Dr. Joints Advanced™

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 3 Dr. Joints Advanced capsules once daily and with a meal. To be used as part of a healthy lifestyle consisting of regular physical activity and a proper diet.

Storage

Store in a cool dry place. Avoid excessive heat.

Formulation re: Other

Joint health formula Supports: Mobility Flexibility Anti-inflammation

Formulation re: Does NOT Contain

Stim Free

Formulation re: Other

Fast acting formula that works in as little as 7 days Dr. Joints Advanced is an effective joint health supplement formulated with ingredients shown to reduce joint discomfort, increase mobility, and help maintain healthy cartilage.

Formula re: Contains

Fruitex-B [calcium fructoborate] 1,2,3,4 Clinically proven and patented plant-based mineral complex studied for its ability to reduce joint discomfort and certain inflammatory markers. Multiple published human clinicals on its unique properties and potential health benefits. Fast-acting joint and mobility support; promoting joint comfort and improved function in as little as 7 days. Benefits for joints and flexibility when used alone, with additional synergies when used in combination with glucosamine and chondroitin. 1. Reyes-Izquierdo et al. (2011). Short-term intake of calcium fructoborate improves WOMAC and McGill scores and beneficially modulates biomarkers associated with knee osteoarthritis: A pilot clinical double-blind placebo-controlled study. American Journal of Biomedical Science. ISSN: 1937-9080. 2. Scorei et al.(2011). A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis. BioI Trace Elem Res. 144:253-263. 3. Reyes-Izquierdo T et al. (2014). Short-term efficacy of a combination of glucosamine and chondroitin sulfate compared to a combination of glucosamine, chondroitin sulfate and calcium fructoborate (CFB) on improvement of knee discomfort conditions in healthy subjects. A comparative, double-blind, placebo controlled acute clinical study. Journal of Aging Research & Clinical Practice. 3(4):223-228. 4. Pietrzkowski Z, et al.(2014). Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative double-blind, placebo-controlled clinical study. Clinical Interventions in Aging. 9:895-899. Additional joint health ingredients Glucosamine sulfate + chondroitin 5,6,7,8,9 Glucosamine is a natural compound found in the body, but levels tend to decline with age. Chondroitin is a compound found naturally in human connective tissue. These ingredients have been shown to improve symptoms of joint discomfort and functionality. When used in combination the two can have an even greater overall effect. 5. Uebelheart D, Malaise M, Marcolongo R, et al.(2004) Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: A one-year, randomize double-blind, multicenter study versus placebo. Osteoarthritis Cartilage. 12:269-76. 6. Kahan A. (2006) Study on Osteoarthritis Progression Prevention: a new two-year trial with chondroitin 4&6 sulfate (CS). Available at: www.ibsa-ch.com/eular_2006_amsterdam_vignon-2.pdf. 7. McAlindon TE, LaValley MP, Gulin JP, Felson DT. (2000) Glucosamine and chondroitin for treatment of osteoarthritis: a systemic quality assessment and meta-analysis. JAMA. 283(11):1469-75. 8. Kelly GS. (1998) The role of glucosamine sulfate and chondroitin sulfates in the treatment of degenerative joint disease. Altern Med Rev. 3(1):27-39. 9. Pavelka k, et al. (2002). Glucosamine sulfate use and delay of progression of knee osteoarthritis. Arch Internal Med. 162(18):2113-23. Cetyl-Myristoleate 10,11 Cetyl Myristoleate is a fatty acid reported to function in multiple ways: as a lubricant, as an immune system modulator, and as an anti-inflammatory agent. Studies have shown its ability to improve joint function and mobility. 10. Siemandi, H. (1997) The effect of Cis-9-Cetyl Myristoleate (CMO) and adjunctive therapy on arthritis and auto immune disease: a randomized trial. Townsend Letter for Doctors and Patients. Aug/Sept: 58-63. 11. Diehl HW, May EL. (1994) Cetyl Myristoleate (CMO) isolated from Swiss albino mice: an apparent protective agent against adjuvant arthritis in rats. J Pharm Sci. 83(3):296-9.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements: All Other Content

Low Stim Medium Stim High Stim Use this stim meter for Dr. Joints Advanced to assess if this product suits your tolerance levels for stimulant-based ingredients.

General Statements: All Other Content

Stay active, stay healthy with Dr. Joints Advanced

Brand IP Statement(s) re: (c), (TM), (SM)

Calcium Fructoborate (Fruitex-B) is a registered trademark of VDF FutureCeuticals, Inc. manufactured under US Patent #5,962,049.