Methyl Combo®

Vitamins

Brand: Nature's Sunshine

CapsuleVitaminOff Market
Click to view full label

Net Contents

60 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

60

Supplement Form

Capsule

Bar Code (UPC/SKU)

0 99904 21689 1

Product Version

Stock No. 21689

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

2Active Ingredients

2 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2% Daily Value Coverage

2 ingredients report a %DV; 2 meet or exceed 100% DV.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Capsule(s) · 2 per day

IngredientAmount Per Serving% Daily Value
Folate(Methyltetrahydrofolate Calcium Salt)1333 mcg DFE333%
Vitamin B12(Methylcobalamin)1000 mcg41667%

Not Present

Other Ingredients

CelluloseDicalcium PhosphateCapsuleMagnesium StearateSilicon Dioxide

Target Groups

Adult (18 - 50 Years)

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Recommendation Take 1 capsule twice daily, or as directed by your healthcare practitioner.

Warnings & Precautions

Precautions re: All Other

Warnings: Consult your medical provider before use if you have any medical conditions or concerns. This bottle was sealed for your protection. Do not use if inner seal is missing or damaged.

Formulation

Formula re: Contains

Methyl Combo is a powerful blend of Methyl B12 and Methyl Folate that was designed using the most biologically active forms of these key nutrients.

Formula re: Contains

Methyl B12 & Methyl Folate combination

Formula re: Contains

Dietary Folate Equivalent (DFE). 1333 DFE is equivalent to 800 mcg of Folic Acid.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

010216890117

General Statements: All Other Content

These essential vitamins support the nervous system, and overall well-being, and they assist those suffering from situational emotional stress.

General Statements: All Other Content

Nature's Sunshine uses natural source materials that are subject to color variation. Product of U.S.A. New! Quality, service, integrity

General Statements: All Other Content

Contributes to the maintenance of normal neurological and psychological functions Contributes to a reduction of tiredness and fatigue

General Statements: All Other Content

Guaranteed pure

Manufacturer & Distributor

Manufacturer

Nature's Sunshine Products, Inc.

Spanish Fork, UT, 84660

1-800-223-8225

Market Reference

$23.14 – $379.00· 40 listings
  • Nature's Sunshine Methyl Combo 60 Capsules

    Institute of Natural Therapeutics
    $33.00
  • Nature's Sunshine Methyl B-12 Complete Liquid

    Nature's Sunshine Products
    $24.85
  • Nature's Sunshine Super Trio 60 Packets

    Nature's Sunshine Products
    $90.15
  • Nature's Sunshine Artemisia Combination 100 Caps

    Nature's Sunshine Products4.2(16)
    $30.45
  • Nature's Sunshine Multiple Time-Release Tablets

    Nature's Sunshine Products
    $43.00
  • Nature's Sunshine MSM 90 Tablets

    Nature's Sunshine Products5.0(8)
    $31.60
  • Nature's Sunshine Methyl B-12 Complete Liquid 2 fl. oz. | Promotes Energy Contributes to Nervous System Function Supports the Immune System and

    GoSupps.com
    $104.99
  • Nature's Sunshine Milk Thistle Combination 90 Tablets

    Nature's Sunshine Products4.5(2)
    $45.60

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Research & Studies

  • Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols

    V Nobile, A Michelotti, E Cestone, N Caturla… - Food & nutrition …, 2016 - Taylor & Francis

    … solution, 2) multiwell plates were incubated at 37C, using a microplate incubator/shaker under continuous agitation for 1 h, 3) after incubation 1.3 ml R1 solution (2.13 mg N-methyl-2-…

    2016100 citations
  • Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

    RA Koeth, Z Wang, BS Levison, JA Buffa, E Org… - Nature …, 2013 - meddean.luc.edu

    … to allow for microbial colonization (‘conventionalization’), previously germ-free mice acquired the capacity to produce both d3-(methyl)-TMA and d3-(methyl)-TMAO following oral d3-(…

    20135,538 citations
  • A pilot, four-week, dietary program with targeted nutraceuticals improves cardiometabolic functioning, metabolic transformation, and gut health

    W Gao, JJ Lamb, D Graham, B Manda… - Journal of Functional …, 2025 - Elsevier

    … Thirty-eight generally healthy overweight subjects were assigned a low-glycemic load, … supplementation and a physical activity regimen. Subjects expressed positive subjective health …

    2025
  • Fish oil supplementation: evidence for health benefits

    WS Harris - Cleveland Clinic journal of medicine, 2004 - cdn.mdedge.com

    … Fish oil supplements are available as a triglyceride-based form or as a methyl or ethyl ester form. Previous work in our laboratory showed that serum levels of EPA/DHA were raised …

    2004231 citations
  • Methyl jasmonate enhances antioxidant activity and flavonoid content in blackberries (Rubus sp.) and promotes antiproliferation of human cancer cells

    SY Wang, L Bowman, M Ding - Food Chemistry, 2008 - Elsevier

    The effects of preharvest methyl jasmonate (MJ) application on fruit quality, antioxidant activity and flavonoid content in blackberries (Rubus sp.) were determined. Anticancer activity …

    2008307 citations
  • Beneficial effects of betaine: a comprehensive review

    MK Arumugam, MC Paal, TM Donohue Jr, M Ganesan… - Biology, 2021 - mdpi.com

    … Betaine mainly functions as (i) an osmolyte and (ii) a methyl-group donor. This review describes the major physiological effects of betaine in whole-body health and its ability to protect …

    2021347 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-10-23. DSLD Label ID: 208564. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.