5-HTP 100mg 180 Capsules

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    $153.00
  • GNC 5-HTP 100mg 30 Count Capsules

    GNC4.3(6)
    $26.99
  • Thorne Research 5-HTP

    Thorne4.6(687)
    $39.00
  • Andrew Lessman 5-HTP 100 360 Capsules

    ProCaps Laboratories
    $13.90
  • Pain & Stress Center 5-HTP 5-Hydroxytryptophan 50 mg 60 Capsules

    Walmart - Pain & Stress Center
    $19.95
  • 5-HTP 100mg

    Pure Prescriptions
    $43.99
  • 5-HTP

    Soytopia
    $32.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Supplement Store Beograd

    4.8 (58)

    Vitamin & Supplements Shop

    Kosančićev venac 1, Beograd 11000, Serbia

Research & Studies

  • The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT

    C Evans, V Mekhail, J Curtis, P Czartoryski… - … Dietary Supplements, 2023 - Taylor & Francis

    … the effects of supplementing with 100 mg daily of 5-Hydroxytryptophan (5-HTP) on indices of … (n = 31, 12 male/19 female; 100 mg 5-HTP daily; CLEANMOOD™) or a placebo (n = 17, six …

    202310 citations
  • Guest-host relationship of cyclodextrin and its pharmacological benefits

    F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com

    … was in the order SBEβ-CD:5HTP> HPβ-CD:5-HTP> β-CD:5-HTP> 5-HTP, as the percentage cell … complexes of βcyclodextrins and 5-hydroxytryptophan: Enhancement of water solubility, …

    202322 citations
  • Adjunctive 5-hydroxytryptophan slow-release for treatment-resistant depression: clinical and preclinical rationale

    …, AD Krystal, KRR Krishnan, MG Caron - Trends in …, 2016 - cell.com

    … of 5-hydroxytryptophan (5-HTP) safely elevates 5-HT Ext beyond the SERT inhibitor effect in humans; however, 5-HTP … the pharmacokinetic limitations of 5-HTP, substantially enhancing …

    201699 citations
  • Construction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo

    L Gao, L Gu, W Li, G Wang, J Zhao, W Chen… - International Journal of …, 2025 - Elsevier

    … 5-Hydroxytryptophan (5-HTP) is a functional food ingredient … for the encapsulation and sustained release of 5-HTP. The … profile and distribution of 5-HTP in rats, including serum, gut, …

    20255 citations
  • Migraine headaches: opportunities for management with precision nutrition

    BI Brown - Nutritional Med J, 2022 - nmi.health

    … 5-HTP (5 mg per kg of body weight daily) when compared with placebo.However, it should be noted that both 5-HTP … by an unrestricted donation from Pure Encapsulations, Sudbury, MA…

    20224 citations
  • Flavonoids improve neurotransmitters for Parkinson's treatment: mechanism and therapeutic potential

    Y Zhang, Y Bu, M Song, Z Hao, J Chen - Frontiers in Pharmacology, 2026 - frontiersin.org

    Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder worldwide, and it stands out as one of the neurological conditions exhibiting the …

    2026

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-07-18. DSLD Label ID: 295132. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.