HMB

Suggested Use

DIRECTIONS: For adults; take four (4)capsules three times daily; preferably with ameal. Do not exceed recommended dose.

• 

  Optimum Nutrition HMB 1000 Caps 90 Capsules

  Optimum Nutrition - US4.5(508)

  $43.99
• 

  Beyond Raw Chemistry Labs HMB Powder

  GNC4.4(32)

  $39.99
• 

  Gorilla Mind HMB Supplement

  Gorilla Mind4.8(98)

  $22.21
• 

  HMB+ Build Lean Muscle

  Inno Supps4.8(1000)

  $22.38
• 

  Nutricost HMB

  Nutricost4.6(1600)

  $12.97
• 

  Hmb

  Hi-Tech Pharmaceuticals

  $29.95
• 

  BodyTech HMB + 120 Vegetable Capsules

  The Vitamin Shoppe3.9(16)

  $29.99
• 

  Now Foods Double Strength HMB 1,000 mg 90 Tablets

  Muscle & Strength4.7(454)

  $28.99

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• The Vitamin Shoppe

  4.6 (187)

  Vitamin & supplements store

  3120 Peoples St, Johnson City, TN 37604

  Directions(423) 282-2507

• GNC

  4.4 (41)

  Vitamin & supplements store

  2101 Fort Henry Dr, Kingsport, TN 37664

  Directions(423) 246-1916

• De novo biosynthesis of 3-hydroxy-3-methylbutyrate as anti-catabolic supplement by metabolically engineered Escherichia coli

  SJ Huang, MJ Lai, AY Chen, EI Lan - Metabolic Engineering, 2024 - Elsevier

  … novo HMB biosynthetic pathway that enables HMB production from renewable resources. This novel HMB … iso-fatty acid pathway for converting acetyl-CoA to HMB-CoA. Subsequently, …

  20246 citations

• Oral nutritional supplement with β-hydroxy-β-methylbutyrate (HMB) improves nutrition, physical performance and ameliorates intramuscular adiposity in pre …

  LN Peng, YC Cheng, PC Yu, WJ Lee, MH Lin… - … of nutrition, health and …, 2021 - Elsevier

  … -β-methylbutyrate (HP-HMB) has been shown to improve … roles of HP-HMB supplementation on the intramuscular adiposity … -HMB supplementation on muscle and metabolic health for …

  202170 citations

• Hepatic SNHG9 links gut microbiota to liver protection in drug-induced liver injury

  W Bao, B Hang, D Zeng, J Mao, LB Pan… - Nature …, 2026 - nature.com

  … Supplementation with HMB or HMB-producing microbes robustly induces hepatic SNHG9 … of serum HMB concentration with fecal Lactobacillus abundance in healthy individuals. …

  2026

• A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

  S Jalili-Firoozinezhad, FS Gazzaniga… - … biomedical engineering, 2019 - nature.com

  … types of culture medium with the healthy human microbiome (Hmb) stock in standard culture … ribosomal RNA sequencing after 3 d of culture (Supplementary Fig. 7a). Samples of these …

  2019932 citations

• Effects of leucine and its metabolite β‐hydroxy‐β‐methylbutyrate on human skeletal muscle protein metabolism

  DJ Wilkinson, T Hossain, DS Hill… - The Journal of …, 2013 - Wiley Online Library

  … of HMB on human muscle protein turnover and compare this with Leu. Our hypotheses were: (i) HMB provision would acutely stimulate MPS (ii) HMB … of HMB in free-acid form (FA-HMB), …

  2013691 citations

• Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates DSS-induced colitis by inhibiting ERK/NF-κB activation in macrophages

  J Liu, D Niu, Y Tang, R Zheng, Y Qin, X Cheng, S Pan… - Phytomedicine, 2025 - Elsevier

  … effects of HMB treatment on … HMB treatment substantially mitigated colonic damage in murine models of DSS-induced colitis, highlighting its anti-inflammatory potential. Notably, HMB …

  202513 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2011-11-25. DSLD Label ID: 1743. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.