Homocysteine Formula B-6 B-12 And Folic Acid®

Other Combinations

Brand: PhysioLogics

CapsuleOther CombinationsOff Market
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Net Contents

60 Vegetarian Capsules

Serving Size

2 Capsule(s)

Servings Per Container

30

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 16963 12045 6

Product Version

PROD. NO. 12045 B78119 03D

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

5Active Ingredients

5 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3% Daily Value Coverage

3 ingredients report a %DV; 3 meet or exceed 100% DV.

1Dietary Attributes

Label states: Vegetarian.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 2 Capsule(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Vitamin B6(Pyridoxine Hydrochloride)50 mg2500%
Folic Acid400 mcg100%
Vitamin B12(Cyanocobalamin)500 mcg8333%
Trimethylglycine1000 mg
Pyridoxal 5-Phosphate6 mg

Not Present

Other Ingredients

HypromelloseStearic AcidMannitolCelluloseVegetable Magnesium StearateDicalcium PhosphatePhytO2X Blend

Target Groups

VegetarianAdult (18 - 50 Years)

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, preferably with a meal, or follow the advice of your health care professional. As a reminder, discuss the supplements and medications you takewith your health care providers.

Warnings & Precautions

Precautions re: Children

KEEP OUT OF REACH OF CHILDREN.

Precautions re: Pregnant or Nursing or Prescription Medications

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Precautions re: All Other

Discontinue use and consult your doctor if any adverse reactions occur.

Precautions re: All Other

For Health Care Professional Use Only

Precautions re: All Other

TAMPER RESISTANT: Do not use if seal under cap is broken or missing.

Storage

Storage

Store at room temperature and avoid excessive heat.

Formulation

Formulation re: Does NOT Contain

FREE OF: artificial color, artificial flavor, preservatives, sugar, milk, lactose, soy, gluten, wheat, yeast, fish, sodium.

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

General Statements: All Other Content

Laboratory Tested to Guarantee Quality

General Statements: All Other Content

NEW FORMULATION

General: Product/Version Code

PROD. NO. 12045 B78119 03D

General Statements: All Other Content

PRODUCT BENEFITS: Homocysteine Formula is a unique combination of select high potency B-vitamins to help promote heart health by assisting in homocysteine metabolism in the body.* Vitamin B-6, B-12 and Folic acid are a part of the single carbon cycle which results in the formation of the amino acid methionine. This reaction helps to maintain homocysteine levels already within the normal range.* Healthy levels of homocysteine are important for heart and circulatory health.*

General Statements: All Other Content

Promotes Cardiovascular Health*

Brand IP Statement(s) re: (c), (TM), (SM)

©PhysioLogics, 2011

Brand IP Statement(s) re: (c), (TM), (SM)

PhytO2X(R) is a special blend of antioxidants, the purpose of which is to maintain the freshness of the ingredients.

Seals/Symbols

DOCTOR RECOMMENDED

Manufacturer & Distributor

Manufacturer

PhysioLogics, LLC

One Nutrition Plaza, Carbondale, IL, 62901, U.S.A.

Other

Other

1-800-765-6775

Market Reference

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Research & Studies

  • Folic acid supplementation in patients with elevated homocysteine levels

    AD Kaye, GM Jeha, AD Pham, MC Fuller, ZI Lerner… - Advances in …, 2020 - Springer

    … caused by a nutritional deficiency of folate, vitamin B 12 , or vitamin B 6 in the setting of genetic … from vitamin B 6 deficiency following isoniazid therapy. Folate and B 12 deficiencies are …

    2020195 citations
  • Impact of supplementation with vitamins B6, B12, and/or folic acid on the reduction of homocysteine levels in patients with mild cognitive impairment: A systematic …

    G Olaso‐Gonzalez, M Inzitari, G Bellelli, A Morandi… - IUBMB …, 2022 - Wiley Online Library

    … levels of vitamins B 12 , B 6 , and folate. Previous … homocysteine levels. This review aimed to assess the effects of treatment with vitamins B 6, B 12 , and/or folic acid in the homocysteine …

    202253 citations
  • Effect of physiological doses of oral vitamin B12 on plasma homocysteine: a randomized, placebo-controlled, double-blind trial in India

    US Deshmukh, CV Joglekar, HG Lubree… - European journal of …, 2010 - nature.com

    … doses of B 12 and folic acid on plasma total homocysteine (… ) reduced circulating total homocysteine (tHcy) concentrations. … trial of B 12 supplementation on plasma homocysteine, using …

    2010103 citations
  • Biomarkers of Nutrition for Development (BOND): vitamin B-12 review

    LH Allen, JW Miller, L De Groot… - The Journal of …, 2018 - academic.oup.com

    … Cobalamins are absorbed by an active physiologic process … S-adenosylhomocysteine and homocysteine can serve as … that included folic acid and vitamin B-6 as well as cobalamin (81). …

    2018419 citations
  • Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning

    N de Jong, MJMCA Paw, LC de Groot… - … American journal of …, 2001 - academic.oup.com

    … The influence of oral multimicronutrients in physiologic … B-12), folate, and pyridoxal 5-phosphate (PLP, or vitamin B-6) … pharmacologic doses of folic acid, vitamin B-12, vitamin B-6, or all …

    200195 citations
  • Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete

    MC McKinley, H McNulty, J McPartlin, JJ Strain… - The American journal of …, 2001 - Elsevier

    … Current data suggest that physiologic doses of vitamin B-6 have no significant … B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both. …

    2001166 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2011-12-23. DSLD Label ID: 3451. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.