Indole-3-Carbinol®

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Serving Size: 2 Capsule(s) · 1 per day

Not Present

• 

  Nature's Sunshine Indole 3 Carbinol 60 Capsules

  Nature's Sunshine Products5.0(11)

  $58.55
• 

  Nature's Three

  CaringSunshine.com5.0(1)

  $47.65
• 

  NOW Indole 3 Carbinol

  Target4.8(3700)

  $20.99Lowest
• 

  Indole-3-carbinol

  aobious.com

  $25.00
• 

  Life Extension Indole 3-Carbinol with DIM Capsules

  Life Extension4.4(8)

  $24.99
• 

  Indole-3-carbinol 400mg 120 Vegeterian Capsules for Hormone Balance & Cellular Health

  Walmart - LongLifeNutri

  $29.30
• 

  Nature's Sunshine AnxiousLess 30 Capsules

  CaringSunshine.com4.1(7)

  $48.70
• 

  Nature's Sunshine Grapine High Potency 60 Tablets

  Nature's Sunshine Products

  $65.25

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• Holly Hill Health Foods, Inc.

  4.7 (160)

  Vitamin & supplements store

  1200 Welsh Rd Ste N, North Wales, PA 19454

  Directions(215) 361-7770

• Willner Chemists

  4.7 (146)

  Vitamin & supplements store

  100 Park Ave, New York, NY 10017

  Directions(800) 633-1106

• National Nutrition

  4.8 (1263)

  Vitamin & supplements store

  5 Progress Dr, Orillia, ON L3V 0T7, Canada

  Directions(800) 526-9772

• SameDaySupplements.com

  4.5 (503)

  Vitamin & supplements store

  64 Nancy St Unit c, West Babylon, NY 11704

  Directions(631) 539-7339

• The Road Less Traveled

  4.8 (12)

  Vitamin & supplements store

  312 Guilbeau Rd, Lafayette, LA 70506

  Directions(337) 988-9889

• Nutriessential

  2.0 (16)

  Vitamin & supplements store

  5880 Collins Ave, Miami Beach, FL 33140

  Directions(786) 623-4117

• The Vitamin Shop

  4.6 (212)

  Vitamin & supplements store

  1212 Broad St, Victoria, BC V8W 2A5, Canada

  Directions+1 250-386-1212

• Professional Supplement Center

  3.9 (73)

  Vitamin & supplements store

  5525 Palmer Crossing Cir, Sarasota, FL 34233

  Directions(941) 487-5990

• A microbiota and dietary metabolite integrates DNA repair and cell death to regulate embryo viability and aneuploidy during aging

  R Sonowal, AI Swimm, F Cingolani, N Parulekar… - Science …, 2023 - science.org

  … or introduced as dietary supplements may promote extended periods of health, motility, and … Indole-3-carbinol, an indole derivative commonly found in cruciferous vegetables, exhibits …

  202314 citations

• Indole-3-carbinol: occurrence, health-beneficial properties, and cellular/molecular mechanisms

  D Amarakoon, WJ Lee, G Tamia… - Annual Review of Food …, 2023 - annualreviews.org

  … Hydrolysis of glucobrassicin by plant or bacterial myrosinase produces multiple indoles, predominantly indole-3-carbinol (I3C). Findings from preclinical models indicate that both I3C …

  202375 citations

• Modulation of gut microbiota, up-regulation of ZO-1, and promotion of metabolism as therapeutic mechanisms of indole-3-carbinol against obesity in mice

  XW Mao, G Paerhati, Y Wu, LF Cheng - Frontiers in Pharmacology, 2025 - frontiersin.org

  … Background: Indole-3-carbinol (I3C) is a compound derived from Cruciferous vegetables. … for maintaining overall health and preventing and treating various diseases. By supplementing …

  202514 citations

• Plant-derived indole alkaloids in chronic inflammatory diseases: molecular mechanisms, therapeutic potential and translational challenges

  MJ Kapil, M Basak, KN Dutta, BJ Sahariah… - …, 2026 - Springer

  … Background Chronic inflammatory diseases are major global health challenges driven by … other indole alkaloids, including isorhynchophylline and indole-3-carbinol, which also signify a …

  2026

• Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

  C Hammerschmidt-Kamper, D Biljes, K Merches… - PLoS …, 2017 - journals.plos.org

  … supplements in an uncontrolled market. We therefore sought to investigate how oral dosing of one such AhR-ligand, indole-3-carbinol (… health effects of this important plant compound. …

  201746 citations

• Potential dietary and therapeutic strategies involving indole-3-carbinole in preclinical models of intestinal inflammation

  A Qazi, S Comiskey, N Calzadilla, F Amin, A Sharma… - Nutrients, 2023 - mdpi.com

  Diet–microbiota interactions are emerging as important contributors in the pathogenesis of inflammatory bowel diseases (IBD), characterized by chronic inflammation of the GI tract. The …

  202311 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-05-22. DSLD Label ID: 220909. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.