Ultra Lipoic®

Other Combinations

Brand: Natures Plus

Tablet or PillOther CombinationsOff Market
Click to view full label

Net Contents

30 Bilayered Tablet(s)

Serving Size

1 Bilayered Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

0 97467 05220 8

Product Version

PRODUCT NO. 5220 IFC. 1136653

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

5Active Ingredients

5 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Bilayered Tablet(s) · 1 per day

IngredientAmount Per Serving
Alpha Lipoic Acid500 mg—
R-Lipoic Acid100 mg—
Proprietary Anti-Aging Whole Food Complex50 mg—
MSM——
NAC——
Turmeric(Curcumin)——
Grape (Vitis vinifera) seed extract(Proanthocyanidins)——
Proprietary Anti-Aging Probiotic Complex50 mg—
Lactobacillus acidophilus——
L. sporogenes(B. coagulans)——
Streptococcus thermophilus——
Full Spectrum Whole Food Blend50 mg—
Energizing & Cleansing Green Whole Food Blend——
Strength & Endurance White Whole Food Blend——
Defense & Repair Yellow Whole Food Blend——
Brain Support Blue Whole Food Blend——
Anti-Aging Red Whole Food Blend——

Not Present

Other Ingredients

Microcrystalline CelluloseHydroxypropyl MethylcelluloseVegetable CelluloseStearic AcidDi-Calcium PhosphateMagnesium StearatePharmaceutical Glaze

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, one tablet daily.

Warnings & Precautions

Precautions re: Children

Keep out of reach of children.

Storage

Storage

Keep tightly closed in a cool, dry place.

Formulation

Formula re: Contains

With Probiotics, Anti-Aging Nutrients and Full Spectrum Whole Foods

Formulation re: Does NOT Contain

Gluten free. Free from artificial colors and preservatives. Free from the common allergens yeast, wheat and soy.

Formula re: Contains

Nature’s Plus Ultra Lipoic delivers 500 mg of alpha lipoic acid, and an additional 100 mg of R-lipoic acid for total body antioxidant, anti-aging nutritional support. Alpha lipoic acid is the premier rejuvenating antioxidant for the widest range of tissues. Proven effective in “high-energy” tissues like the heart, brain, kidneys, nerves and muscles, as well as in “low-energy” tissues, such as blood cells, connective tissues and endothelium, alpha lipoic acid is a well-rounded whole-body antioxidant.

Formula re: Contains

But Nature’s Plus takes lipoic acid supplementation to a whole new level with an additional 100 mg of R-lipoic acid for even greater support of high-energy tissues. Cells that need more energy make far better use of R-lipoic than any other form. R-lipoic is the form that targets free radicals in those tissues (heart, brain, kidneys, nerves and muscles), helping them function more cleanly and efficiently. The extra 100 mg of R-lipoic antioxidant power in Nature’s Plus Ultra Lipoic yields an unmistakable sensation of vitality that no other lipoic acid supplement can match.

Formula re: Contains

For even greater synergistic activity, Nature’s Plus Ultra Lipoic further supplies Lactobacillus acidophilus and other healthful probiotics, as well as time-honored, standardized botanical extracts and proprietary full spectrum whole food blends. Revolutionary bi-layered delivery provides rapid and extended lipoic acid support for total health.

FDA Statements

FDA Statement of Identity

Alpha Lipoic and R-Lipoic Acid Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

General Statements: All Other Content

Revolutionary bi-layer delivery system

General Statements: All Other Content

Nutritional Support for Overall Well-Being.

Brand IP Statement(s) re: (c), (TM), (SM)

Natural Organics

General Statements: All Other Content

Nature’s Plus Ultra Lipoic is your complete, energizing, rejuvenating antioxidant and anti-aging lipoic acid supplement!

