Formula 4 Protease™

Non-Nutrient / Non-Botanical

Brand: NESS Nutritional Enzyme Support System

CapsuleNon-Nutrient/Non-BotanicalOff Market

Product label for Formula 4 Protease — Click to view full label

Net Contents

90 Vegetarian Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

Supplement Form

Capsule

Bar Code (UPC/SKU)

Not specified

Product Version

(v1)

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

Milk
Wheat
Soy

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1 per day

Ingredient	Amount Per Serving
Protease	193 mg	—

Not Present

Other Ingredients

Plant FiberWater

Target Groups

Adult (18 - 50 Years)Dairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommended Use: Take one capsule at the beginning of each meal with adequate liquid, or as directed by your healthcare professional.

Warnings & Precautions

Precautions re: All Other

Use only if tamper-evident seal is unbroken.

Precautions re: Children

Keep out of reach of children.

Storage

Store tightly closed in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Contains no aspartame, sugar, salt, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.

FDA Statements

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure or prevent any disease

FDA Statement of Identity

enzyme supplement

Other Label Statements

Brand IP Statement(s) re: (c), (TM), (SM)

NESS(TM) Protease is uniquely formulated to help optimize the digestion of protein, minimizing protein intolerance and promoting systemic balance when taken between meals.

General Statements: All Other Content

NUTRITIONAL ENZYME SUPPORT SYSTEM

Manufacturer & Distributor

Manufacturer

enzymes, inc.

Kansas City, MO, 64153, U.S.A.

800-228-1501

Market Reference

$9.20 – $119.98· 33 listings

Ness Enzymes Protease #4 180 Capsules
Supplement First5.0(4)
$34.00
Ness Enzymes Protease Formula 4 90 Capsules
Nutriessential.com5.0(3)
$34.20
Protease #4
Curated Wellness5.0(4)
$38.00
Ness Enzymes Protease with Calcium
PureFormulas.com5.0(1)
$33.33
Ness Enzymes Digest Formula 20 90 Capsules
Supplement First5.0(5)
$30.00
Ness Enzymes Protease Cal-Mag 90 Caps
PureFormulas.com5.0(3)
$33.33
Protease Enzymes
Renu Herbs
$79.95
Ness Enzymes Digest Chewables 180 Tablets
Furnster.de5.0(6)
$12.38

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

The Vitamin Shoppe
4.6 (65)
Vitamin & supplements store
439 Boardman Poland Rd, Boardman, OH 44512
Directions (330) 965-0697
The Vitamin Depot
4.6 (13)
Vitamin & supplements store
620 South Ave, Tallmadge, OH 44278
Directions (330) 208-2711
Vitamin World -- In-Store Shopping or Curbside Pickup
4.0 (4)
Vitamin & supplements store
7401 Market St #779, Youngstown, OH 44512
Directions (330) 729-9037
GNC
3.7 (39)
Vitamin & supplements store
5880 Mahoning Ave #12, Austintown, OH 44515
Directions (330) 270-0180
Vitanet, LLC
4.3 (27)
Vitamin & supplements store
887 Edison St NW, Hartville, OH 44632
Directions (330) 877-8786
USANA Distributor | Website Order
5.0 (1)
Vitamin & supplements store
9519 E Market St, Warren, OH 44484
Directions
Pure Health Core LLC
5.0 (1)
Vitamin & supplements store
187 Diamond Way, Cortland, OH 44410
Directions (313) 300-7814
The Vitamin Shoppe
4.5 (176)
Vitamin & supplements store
5704 Youngstown Warren Rd, Niles, OH 44446
Directions (330) 349-9050

Research & Studies

… microbial protease supplementation increases net postprandial plasma amino acid concentrations after pea protein ingestion in healthy adults: a randomized …
KJM Paulussen, AT Askow, MT Deutz, CF McKenna… - … Journal of nutrition, 2024 - Elsevier
… Digestibility is a primary factor in determining the quality of dietary protein. Microbial protease supplementation may be a strategy for improving protein digestion and subsequent …
202412 citations
Oral multi-enzyme supplementation alters postprandial plasma nutrient concentrations after a mixed meal in healthy middle-aged and older adults: a …
MT Deutz, AT Askow, SM Garvey, DA Alvarado… - … Journal of Nutrition, 2026 - Elsevier
Background Age-related decline in digestive function increases malnutrition risk. Supplementing meals with digestive enzymes may improve macronutrient digestion and bioavailability …
2026
Digestive enzyme supplementation in gastrointestinal diseases
G Ianiro, S Pecere, V Giorgio… - Current drug …, 2016 - ingentaconnect.com
… as enzymes, are able to promote absorption of dietary lipids by … their respective function: proteolytic enzymes (mainly trypsinogen … irreversibly denatured when exposed to pH =4 13, 14]. …
2016228 citations
Functional Properties of Enzymatic Food Protein Hydrolysates
D Kadam, RE Aluko - Annual Review of Food Science and …, 2025 - annualreviews.org
… in process optimization, bitterness mitigation, and regulatory … This property is especially valuable in medical nutrition and … of proteases is an important strategy for enhancing enzyme …
2025
enzymatic Preparation of low-Phenylalanine Formula Derived from Skim Milk Hydrolysate for Phenyl ketonuric Patients
AE Shehata, MNI El-Magdoub, TM Kamal… - … Journal of Medical …, 2008 - ajol.info
… was effective in supplying most of the needed dietary intakes … lized purified proteolytic enzymes for enzymatic hydrolysis based … (BaSO4) but bitterness depletion was achieved more by …
20088 citations
Principles of enzymology for the food sciences
JR Whitaker - 2018 - api.taylorfrancis.com
… of the parameters which affect enzyme activity (Chapters 4-13) while … Enzymes are hydrolyzed by proteolytic enzymes which … of enzymes to this aspect of the food, nutritional, and health …
20181,393 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-10-10. DSLD Label ID: 37565. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.