Formula 4 Protease®

Non-Nutrient / Non-Botanical

Brand: NESS Nutritional Enzyme Support System

CapsuleNon-Nutrient/Non-BotanicalOn Market

Functions

Digestive & Gut

Product label for Formula 4 Protease — Click to view full label

Net Contents

90 Vegetarian Capsule(s)

Serving Size

1 Vegetarian Capsule(s)

Servings Per Container

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 07636 03141 4

Product Version

03-108-01

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3Dietary Attributes

Label states: Vegetarian, Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

Milk
Wheat
Soy
Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Vegetarian Capsule(s) · 1– per day

Ingredient	Amount Per Serving
Protease	193 mg	—

Not Present

Other Ingredients

Plant FiberWater

Target Groups

VegetarianAdult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommended Use: Take one (1) capsule at the beginning of each meal for digestive support or twice daily on an empty stomach for systemic support, or as directed by your healthcare professional.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your physician before use.

Precautions re: All Other

Use only if tamper evident seal is unbroken

Precautions re: Children

Keep out of reach of children.

Storage

Store tightly closed in a cool, dry place.

Formulation

Formulation re: Other

Formulated exclusively for healthcare professionals NESS Protease helps optimize the digestion of protein, minimizing protein intolerance when taken with a meal or helps promote systemic balance when taken between meals.

Formulation re: Does NOT Contain

Non-GMO

Formulation re: Vegetarian/Vegan

Vegetarian

Formulation re: Other

GMP compliant

Formulation re: Does NOT Contain

Contains No: Aspartame, sugar, salt, gluten, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.

FDA Statements

FDA Disclaimer Statement

These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure or prevent any disease.

FDA Statement of Identity

Enzyme Supplement

Manufacturer & Distributor

Manufacturer

Enzymes Inc.

Kansas City, MO, 64153, U.S.A.

1-800-637-7893

Market Reference

$21.00 – $119.98· 30 listings

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Ness Enzymes Digest Formula 20 500 Capsules
PureFormulas.com5.0(5)
$63.16
Protease Formula (180 Cap) Sale
The Natural Apothecary Shoppe
$53.95

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

The Vitamin Shoppe
4.3 (127)
Vitamin & supplements store
661 W 181st St, New York, NY 10033
Directions (212) 927-2849
Nutri - Life Nutritional Center
4.6 (17)
Vitamin & supplements store
1469 St Nicholas Ave, New York, NY 10033
Directions (212) 740-2221
GNC
4.3 (110)
Vitamin & supplements store
3799 Broadway, New York, NY 10032
Directions (212) 368-5385
Nutriciòn Hernesmia
5.0 (4)
Vitamin & supplements store
501 W 164th St, New York, NY 10032
Directions (917) 769-0933
The Vitamin Shoppe
4.4 (103)
Vitamin & supplements store
2100 88th St F4, North Bergen, NJ 07047
Directions (201) 758-0404
GNC
4.5 (178)
Vitamin & supplements store
215 W 125th St, New York, NY 10027
Directions (212) 280-1021
The Vitamin Shoppe
4.2 (90)
Vitamin & supplements store
12 The Promenade, Edgewater, NJ 07020
Directions (201) 945-5967
The Vitamin Shoppe
4.5 (140)
Vitamin & supplements store
5510 Broadway, Bronx, NY 10463
Directions (718) 884-2984

Research & Studies

… microbial protease supplementation increases net postprandial plasma amino acid concentrations after pea protein ingestion in healthy adults: a randomized …
KJM Paulussen, AT Askow, MT Deutz, CF McKenna… - … Journal of nutrition, 2024 - Elsevier
… Digestibility is a primary factor in determining the quality of dietary protein. Microbial protease supplementation may be a strategy for improving protein digestion and subsequent …
202413 citations
Oral multi-enzyme supplementation alters postprandial plasma nutrient concentrations after a mixed meal in healthy middle-aged and older adults: a …
MT Deutz, AT Askow, SM Garvey, DA Alvarado… - … Journal of Nutrition, 2026 - Elsevier
Background Age-related decline in digestive function increases malnutrition risk. Supplementing meals with digestive enzymes may improve macronutrient digestion and bioavailability …
2026
Digestive enzyme supplementation in gastrointestinal diseases
G Ianiro, S Pecere, V Giorgio… - Current drug …, 2016 - ingentaconnect.com
… as enzymes, are able to promote absorption of dietary lipids by … their respective function: proteolytic enzymes (mainly trypsinogen … irreversibly denatured when exposed to pH =4 13, 14]. …
2016228 citations
Enzyme nutrition: the food enzyme concept
E Howell - 1995 - books.google.com
… to our present health crisis-food enzymes. The study of food … that the organism's three main enzymes, protease, lipase, and … in a given case of infant sickness or death. Shahani et al., in "…
1995163 citations
Early‐Life Protein Nutrition and Enzymatic Regulation: Mechanistic Pathways Linking Growth Faltering, Stunting, and Obesity
P Batra, D Kaushik, P Rasane, M Kumar - The FASEB Journal, 2026 - Wiley Online Library
… enzymes such as pepsin activation, pancreatic proteases (… Integrative interventions like balanced protein formulas, … During fasting or severe illness, cortisol level can rapidly stimulate the …
20262 citations
Functional Properties of Enzymatic Food Protein Hydrolysates
D Kadam, RE Aluko - Annual Review of Food Science and …, 2025 - annualreviews.org
… in process optimization, bitterness mitigation, and regulatory … This property is especially valuable in medical nutrition and … of proteases is an important strategy for enhancing enzyme …
20251 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-05-22. DSLD Label ID: 221220. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.