The Original SAMe 400 mg™
Non-Nutrient / Non-BotanicalBrand: NutraLife
Functions
Net Contents
60 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
Not specified
Product Version
Not Present
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian, Gluten-Free, Kosher.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Egg
- Fish
- Shellfish
- Tree Nuts
- Wheat
- Soy
- Gluten
Free From
- Peanut
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl-Methionine | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Use: Clinical studies show that supplementation of 400 mg (or one tablet) a day is effective for most people. Different levels of supplementation may be beneficial to some people. Please refer to our package insert for more information.
Warnings & Precautions
Precautions re: All Other
Caution: Do not use if blister foil is punctured or appears in any way to have been tampered with.
Precautions re: Children
Keep out of reach of children.
Precautions re: Pregnant or Nursing or Prescription Medications
If you are currently taking prescription anti-depressants, consult your physician before using SAMe. If you are pregnant or lactating, consult your physician before taking this product.
Precautions re: All Other
If you suffer from bipolar (manic) depression, do not use this product.
Precautions re: Pregnant or Nursing or Prescription Medications
If you are pregnant or lactating, consult your physician before taking this product.
Precautions re: All Other
NutraLife SAMe tablets are sealed in blister packs to ensure product safety, quality and freshness.
Storage
Storage
This product should be stored in a dry, cool place.
Formulation
Formula re: Contains
400 mg active S-Adenosyl-Methionine per tablet
Formulation re: Other
Manufactured in Accordance with GMP
Formulation re: Other
Clinically shown to maintain: Mood & emotional well being Healthy liver function Joint health and comfort Joint mobility
Formulation re: Other
SAMe is found in every living being. It is an important physiological agent synthesized by the body, and it is involved in over 40 biochemical reactions, some of which effect: MOOD SAMe and Emotional Well-Being: SAMe is essential to the manufacture of many important brain compounds such as neurotransmitters and phospholipids, which are critical for maintaining healthy mood and emotional well-being. JOINTS SAMe and Joint Mobility: Clinical Studies indicate that SAMe may play an important role in the manufacture of cartilage and that SAMe helps produce proteoglycans, essential components in healthy joint function and mobility. LIVER SAMe and Liver Function: SAMe is involved in many processes of the liver. SAMe is essential to maintaining glutathione levels, which is critical for proper liver function. As people age, SAMe levels can decrease. SAMe supplementation may be an important factor in maintaining mobility, and a healthy body and mind. NutraLife SAMe: NutraLife SAMe is the same form that has been available in Europe for over two decades. NutraLife offers the only form of SAMe with 20 years of historical data for both effectiveness and safety. NutraLife SAMe is manufactured and packaged with the highest quality and safety standards.
Formula re: Contains
Each NutraLife SAMe tablet contains 400 mg of active S-Adenosl-methionine and is manufactured in full accordance with GMP.
Formulation re: Other
Nutralife SAMe is the original SAMe brand introduced to the United States almost a decade ago. Nutralife SAMe continues to be made with the highest quality active S, S isomer SAMe raw material.
Formula re: Kosher
Nutralife SAMe is kosher certified by Star-K and contains NO animal byproducts.
Formulation re: Does NOT Contain
Nutralife SAMe does not contain Talc.
Formulation re: Other
Nutralife SAMe tablets are manufactured in a carefully controlled environment and are cold from blister packed to ensure a more than two year stability rating.
Formula re: Kosher
NutraLife SAMe enteric coated tablets are Kosher certified by: Star-K (Kosher)
Formulation re: Does NOT Contain
This product contains no peanuts, eggs, dairy, soy, wheat, yeast, gluten, tree nuts, crustacean shellfish, fish or other animal byproducts.
Formula re: Contains
Each NutraLife SAMe tablet contains 800 mg SAMe tosylate disfulate, which includes 400 mg of the active ingredient SAMe (S-Adenosyl-Methionine).
FDA Statements
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the food and drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
NutraLife Health Products Incorporated
General Statements: All Other Content
Value size!
Seals/Symbols
Star-K (Kosher)
Manufacturer & Distributor
Distributor
NutraLife Health Products Inc.
Lakewood, NJ, 08701, U.S.A.
1-877-688-7254
Market Reference
NutraLife SAMe, 200 mg, 60 Enteric Coated Tablets
iHerb4.8(645)$19.75Nature Made SAM-e Complete 400 mg
Walmart4.5(310)$53.98Spring Valley SAMe Enteric Coated Caplets
Walmart4.6(188)$24.96Nutra-Life Magnesium Complete Forte 250 caps
Netpharmacy4.8(120)$9.51LowestSAMe 400 mg - 60 Tablets
Collaborative Natural Health Partners$69.95Magnesium Complete 400 120 Caps
Netpharmacy4.9(10)$12.68SAMe 400 mg - 60 tabs
Nutriessential.com$64.79Protocol For Life Balance SAMe 400mg 60 Tablets
boulevardcompounding.com4.9(36)$73.99
Where to Buy Locally
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4.5 (503)Vitamin & supplements store
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7449 S Lindbergh Blvd, St. Louis, MO 63125
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Research & Studies
Efficacy of the Dietary Supplement S-Adenosyl-L-Methionine
CW Fetrow, JR Avila - Annals of Pharmacotherapy, 2001 - journals.sagepub.com
… First described in 1953 by Cantoni,3 SAMe is naturally … received 800 mg/d of oral SAMe (400 mg at 0800 and 400 mg at … supplement in the US under the Dietary Supplement Health …
200163 citationsL-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis
AM Mahdavi, R Mahdavi, S Kolahi, M Zemestani… - Nutrition Research, 2015 - Elsevier
Considering the pathologic importance of oxidative stress and altered lipid metabolism in osteoarthritis (OA), this study aimed to investigate the effect of l-carnitine supplementation on …
201551 citationsNovel multi-ingredient supplement facilitates weight loss and improves body composition in overweight and obese individuals: a randomized, double-blind …
JP Nederveen, AJ Mastrolonardo, D Xhuti, A Di Carlo… - Nutrients, 2023 - mdpi.com
… designed to facilitate mitochondrial function and metabolic health … Those who qualified upon initial screening were invited to … hospital gown with the same undergarments for every visit. …
202340 citationsSixteen weeks of supplementation with a nutritional quantity of a diversity of polyphenols from foodstuff extracts improves the health-related quality of life of …
C Romain, LH Chung, E Marín-Cascales… - Nutrients, 2021 - mdpi.com
… Hence, chronic supplementation with nutritional diversity and dosing of a Mediterranean diet… mental health, concomitant with the improvement of body composition, in healthy subjects …
202128 citationsLower RXRA and TFRC expression despite higher mineral and vitamin intake in diabetic pregnant women with pregnancy-specific urinary incontinence
SMB Costa, RLS Hallur, MN Fioretto… - Clinical Nutrition Open …, 2025 - Elsevier
… challenge to global health and 35 medical resource[2,3]. … quantified using a nutritional software (Nutrilife version 9.12). … value greater than or equal to the one found; mg: milligram; ug: …
20252 citationsHypoglycemic effects of antioxidant-rich plant extracts on postprandial glycemic responses in participants with prediabetes (GLARE study)
WXJ Lim, CS Gammon, PR von Hurst… - … Foods in Health and …, 2021 - ffhdj.com
… or coffee formulations, no health supplements 24 hours to visit, … subgroups, p<0.05 using the student t-test assuming equal … To the best of our knowledge the present study is the first to …
202110 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-09-25. DSLD Label ID: 293168. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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