SAMe 400 mg®
Non-Nutrient / Non-BotanicalBrand: Protocol For Life Balance
Net Contents
60 Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 07359 10141 8
Product Version
CODE P0141D V4
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Tablet(s) · 2–4 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAMe(S-Adenosyl-L-Methionine Disulfate Tosylate) | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested usage: Take 1 tablet 2 to 4 times daily, or as directed by your healthcare practitioner.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Cautions/Interactions: Theoretically, SAMe could increase the effects and adverse effects of products that increase serotonin levels, including 5-hydroxytryptophan (5- HTP), Hawaiian baby woodrose, L-tryptophan, and St. John's wort. In addition, SAMe may interact with MAO inhibitors, L-Dopa, antidepressants and other serotonergic drugs. Consult healthcare practitioner if pregnant/nursing, taking medication, or have a medical condition, especially bipolar or anxiety disorders.
Precautions re: Allergies
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Storage
Storage
Refrigeration recommended after opening.
Formulation
Formula re: Contains
How it works: SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient normal aches and pains resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the maintenance of a positive mood.
Formulation re: Other
Natural color variation may occur in this product.
Formulation re: Other
Supports nervous system and joint health
Formula re: Contains
Stabilized SAMe, smaller tablet
Formulation re: Does NOT Contain
No enteric coating needed
Formulation re: Does NOT Contain
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients.
FDA Statements
FDA Statement of Identity
A Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Manufacturer & Distributor
Manufacturer
Protocol For Life Balance
395 S. Glen Ellyn Rd., Bloomingdale, IL, 60108, USA
Market Reference
Protocol For Life Balance SAMe 400mg 60 Tablets
iHerb4.9(35)$75.00
Protocol For Life Balance E-400 Softgels
iHerb4.9(55)$37.00
Spring Valley SAMe
Walmart4.6(186)$24.96
Nature Made SAM-e Complete 400 mg
Walgreens.com4.6(190)$54.99
BrainMD SAMe Mood & Movement 400 30 Tablets
Blue Sky Vitamin4.4(121)$59.99
Nutralife The Original SAMe 400 mg Enteric Coated Tablets
Swanson Health Products5.0(7)$30.69
Protocol For Life Balance Coq10 600 mg Softgels
Pine Street Clinic4.8(46)$65.00
SAMe 400 mg
Nutriessential.com4.7(417)$64.79
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
GNC
3.7 (38)Vitamin & supplements store
1004B Lititz Pike, Lititz, PA 17543
SAVEMART
4.5 (322)Health food store
241 W Roseville Rd #6, Lancaster, PA 17601
Akron Nutrition Center
4.5 (120)Health food store
22 N 7th St, Akron, PA 17501
The Vitamin Shoppe
4.7 (97)Vitamin & supplements store
415 Loucks Rd, York, PA 17404
GNC
4.5 (32)Vitamin & supplements store
564 Centerville Rd, Lancaster, PA 17601
The Vitamin Shoppe
4.5 (127)Vitamin & supplements store
5125 Jonestown Rd Unit no. 145, Harrisburg, PA 17112
GNC
4.1 (18)Vitamin & supplements store
2600 Willow Street Pike N, Willow Street, PA 17584
The Vitamin Shoppe
4.4 (198)Vitamin & supplements store
2719 N Meridian Blvd, Broadcasting Square Dr Suite W 3, Reading, PA 19610
Research & Studies
MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial
Heart Protection Study Collaborative Group - The Lancet, 2002 - Elsevier
… , or diabetes were randomly allocated to receive antioxidant vitamin supplementation (600 mg vitamin E, 250 mg vitamin C, and 20 mg β-carotene daily) or matching placebo. Intention-…
20021,648 citationsSixteen weeks of supplementation with a nutritional quantity of a diversity of polyphenols from foodstuff extracts improves the health-related quality of life of …
C Romain, LH Chung, E Marín-Cascales… - Nutrients, 2021 - mdpi.com
… Hence, chronic supplementation with nutritional diversity and dosing of a Mediterranean diet… mental health, concomitant with the improvement of body composition, in healthy subjects …
202126 citationsTwo-month period of 500 mg lecithin-based delivery form of quercetin daily dietary supplementation counterbalances chronic fatigue symptoms: A double …
M Rondanelli, A Riva, G Petrangolini, C Gasparri… - Biomedicine & …, 2023 - Elsevier
… Given this background, the aim of this study was to evaluate if a 2-month period of daily Quercetin Phytosome™ 500 mg supplementation is of benefit for the relief of CF. …
202312 citationsAmerican Association of Clinical Endocrinologists Medical Guidelines For Clinical Practice For The Prevention and Treatment of Postmenopausal Osteoporosis: 2001 …
SF Hodgson, NB Watts, JP Bilezikian… - Endocrine …, 2003 - endocrinepractice.org
… are obtained when the same instrument and, ideally, the same technologist are used. … Calcium (500 to 1,000 mg/day) and vitamin D (400 to 800 IU/day) supplementation can reduce the …
2003509 citationsEffect of targeted nutrient supplementation on physical activity and health-related quality of life in COPD: study protocol for the randomised controlled NUTRECOVER …
RJ Beijers, LEJ van Iersel, LT Schuurman… - BMJ open, 2022 - bmjopen.bmj.com
… A block randomisation will be conducted to ensure equal allocation of patients in the … The independent researcher will use the minimisation method to maintain an equal distribution in …
202214 citationsInvitation to Holistic Health: A Guide to Living a Balanced Life:.
C Eliopoulos - 2009 - books.google.com
… healthcare consumer. This new edition of Invitation to Holistic Health provides the same … tional supplementation. The results continue to demonstrate that the foods we eat determine …
200947 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-04-24. DSLD Label ID: 326476. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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