Formula 4 Protease®
Non-Nutrient / Non-BotanicalBrand: NESS Nutritional Enzyme Support System
Functions
Net Contents
180 Vegetarian Capsule(s)
Serving Size
1 Vegetarian Capsule(s)
Servings Per Container
180
Supplement Form
Capsule
Bar Code (UPC/SKU)
7 07636 03142 1
Product Version
03-109-01
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegetarian, Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Wheat
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Vegetarian Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| Protease | 193 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Recommended Use: Take one (1) capsule at the beginning of each meal for digestive support or twice daily on an empty stomach for systemic support, or as directed by your healthcare professional.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your physician before use.
Precautions re: All Other
Use only if tamper evident seal is unbroken.
Precautions re: Children
Keep out of reach of children.
Storage
Storage
Store tightly closed in a cool, dry place.
Formulation
Formulation re: Other
Formulated exclusively for healthcare professionals NESS Protease helps optimize the digestion of protein, minimizing protein intolerance when taken with a meal or helps promote systemic balance when taken between meals.
Formulation re: Does NOT Contain
Non-GMO
Formulation re: Vegetarian/Vegan
Vegetarian
Formulation re: Other
GMP compliant
Formulation re: Does NOT Contain
Contains No: Aspartame, sugar, salt, gluten, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.
FDA Statements
FDA Disclaimer Statement
These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure or prevent any disease.
FDA Statement of Identity
Enzyme Supplement
Manufacturer & Distributor
Manufacturer
Enzymes Inc.
Kansas City, MO, 64153, U.S.A.
1-800-637-7893
Market Reference
Ness Enzymes Protease #4 180 Capsules
Supplement First5.0(4)$34.00Ness Enzymes Protease Formula 4 90 Capsules
Nutriessential.com5.0(3)$34.20Protease #4
Curated Wellness5.0(4)$38.00Ness Enzymes Protease with Calcium
PureFormulas.com5.0(1)$33.33Ness Enzymes Digest Formula 20 90 Capsules
Supplement First5.0(5)$30.00Ness Enzymes Protease Cal-Mag 90 Caps
PureFormulas.com5.0(3)$33.33Protease Enzymes
Renu Herbs$79.95Ness Enzymes Digest Chewables 180 Tablets
Furnster.de5.0(6)$12.38
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Walgreens
3.6 (39)Vitamin & supplements store
310 Story St, Boone, IA 50036
Tractor Supply Co.
4.2 (195)Animal feed store
1125 SE Marshall St, Boone, IA 50036
Fit Pharm Nutrition
5.0 (33)Vitamin & supplements store
2010 SE Delaware Ave Ste 226, Ankeny, IA 50021
Fit Pharm Nutrition- Weight Loss, Sports Nutrition, Vitamins,
4.5 (188)Vitamin & supplements store
6305 Mills Civic Pkwy Suite 3109, West Des Moines, IA 50266
GNC
3.6 (20)Vitamin & supplements store
2801 Grand Ave, Ames, IA 50010
5 Star Nutrition Urbandale
4.9 (210)Vitamin & supplements store
11881 Hickman Rd Suite 200, Urbandale, IA 50323
Walmart Supercenter
3.9 (1745)Department store
1515 SE Marshall St, Boone, IA 50036
Campbell's Nutrition
4.5 (49)Vitamin & supplements store
2749 100th St, Urbandale, IA 50322
Research & Studies
… microbial protease supplementation increases net postprandial plasma amino acid concentrations after pea protein ingestion in healthy adults: a randomized …
KJM Paulussen, AT Askow, MT Deutz, CF McKenna… - … Journal of nutrition, 2024 - Elsevier
… Digestibility is a primary factor in determining the quality of dietary protein. Microbial protease supplementation may be a strategy for improving protein digestion and subsequent …
202412 citationsOral multi-enzyme supplementation alters postprandial plasma nutrient concentrations after a mixed meal in healthy middle-aged and older adults: a …
MT Deutz, AT Askow, SM Garvey, DA Alvarado… - … Journal of Nutrition, 2026 - Elsevier
Background Age-related decline in digestive function increases malnutrition risk. Supplementing meals with digestive enzymes may improve macronutrient digestion and bioavailability …
2026Digestive enzyme supplementation in gastrointestinal diseases
G Ianiro, S Pecere, V Giorgio… - Current drug …, 2016 - ingentaconnect.com
… as enzymes, are able to promote absorption of dietary lipids by … their respective function: proteolytic enzymes (mainly trypsinogen … irreversibly denatured when exposed to pH =4 13, 14]. …
2016228 citationsEnzyme nutrition: the food enzyme concept
E Howell - 1995 - books.google.com
… to our present health crisis-food enzymes. The study of food … that the organism's three main enzymes, protease, lipase, and … in a given case of infant sickness or death. Shahani et al., in "…
1995163 citationsFunctional Properties of Enzymatic Food Protein Hydrolysates
D Kadam, RE Aluko - Annual Review of Food Science and …, 2025 - annualreviews.org
… in process optimization, bitterness mitigation, and regulatory … This property is especially valuable in medical nutrition and … of proteases is an important strategy for enhancing enzyme …
2025enzymatic Preparation of low-Phenylalanine Formula Derived from Skim Milk Hydrolysate for Phenyl ketonuric Patients
AE Shehata, MNI El-Magdoub, TM Kamal… - … Journal of Medical …, 2008 - ajol.info
… was effective in supplying most of the needed dietary intakes … lized purified proteolytic enzymes for enzymatic hydrolysis based … (BaSO4) but bitterness depletion was achieved more by …
20088 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-05-22. DSLD Label ID: 221225. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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