SAM-e S-Adenosylmethionine 200 mg®
Non-Nutrient / Non-BotanicalBrand: PhysioLogics
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
2 Tablet(s)
Servings Per Container
15
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 16963 07116 1
Product Version
PROD. NO. 7116 B36221 04D
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 2 Tablet(s) · 3 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosylmethionine | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: For adults, we recommend taking two (2) tablets three times daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal or follow the advice of your health care professional.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Precautions re: All Other
Discontinue use and consult your doctor if any adverse reactions occur.
Precautions re: All Other
TAMPER RESISTANT: Do not use if blister seal is cut, torn or open.
Precautions re: Children
KEEP OUT OF REACH OF CHILDREN.
Storage
Storage
Store at room temperature and avoid excessive heat.
Formulation
Formulation re: Does NOT Contain
FREE OF: artificial flavor, preservatives, sugar, milk, lactose, soy, gluten, wheat, yeast, fish.
FDA Statements
FDA Disclaimer Statement
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
Supports Mood and Emotional Well-being
Brand IP Statement(s) re: (c), (TM), (SM)
(C)PhysioLogics, 2011
General Statements: All Other Content
A NOTE ABOUT OUR ENTERIC COATING: The enteric coating helps the breakdown of SAM-e occur in the small intestine.* In addition, the enteric coating is designed to protect SAM-e from moisture and serve as a protective barrier so that SAM-e can be absorbed where it can provide you with its benefits.*
General Statements: All Other Content
Part No. 22-71165
General Statements: All Other Content
PRODUCT BENEFITS: SAM-e is involved in over 35 biochemical reactions involving enzymatic transmethylation.* The methylation process is the mechanism by which the body rids itself of potentially damaging compounds, synthesizes neurotransmitters, regulates enzyme activity within the cell and maintains the flexibility of cell membranes.* Sam-e supports mood and emotional well-being.*
General Statements: All Other Content
Laboratory Tested to Guarantee Quality
General Statements: All Other Content
For Health Care Professional Use Only
General: Product/Version Code
PROD. NO. 7116 B36221 04D
General Statements: All Other Content
As a reminder, discuss the supplements and medications you take with your health care providers.
Manufacturer & Distributor
Other
Other
1-800-765-6775
Manufacturer
PhysioLogics, LLC
2100 Smithtown Avenue, Ronkonkoma, NY, 11779, U.S.A.
Market Reference
Pure Encapsulations SAMe 60 Capsules
Pure For You4.4(70)$84.50NOW Foods SAMe 200 mg 60 Capsules
Walmart - DailyVita4.7(447)$23.41Jarrow Formulas SAM-e 200 mg Tablets
iHerb4.6(444)$18.34Doctor's Best SAM-e 200 mg Enteric Coated Tablets
Target4.7(665)$36.99SuperSmart SAM-e 200mg
supersmart.com4.6(65)$50.23Protocol For Life Balance SAMe 200 mg 60 Capsules
Walmart - Pattern4.9(75)$40.00Source Naturals SAMe 200 mg Tablets
Vitacost.com4.7(136)$46.89NOW Foods SAMe 200 mg 60 Veg Capsules
NOW$74.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Research & Studies
S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… depressive symptoms were seen ranging from 200 mg to 3200 mg. Many studies started at … doses starting at 200 mg to 800 mg for mild–moderate depression and 800 mg daily in one to …
202410 citationsSafety and efficacy of S-adenosylmethionine (SAMe) for osteoarthritis
KL Soeken, WL Lee, RB Bausell, M Agelli… - J Fam Pract, 2002 - cdn.mdedge.com
… ring sulphur-containing physiologic compound synthesized … as a dietary supplement to promote joint health, mobility, and … ,” “Sammy,” and “SAM-e.” Results were then combined into the …
2002175 citationsS-adenosylmethionine (SAMe) as treatment for depression: a systematic review
A Williams, C Girard, D Jui, A Sabina… - Clinical and …, 2005 - search.proquest.com
… used to pair more than 200 medical conditions with CAM … 200 mg oral SAMe twice daily and increased to 1600 mg by … received 200 mg oral SAMe twice daily and increased to 1600 mg …
2005146 citationsS-adenosylmethionine
T Bottiglieri, PL Gerbarg, RP Brown - … and Integrative Treatments …, 2017 - books.google.com
… biochemistry at the National Institute of Mental Health. An amino acid–derived metabolite… mg/day as tolerated. Elderly, debilitated, or medication-sensitive patients should start at 200 mg…
20179 citationsComplementary and Alternative Medicine in Pharmacology
L Dehner - Pharmacology for Rehabilitation Professionals-E …, 2010 - books.google.com
… (CS), and S-adenosylmethionine (SAM-e) for the pain and … liver, has varied physiologic functions, including stimulation … 1.2 g (600 mg 2 day) of SAM-e or 200 mg (100 mg 2 day) of …
2010S-Adenosyl-L-methionine for major depressive disorder
D De Berardis, L Orsolini, F Iasevoli… - Melatonin …, 2016 - Springer
… SAMe is an important physiologic compound, widely distributed throughout the body tissues and … The dose range is typically 100–200 mg/day (or 200–400 mg/day) IM or 800–1,200 mg/…
20163 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-01-24. DSLD Label ID: 29146. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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