Formula 4 Protease

Non-Nutrient / Non-Botanical

Brand: NESS Nutritional Enzyme Support System

CapsuleNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

90 Capsule(s)

Serving Size

3 Capsule(s)

Servings Per Container

30

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 07636 03141 4

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Wheat
  • Soy
  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 3 Capsule(s) · 1– per day

IngredientAmount Per Serving
Proprietary Vegetarian Enzyme Blend440 mg
Protease

Not Present

Other Ingredients

Other Ingredients

Plant FiberGelatinWater

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommended Usage: One capsule with each meal, three capsules between meals, or more may be taken according to need. Take with adequate liquid.

Warnings & Precautions

Precautions re: All Other

Use only if tamper-evident seal is unbroken.

Precautions re: Children

Keep out of reach of children.

Precautions re: All Other

This product is not recommended for anyone with gastritis or ulcers.

Storage

Storage

Store tightly sealed in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Contains no aspartame, sucrose, sorbitol, gluten, nuts, salt, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.

FDA Statements

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure or prevent any disease.

FDA Statement of Identity

enzyme supplement

Other Label Statements

General Statements: All Other Content

NUTRITIONAL ENZYME SUPPORT SYSTEM

Brand IP Statement(s) re: (c), (TM), (SM)

NESS Protease is uniquely formulated to help optimize the digestion of protein minimizing protein intolerance and promotes systemic balance when taken between meals.*

Manufacturer & Distributor

Distributor

enzymes, inc

Kansas City, MO, 64153, U.S.A.

800-637-7893

Market Reference

$9.20 – $119.98· 33 listings
  • Ness Enzymes Protease #4 180 Capsules

    Supplement First5.0(4)
    $34.00
  • Ness Enzymes Protease Formula 4 90 Capsules

    Nutriessential.com5.0(3)
    $34.20
  • Ness Enzymes Protease with Calcium

    Covenant Health Products5.0(1)
    $38.99
  • Ness Enzymes Protease Cal-Mag 90 Caps

    PureFormulas.com5.0(3)
    $33.33
  • Ness Enzymes Digest Formula 20 90 Capsules

    Supplement First5.0(5)
    $30.00
  • Protease Enzymes

    Renu Herbs
    $79.95
  • Protease 120 Capsules

    Natural Healthy Concepts4.8(4)
    $46.99
  • Ness Enzymes Digest Chewables 180 Tablets

    Professional Supplement Center5.0(6)
    $47.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Research & Studies

  • … microbial protease supplementation increases net postprandial plasma amino acid concentrations after pea protein ingestion in healthy adults: a randomized …

    KJM Paulussen, AT Askow, MT Deutz, CF McKenna… - … Journal of nutrition, 2024 - Elsevier

    … Digestibility is a primary factor in determining the quality of dietary protein. Microbial protease supplementation may be a strategy for improving protein digestion and subsequent …

    202412 citations
  • Oral multi-enzyme supplementation alters postprandial plasma nutrient concentrations after a mixed meal in healthy middle-aged and older adults: a …

    MT Deutz, AT Askow, SM Garvey, DA Alvarado… - … Journal of Nutrition, 2026 - Elsevier

    Background Age-related decline in digestive function increases malnutrition risk. Supplementing meals with digestive enzymes may improve macronutrient digestion and bioavailability …

    2026
  • Digestive enzyme supplementation in gastrointestinal diseases

    G Ianiro, S Pecere, V Giorgio… - Current drug …, 2016 - ingentaconnect.com

    … as enzymes, are able to promote absorption of dietary lipids by … their respective function: proteolytic enzymes (mainly trypsinogen … irreversibly denatured when exposed to pH =4 13, 14]. …

    2016228 citations
  • Functional Properties of Enzymatic Food Protein Hydrolysates

    D Kadam, RE Aluko - Annual Review of Food Science and …, 2025 - annualreviews.org

    … in process optimization, bitterness mitigation, and regulatory … This property is especially valuable in medical nutrition and … of proteases is an important strategy for enhancing enzyme …

    2025
  • enzymatic Preparation of low-Phenylalanine Formula Derived from Skim Milk Hydrolysate for Phenyl ketonuric Patients

    AE Shehata, MNI El-Magdoub, TM Kamal… - … Journal of Medical …, 2008 - ajol.info

    … was effective in supplying most of the needed dietary intakes … lized purified proteolytic enzymes for enzymatic hydrolysis based … (BaSO4) but bitterness depletion was achieved more by …

    20088 citations
  • Principles of enzymology for the food sciences

    JR Whitaker - 2018 - api.taylorfrancis.com

    … of the parameters which affect enzyme activity (Chapters 4-13) while … Enzymes are hydrolyzed by proteolytic enzymes which … of enzymes to this aspect of the food, nutritional, and health …

    20181,393 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-04-26. DSLD Label ID: 7472. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.