Brand: NOW

Tablet or PillNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

60 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 33739 00141 2

Product Version

CODE 0141 V3

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

2Active Ingredients

2 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3Dietary Attributes

Label states: Vegan, Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Egg
  • Shellfish
  • Wheat
  • Soy
  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Tablet(s) · 1 per day

IngredientAmount Per Serving
SAMe400 mg
from 800 mg of S-Adenosyl-L-Methionine Disulfate Tosylate800 mg

Not Present

Other Ingredients

CelluloseCroscarmellose SodiumMethacrylic AcidMagnesium StearateSilicaTriethyl CitrateStearic AcidCitric AcidAscorbic Acid

Target Groups

VeganVegetarianAdult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 1 tablet daily, preferably on an empty stomach.

Warnings & Precautions

Precautions re: All Other

Warning: Individuals with bipolar (manic) depression should not take SAMe unless under professional medical supervision.

Precautions re: All Other

Do Not Eat Freshness Packet. Keep in Bottle.

Storage

Storage

Refrigeration recommended after opening.

Formulation

Formulation re: Vegetarian/Vegan

Vegetarian Formula

Formulation re: Does NOT Contain

Contains no sugar, salt, starch, yeast, wheat, gluten, soy, milk, egg, shellfish or preservatives.

Formulation re: Vegetarian/Vegan

Vegetarian/Vegan Product.

FDA Statements

FDA Statement of Identity

A Dietary Supplement

FDA Disclaimer Statement

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

General Statements: All Other Content

SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate aches and pains resulting from overexertion or stress. Therefore, SAMe is an all natural product that can be part of a nutritional program for pain management. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the regulation of mood.

Brand IP Statement(s) re: (c), (TM), (SM)

NOW(R) SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.*

General Statements: All Other Content

ACTUAL SIZE

General Statements: All Other Content

NERVOUS SYSTEM SUPPORT • Supports Emotional Well-Being • Supports Joint Health*

Seals/Symbols

GMP QUALITY ASSURED

General Statements: All Other Content

ENTERIC COATED

General Statements: All Other Content

Please Recycle. Product of India.

General: Product/Version Code

CODE 0141 V3

Manufacturer & Distributor

Distributor

NOW Foods

395 S. Glen Ellyn Rd., Bloomingdale, IL, 60108, USA

Market Reference

$7.33 – $119.99· 40 listings
  • NOW Foods SAMe 400 mg 60 Tablets

    Fruitful Yield4.7(417)
    $45.99
  • NOW SAMe 400mg Tablets

    Village Vitamin Store4.7(417)
    $36.56
  • (2 pack) NOW Foods SAMe Nervous System Support, 400mg, 30 Ct, Size: 3.45

    Walmart - Fruitful Yield4.7(417)
    $50.52
  • NOW Softgels with Vitamin E-400

    NOW4.8(12000)
    $25.99
  • NOW Foods Vitamin E-400 With Mixed Tocopherols

    NOW4.8(12000)
    $19.99
  • NOW Foods Sun-E 400 Softgels

    iHerb4.8(327)
    $16.52
  • Nature Made SAM-e Complete 400 mg

    Walmart4.6(190)
    $52.97
  • Now Foods Magnesium 400 Mg 180 Capsules

    Meijer3.0(4)
    $21.99

Where to Buy Locally

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Research & Studies

  • … of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …

    BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer

    … The test article used in the present study has a dosage strength of 400 mg (based on the weight of the free base). The SAM-e counter-ions are disulfate tosylate and the overall tablet …

    202014 citations
  • Safety and efficacy of S-adenosylmethionine (SAMe) for osteoarthritis

    KL Soeken, WL Lee, RB Bausell, M Agelli… - J Fam Pract, 2002 - cdn.mdedge.com

    … (SAMe), a dietary supplement now available in the United … 1999 as a dietary supplement to promote joint health, mobility, … 600 mg per day orally17,21,25; and one used 400 mg per …

    2002174 citations
  • S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial.[ISRCTN36233495]

    WI Najm, S Reinsch, F Hoehler, JS Tobis… - BMC musculoskeletal …, 2004 - Springer

    … S-Adenosylmethionine (SAMe) is a dietary supplement used … On most functional health measures both groups showed a … An ANOVA on pain-today scores in SAMe treated subjects with …

    2004213 citations
  • A role for supplements in optimizing health: the metabolic tune-up

    BN Ames - Archives of biochemistry and biophysics, 2004 - Elsevier

    An optimum intake of micronutrients and metabolites, which varies with age and genetic constitution, would tune up metabolism and give a marked increase in health, particularly for the …

    2004189 citations
  • A decade of nutraceutical patents: where are we now in 2018?

    P Daliu, A Santini, E Novellino - Expert opinion on therapeutic …, 2018 - Taylor & Francis

    … of a food that has medical or health benefits, including the … be considered in the same way as for any food supplement or … in the range between 400 mg/day and 700 mg/day. Again in …

    2018164 citations
  • The supplement handbook: a trusted expert's guide to what works & what's worthless for more than 100 conditions

    M Moyad, J Lee - 2014 - books.google.com

    … Now, more than 20 years later, I have the same position, but the endowment has grown substantially … I think the time has arrived for supplements to be included in these everyday health …

    201417 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-10-25. DSLD Label ID: 13083. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.