Methyl Folate Optimizer®
Botanicals with NutrientsBrand: NuMedica
Net Contents
60 Vegetable Capsule(s)
Serving Size
2 Capsule(s)
Servings Per Container
30
Supplement Form
Capsule
Bar Code (UPC/SKU)
8 12527 01011 6
Product Version
Not Present
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
6 distinct active ingredients are disclosed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
4 ingredients report a %DV; 4 meet or exceed 100% DV.
Label states: Vegetarian, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Wheat
- Soy
Free From
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 2 Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Folate | 8 mg | 2000% |
| 6S-5-Methyltetrahydrofolic Acid, Glucosamine Salt | 5 mg | — |
| Folinic Acid | 3 mg | — |
| Vitamin B3(Niacinamide) | 150 mg | 750% |
| Vitamin B-6(Pyridoxal 5-Phosphate) | 25 mg | 1250% |
| Vitamin B12(Methylcobalamin) | 1000 mcg | 16667% |
| AstraGin(Astragalus root extract, Panax notoginseng root extract) | 12.5 mg | — |
| BioPerine | 2 mg | — |
Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: Take two capsules daily or as directed by your healthcare practitioner.
Warnings & Precautions
Precautions re: Children
Caution: Keep out of reach of children.
Precautions re: All Other
Professional use only
Storage
Storage
Storage: Keep tightly closed in a cool, dry place.
Formulation
Formula re: Contains
The 5-MTHF in this formula, Quatrefolic, is the most biologically active form of folate, allowing rapid uptake into the bloodstream. Vitamin B-12 is also provided in its active form, methylcobalamin, to further support methylation and healthy homocysteine levels. NuMedica has included its advanced absorption technology - a proprietary blend of AstraGin and BioPerine.
Formulation re: Does NOT Contain
Contains no: Wheat, corn protein, yeast, soy, animal or dairy products, artificial colors, sweeteners or preservatives.
Formula re: Contains
With AstraGin and BioPerine for optimal absorption
Formulation re: Does NOT Contain
Gluten free
Formula re: Contains
Quatrefolic 5-MTHF Active Folate
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
Methyl-Folate Optimizer is a comprehensive formula designed to support optimal methylation and homocysteine levels.
General Statements: All Other Content
Clinical studies have shown the components of this proprietary blend to increase folate absorption by up to 50.4%.
General Statements: All Other Content
This formula meets or exceeds cGMP quality standards.
General Statements: All Other Content
Achieving physiological balance Advanced methylation support
General Statements: All Other Content
Gold medallion formula
Seals/Symbols
Gluten free
Brand IP Statement(s) re: (c), (TM), (SM)
Quatrefolic is trademarked by Gnosis S.p.A. Patent No. 7,947,662. BioPerine is a registered trademark of Sabinsa Corp. AstraGin is a registered trademark of NuLiv Science.
General Statements: All Other Content
Rapid uptake 5-MTHF Bioactive folate B Activated B-Vitamins
Seals/Symbols
Vegetable capsules
Manufacturer & Distributor
Manufacturer
NuMedica
9503 E. 55th Place, Tulsa, OK, 74145
800.869.8100
Market Reference
NuMedica Methyl Folate Optimizer
SupplementRelief.com4.9(9)$44.95NuMedica Methyl Folate 5-MTHF 120 Capsules
SupplementRelief.com4.6(7)$25.90NuMedica Methyl Folate HP 60 Capsules
SupplementRelief.com5.0(1)$55.95NuMedica Methyl-Plex B 60 Capsules
Cincinnati Health Institute4.9(15)$33.90NuMedica Liposomal Methylsorb
TheNatural.com5.0(3)$55.95Nutri Methyl Folate 15mg 120 Vegan Tablets
Nature's Fusions Essential Oils4.7(48)$29.99NuMedica Mitospark
SupplementRelief.com4.0(1)$69.95NB Pure Methyl Folate Spray
NB Pure4.9(295)$17.95
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.5 (134)Vitamin & supplements store
9390 6 Mile Cypress Pkwy #5, Fort Myers, FL 33966
Fort Myers Nutrition
5.0 (356)Wellness center
4901 Palm Beach Blvd #380, Fort Myers, FL 33905
THE B-12 STORE, Fort Myers
4.8 (209)Vitamin & supplements store
4125 Cleveland Ave #1660, Fort Myers, FL 33901
“Nutriendo Vidas” Fort Myers FL. Empresario Independiente Omnilife/Seytu .
4.7 (6)Sports nutrition store
373 Muskegon Ave, Fort Myers, FL 33905
GNC
4.2 (46)Vitamin & supplements store
3398 Forum Blvd Unit 114, Fort Myers, FL 33905
Total Nutrition
4.9 (108)Vitamin & supplements store
2311 Santa Barbara Blvd S #104, Cape Coral, FL 33991
The Vitamin Shoppe
4.4 (154)Vitamin & supplements store
11741 S Cleveland Ave #10, Fort Myers, FL 33907
Total Nutrition
4.7 (22)Vitamin & supplements store
9918 Gulf Coast Main St #145, Fort Myers, FL 33913
Research & Studies
Optimization of dietary folate or low-dose folic acid supplements lower homocysteine but do not enhance endothelial function in healthy adults, irrespective of the …
CH Pullin, PAL Ashfield-Watt, ML Burr, ZE Clark… - Journal of the American …, 2001 - jacc.org
… This study demonstrates that in healthy individuals, optimization of dietary folate intake or supplementation with low-dose folic acid lowers plasma homocysteine but does not enhance …
200184 citationsThe evolution of folate supplementation–from one size for all to personalized, precision, poly-paths
Q He, J Li - Journal of Translational Internal Medicine, 2023 - degruyterbrill.com
… The most used folate supplement is folic acid, a synthetic oxidative form, and folic acid grain fortification is a success story of public health. However, the metabolic conversion of …
202348 citations… of an optimized HPLC-UV analytical method for the quantification of 5-Methyltetrahydrofolate (Active Folate) in dietary Supplements: Application to commercial tablets …
A Alshishani, M Shalash, A Aldalaty, L Shaghlil - Microchemical Journal, 2024 - Elsevier
… supplements, thereby safeguarding consumer health. Future regulatory policies should mandate stability testing and accurate labeling to enhance the reliability of dietary supplement. …
20243 citationsOriginal Internist
BTAREV DANGEROUS - 2009 - prohealthseminars.com
… Health care is by definition to care for health, and not to be disregardent of it. … really need of our health care is in its provision, not in its payment. The answers to most health loss and the …
2009
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2018-08-31. DSLD Label ID: 180180. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
Related Products

100% Daily Value Multi-Vitamin
Superior Source

100% Greens+Whey Chocolate
BioChem

100% Greens+Whey Chocolate
BioChem

100% Greens+Whey Vanilla
BioChem