SAMe 200 mg®

Other Combinations

Brand: NOW

Tablet or PillOther CombinationsOff Market
Click to view full label

Net Contents

30 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 33739 00137 5

Product Version

CODE 0137B V5

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

4Active Ingredients

4 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3% Daily Value Coverage

3 ingredients report a %DV; 2 meet or exceed 100% DV.

3Dietary Attributes

Label states: Vegan, Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Tablet(s) · 2–4 per day

IngredientAmount Per Serving% Daily Value
Vitamin B6(Pyridoxine Hydrochloride)2 mg100%
Folic Acid200 mcg50%
Vitamin B12(Cyanocobalamin)50 mcg833%
SAMe(S-Adenosyl-L-Methionine Disulfate Tosylate)200 mg

Not Present

Other Ingredients

CelluloseCroscarmellose SodiumMagnesium StearateSilicaStearic AcidAscorbic AcidCitric AcidEnteric Coating

Target Groups

VeganVegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 tablet 2 to 4 times daily, preferably on an empty stomach.

Warnings & Precautions

Precautions re: All Other

Caution: For adults only.

Precautions re: Pregnant or Nursing or Prescription Medications

Individuals with bipolar depression, anxiety disorders or taking antidepressant medications should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Precautions re: Children

Keep out of reach of children.

Precautions re: Allergies

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Precautions re: All Other

Do Not Eat Freshness Packets. Keep in Bottle.

Storage

Storage

Refrigeration recommended after opening.

Formulation

Formula re: Contains

With B-Vitamin Cofactors

Formulation re: Vegetarian/Vegan

Vegetarian/Vegan

Formulation re: Does NOT Contain

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients.

FDA Statements

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

A Dietary Supplement

Other Label Statements

General Statements: All Other Content

SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health.* SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism.*

Brand IP Statement(s) re: (c), (TM), (SM)

NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.*

General: Product/Version Code

CODE 0137B V5

General Statements: All Other Content

Nervous System Support* Supports Cartilage Production

General Statements: All Other Content

ENTERIC COATED

General Statements: All Other Content

Amino Acids

General Statements: All Other Content

Family owned since 1968.

Seals/Symbols

GMP QUALITY ASSURED

Manufacturer & Distributor

Manufacturer

NOW Foods

395 S. Glen Ellyn Rd., Bloomingdale, IL, 60108, USA

Market Reference

$4.99 – $84.50· 40 listings
  • Now Foods SAMe 200 mg 60 Veg Capsules

    Vitacost.com4.7(437)
    $24.48
  • NOW Foods SAMe 200 mg 60 Veg Capsules

    Dr. Judy Morgan's Naturally Healthy Pets4.6(14)
    $39.99
  • (2 pack) NOW Foods Supplement, SAMe (Disulfate Tosylate), Nervous System Support, 200 mg, 60 Veg Capsules, Size: 4.00

    Walmart - Fruitful Yield4.6(14)
    $45.32
  • NOW SAMe Stabilized 200mg 60 Veggie Caps

    vitaminsuk.com US4.6(14)
    $43.00
  • (2 pack) NOW Foods SAMe, Disulfate Tosylate, 200 mg, 120 Veg Capsules, Size: 4.50

    Walmart - Fruitful Yield4.6(14)
    $75.66
  • Now Foods E-1000 Mixed Tocopherols

    Walmart - iHerb4.8(660)
    $10.55
  • Nature Made SAM-e Complete 400 mg

    Target4.5(45)
    $57.54
  • Now Omega 3

    Muscle & Strength4.7(5400)
    $12.49

Where to Buy Locally

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Research & Studies

  • Safety and efficacy of S-adenosylmethionine (SAMe) for osteoarthritis

    KL Soeken, WL Lee, RB Bausell, M Agelli… - J Fam Pract, 2002 - cdn.mdedge.com

    … (SAMe), a dietary supplement now available in the United … as a dietary supplement to promote joint health, mobility, and … Italy and is available in 200 mg and 400 mg doses.) Recent …

    2002174 citations
  • S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial.[ISRCTN36233495]

    WI Najm, S Reinsch, F Hoehler, JS Tobis… - BMC musculoskeletal …, 2004 - Springer

    … On most functional health measures both groups showed a … (SAMe) used in this study was enteric coated 200 mg tablets … An ANOVA on pain-today scores in SAMe treated subjects with …

    2004213 citations
  • What about supplements for osteoarthritis? A critical and evidenced‐based review

    ES Vista, CS Lau - International Journal of Rheumatic …, 2011 - Wiley Online Library

    … These OA supplements have now been considered by many patients and even healthcare … ), glucosamine and CS combined (same doses), a placebo, or a 200 mg dose of NSAID as a …

    201152 citations
  • The role of nutrition and nutritional supplements in women's health

    MM Seibel - Fertility and sterility, 1999 - Elsevier

    … Result(s): Studies on nutrition and nutritional supplements in women’s health are found … and nutritional supplements may reduce or prevent illness, saving the health care system …

    199932 citations
  • First St. John's Wort, Now SAM-e: Is Society as a Whole at Risk Without FDA Regulation of Psychiatric Self-Medication?

    LM Diaz - Kansas Journal of Law & Pubic Policy, 1999 - papers.ssrn.com

    … psychiatric help to instead stroll down the aisle of their favorite health food store and select a dietary supplement to alleviate their symptoms. The statement is true; it is senseless. …

    19992 citations
  • A role for supplements in optimizing health: the metabolic tune-up

    BN Ames - Archives of biochemistry and biophysics, 2004 - Elsevier

    An optimum intake of micronutrients and metabolites, which varies with age and genetic constitution, would tune up metabolism and give a marked increase in health, particularly for the …

    2004189 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2015-11-24. DSLD Label ID: 53388. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.