M.S.M. Methylsulfonylmethane

Suggested Use

Recommendation: As a dietary supplement; take 1/2 teaspoon two times each day per 100 pounds of body weight; early morning and early afternoon. Mix in 3 or 4 ounces of water or juice. Tends to lump and harden but does not effect quality.

• 

  GNC MSM Capsules

  GNC4.7(38)

  $26.99
• 

  (2 pack) NOW Supplements, MSM (Methylsulfonylmethane) Powder, Supports Healthy Cartilage*, Joint Health*, 8-Ounce, Size: 2.70 x 2.70 x 4.75, White

  Walmart - Fruitful Yield5.0(7)

  $22.78
• 

  BulkSupplements MSM Capsules

  Target4.8(1800)

  $17.97
• 

  Select MSM Joint Support

  Valley Vet Supply4.8(316)

  $18.95
• 

  SAN MSM 1000mg 120 Capsules

  San Nutrition

  $18.49
• 

  Now Foods MSM Powder Joint Health Dietary Supplement

  PureFormulas.com4.7(1400)

  $15.46
• 

  BulkSupplements MSM Powder

  Walmart - BulkSupplements.com4.8(1800)

  $19.97
• 

  Natural Balance Pure MSM Liquid

  iHerb4.6(19)

  $18.69

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• GNC

  3.6 (62)

  Vitamin & supplements store

  904 Audelia Rd, Richardson, TX 75081

  Directions(972) 234-2386

• 5 Star Nutrition Dallas

  4.9 (338)

  Vitamin & supplements store

  11260 N Central Expy Ste 200, Dallas, TX 75243

  Directions(214) 238-0444

• Great Earth Vitamins

  4.8 (42)

  Vitamin & supplements store

  1011 Northwest Hwy B, Garland, TX 75041

  Directions(972) 840-6144

• The Vitamin Shoppe

  4.4 (178)

  Vitamin & supplements store

  1001 N Central Expy #100, Plano, TX 75075

  Directions(972) 422-4106

• HercSupps of Plano

  5.0 (203)

  Vitamin & supplements store

  1201 E Spring Creek Pkwy #140, Plano, TX 75074

  Directions(469) 215-9051

• Nutrition Nation

  5.0 (23)

  Vitamin & supplements store

  3501 Towne Crossing Blvd, Mesquite, TX 75150

  Directions(972) 863-7241

• The Vitamin Shoppe

  4.5 (198)

  Vitamin & supplements store

  5425 Greenville Ave, Dallas, TX 75206

  Directions(214) 750-8064

• GNC

  3.8 (63)

  Vitamin & supplements store

  140 Cedar Sage Dr, Garland, TX 75040

  Directions(972) 496-2607

• Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing

  N Muizzuddin, R Benjamin - International Journal for Vitamin …, 2020 - econtent.hogrefe.com

  … The results of this study suggest that MSM taken orally may be beneficial for skin health and the reduction of fine lines and wrinkles, at a dose as low as 1 grams a day. …

  202035 citations

• Protective Effect of Methyl Sulfonyl Methane on the Progression of Age-Induced Bone Loss by Regulating Oxidative Stress-Mediated Bone Resorption

  D Zhang, L Wang, L Tang, Y Zhang, H Zhang, L Zou - Antioxidants, 2025 - mdpi.com

  … to supplement the … MSM treatment enhanced the mRNA expression of osteocyte-specific genes such as Sost and Col1a1, further supporting the positive effects of MSM on bone health. …

  2025

• Effects of oral supplementation with methylsulfonylmethane on skin health and wrinkle reduction

  M Anthonavage, RL Benjamin, ED Withee - Nat. Med. J, 2015 - lehvoss-nutrition.com

  … effectiveness of methylsulfonylmethane (MSM) as an oral supplement on skin health using … morning as needed, with reapplication prior to sun exposure at the participant’s discretion. …

  201524 citations

• Dietary polyphenol and methylsulfonylmethane supplementation improves immune, DAMP signaling, and inflammatory responses during recovery from all-out …

  BK McFarlin, DW Hill, JL Vingren, JH Curtis… - Frontiers in …, 2021 - frontiersin.org

  … MSM supplement in the present study) translates into a better functioning recovery process and a more rapid return to activity. With the advent of new … using a supplement that combined …

  202112 citations

• Methylsulfonylmethane improves knee quality of life in participants with mild knee pain: a randomized, double-blind, placebo-controlled trial

  A Toguchi, N Noguchi, T Kanno, A Yamada - Nutrients, 2023 - mdpi.com

  … that MSM oral consumption improved both knee and systemic health conditions in healthy … MSM has been suggested as a supplement for the prevention of OA due to its pleiotropic …

  202329 citations

• The miracle of MSM: the natural solution for pain

  SW Jacob - 1999 - books.google.com

  … MSM stands for methylsulfonylmethane, a natural substance present in food and in the … is that MSM is readily available as an inexpensive nutritional supplement in health food stores, …

  199973 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-10-01. DSLD Label ID: 11910. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.