Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
Not specified
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 16963 50260 3
Product Version
Not specified
Suggested Use
Directions: For adults; take one (1) tablet three times daily; preferably on an empty stomach. In order to obtain maximum benefits; SAM-e should be taken at least 30 minutes prior to a meal or follow the advice of your health care professional.
Market Reference
Nature Made SAM-e Complete 400 mg
CVS Pharmacy4.6(190)$64.99(3 pack) Spring Valley SAMe Dietary Supplement Value Pack, 400 mg, 40 Count
Walmart4.6(186)$74.88Walgreens Sam-e 400 mg Coated Caplets
Walgreens.com$49.99Jarrow Formulas SAM-e 400 60 Tablets
Life Extension4.7(430)$38.99Doctor's Best SAMe 400 mg Double Strength Enteric Coated Tablets
Target4.7(771)$52.99BrainMD SAMe Mood & Movement 400 30 Tablets
BrainMD by Dr Amen4.4(121)$44.962 Pack-sam-e 400 Mg Vegan, Kosher, Non-gmo, Soy-, Gluten-,
eBay4.3(32)$73.55Swanson 400 mg SAMe 30 Tablets
Swanson Health Products4.6(394)$25.69
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.4 (119)Vitamin & supplements store
2021 Gunbarrel Rd, Chattanooga, TN 37421
GNC
3.2 (42)Vitamin & supplements store
2100 Hamilton Pl Blvd #252, Chattanooga, TN 37421
Nature's Finest Nutrition
4.7 (85)Vitamin & supplements store
7232 Lee Hwy, Chattanooga, TN 37421
Nutrition World
5.0 (1737)Health food store
6201 Lee Hwy, Chattanooga, TN 37421
STACK'd Supplements
5.0 (133)Vitamin & supplements store
5724 TN-153 b, Hixson, TN 37343
Nutrition Shoppe
5.0 (18)Vitamin & supplements store
112 Herron St, Fort Oglethorpe, GA 30742
NutritionFaktory.com
4.5 (39)Vitamin & supplements store
6053 Artesian Cir, Ooltewah, TN 37363
The Vitamin Shoppe
4.7 (80)Vitamin & supplements store
5546 TN-153 #114, Hixson, TN 37343
Research & Studies
S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… 400 mg once or twice daily, 400 mg daily titrated to 800 mg twice daily for ADHD, and 400 mg daily titrated to 800 mg … For depression, SAMe was dosed between 200 and 3200 mg daily, …
202410 citations… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… MSI discovered that formulations of SAM-e including propyl gallate have enhanced … has a dosage strength of 400 mg (based on the weight of the free base). The SAM-e counter-ions are …
202014 citationsSafety and efficacy of S-adenosylmethionine (SAMe) for osteoarthritis
KL Soeken, WL Lee, RB Bausell, M Agelli… - J Fam Pract, 2002 - cdn.mdedge.com
… ring sulphur-containing physiologic compound synthesized … as a dietary supplement to promote joint health, mobility, and … ,” “Sammy,” and “SAM-e.” Results were then combined into the …
2002174 citationsA comprehensive review on the efficacy of S-Adenosyl-L-methionine in Major Depressive Disorder.
D De Berardis, L Orsolini, N Serroni… - CNS & Neurological …, 2016 - ingentaconnect.com
… Data Synthesis: SAMe is an important physiologic compound, … after supplementation of 800-1600 mg/d of oral SAMe. … Sadenosylmethionine (SAM-e) for the treatment of depression in …
201695 citationsRapid review of breast cancer treatment side effects and dietary supplement/integrative options from A to Z: what helps, harms, or does nothing?
MA Moyad - Integrative Medicine for Breast Cancer: An Evidence …, 2016 - Springer
… physiologic locations where it can help to ameliorate pain. … SAM-e in my experience is prohibitive cost because SAM-e … sexual health should also be investigated from SAM-e depression …
20166 citationsEvidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
GI Papakostas - Journal of Clinical Psychiatry, 2009 - psychiatrist.com
… increasingly interested in nonpharmaceutical supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-l-methionine (SAM-e), a naturally …
2009178 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-01-24. DSLD Label ID: 29147. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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