General: Product/Version Code

PRODUCT NO. 5220 IFC. 1136653

Manufacturer & Distributor

Manufacturer

Natural Organics Laboratories, Inc. makers of Nature's Plus

9500 New Horizons Blvd., Amityville, New York, 11701, USA

Market Reference

$8.40 – $154.99· 11 listings
  • NaturesPlus Ultra Lipoic

    iHerb4.6(45)
    $32.26
  • Nature's Plus Organic Juice Ultra Tablets

    Walmart - Harvest Moon Natural Foods4.2(11)
    $29.97
  • Nature's Plus Ultra Probiotics Capsules

    Smallflower.com4.7(189)
    $20.49
  • NaturesPlus Ultra Juice Bi-Layered Tablets

    Instacart4.2(11)
    $28.49
  • Nature's Life Lipotropic Complex 90 Tablets

    iHerb4.8(54)
    $24.09
  • 3 x Ultra Pro Probiotic 30 capsules - Natures Plus

    Naturitas4.8(72)
    $130.89
  • Natural Factors R- Lipoic Acid 100 mg. 60 Vegetarian Capsules

    Target4.7(297)
    $21.99
  • Nature's Blend National Vitamin Company Nature Foots Blend Alpha Lipoic Acid Dietary Supplements

    Honest Medical
    $8.40Lowest

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • GNC

    3.4 (39)

    Vitamin & supplements store

    1801 Howell Mill Rd NW, Atlanta, GA 30318

  • Discount Nutrition

    4.8 (59)

    Vitamin & supplements store

    1544 Piedmont Rd NE Ste 318, Atlanta, GA 30324

  • Supplements With Science LLC - Corporate Headquarters

    4.9 (10)

    Vitamin & supplements store

    1100 Peachtree St NE Suite 200, Atlanta, GA 30309

  • The Vitamin Shoppe

    4.3 (156)

    Vitamin & supplements store

    3261 Peachtree Rd, Atlanta, GA 30305

  • Total Nutrition Atlanta

    4.8 (173)

    Vitamin & supplements store

    6597-G Roswell Rd NE, Sandy Springs, GA 30328

  • Good Nutrition

    4.5 (117)

    Vitamin & supplements store

    2855 N Druid Hills Rd NE, Atlanta, GA 30329

  • GNC

    3.6 (56)

    Vitamin & supplements store

    650 Ponce De Leon Ave NE #640-A, Atlanta, GA 30308

  • The Vitamin Shoppe

    3.9 (211)

    Vitamin & supplements store

    1209 Caroline St NE, Atlanta, GA 30307

Research & Studies

  • Clinically effective molecules of natural origin for obesity prevention or treatment

    GM Hidalgo-Lozada, A Villarruel-López… - International Journal of …, 2024 - mdpi.com

    … This review provides a comprehensive view of nature-based therapeutic options to address the increasing prevalence of obesity. It offers a valuable perspective for future research and …

    202418 citations
  • Exploring the Pharmacotherapeutic Potential of Natural Compound Alpha Lipoic Acid

    A Udaipurwala, P Pimple… - The Natural Products …, 2025 - benthamdirect.com

    … in obesity, improves endothelial function in cardiovascular health, and protects against neurodegenerative diseases in neurological health. These diverse effects illustrate that ALA …

    20252 citations
  • Alpha-lipoic acid: biological mechanisms and health benefits

    F Superti, R Russo - Antioxidants, 2024 - mdpi.com

    Alpha-lipoic acid (ALA) is a bioactive molecule with significant health effects. The biological action of ALA has been ascribed to the characteristic antioxidant properties of the oxidized …

    2024133 citations
  • Lipoic acid functions in Paneth cells to prevent human intestinal stem cell aging

    Z Zhang, Q Wan, Y Zhu, J Ye, F Fu, X Fan… - Nature …, 2025 - nature.com

    … Here, we find that the synthesis of α-lipoic acid (ALA) is reduced in old human small intestine. Notably, ALA supplementation inhibits ISC aging and decreases the number of atypical …

    202511 citations
  • Lipoic acid: its antioxidant and anti-inflammatory role and clinical applications

    F Andrea Moura, K Queiroz de Andrade… - Current topics in …, 2015 - benthamdirect.com

    … clinical trials to guide health professionals regarding the safety of prescription of this supplement. … This information is particurly important in view of the chemical natures of LA and DHLA …

    2015240 citations
  • Dietary alpha-lipoic acid alleviates heat stress by modulating insulin-like signaling to maintain homeostasis in C. elegans

    L You, Z Huang, W He, L Zhang, H Yu, Y Zeng… - Food & Function, 2025 - pubs.rsc.org

    … Prolonged exposure to high temperatures can cause oxidative stress in the body, negatively impacting human health. Alpha-lipoic acid (ALA) is a naturally occurring antioxidant …

    20254 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-02-25. DSLD Label ID: 188816. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.