Net Contents
36 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
Not specified
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 31604 41107 7
Product Version
Not specified
Suggested Use
Suggested use: Start with 1 tablet per day. For easier swallowing; take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal.If benefits are not achieved within two weeks; you may require a higher level of supplementation. To determine the proper level of supplementation that works for you; gradually increase the number of tablet (maximum 1600 mg/day) until benefits are achieved.
Market Reference
Nature Made SAM-e Complete 400 mg
Walmart - Mayrip LLC4.6(190)$52.98Nature Made Natural Plant Sourced Softgels
Target4.7(594)$21.78LowestWalgreens Sam-e 400 mg Coated Caplets
Walgreens.com$49.99Nature Made 400,IU Softgels (Pack of 2)
Walmart - Pharma Frills4.7(594)$25.41Sam-E, 400mg, Complete Ds Value, 36 Tablets
Med-Vet International$62.60Nature Made Vitamin E 400 Iu 350 Softgels Antioxidant Ct 2 Pack Total
eBay4.7(74)$54.99SAM-e 400mg
Pure Prescriptions4.7(430)$58.99Sam-e 400mg 120 Enteric Coated Caplets (2 Boxes Of 60) - Vegan,
eBay - 123christina0_64.3(32)$112.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.6 (269)Vitamin & supplements store
3807 E Colonial Dr, Orlando, FL 32803
The B-12 Store at Florida Mall
4.8 (24)Vitamin & supplements store
8001 S Orange Blossom Trl Ste. 548, Orlando, FL 32809
Nature's Dynamics
4.9 (103)Vitamin & supplements store
3802 Silver Star Rd, Orlando, FL 32808
GNC
4.7 (152)Vitamin & supplements store
4967 International Dr Ste 3A.33, Orlando, FL 32819
The Vitamin Shoppe
4.4 (184)Vitamin & supplements store
4012 Eastgate Dr, Orlando, FL 32839
GNC
4.3 (66)Vitamin & supplements store
4014 S Semoran Blvd, Orlando, FL 32822
GNC
4.4 (77)Vitamin & supplements store
2875 S Orange Ave Ste 5, Orlando, FL 32806
The Vitamin Shoppe
4.5 (275)Vitamin & supplements store
3312 Greenwald Way N, Kissimmee, FL 34741
Research & Studies
… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… event profile similar to the SAM-e Complete™ comparator product. The relative bioavailability of MSI-195 was approximately 2.8-fold higher than SAM-e Complete based on area under …
202014 citationsS-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… 400 mg once or twice daily, 400 mg daily titrated to 800 mg twice daily for ADHD, and 400 mg daily titrated to 800 mg … For depression, SAMe was dosed between 200 and 3200 mg daily, …
202410 citationsNutritional Supplements and PTSD.
CD Townsend - … Perspectives: Journal of the Council on …, 2018 - search.ebscohost.com
… SAM-e also helps with healthy nerve … mg twice daily, for the first day, then increase to 400 mg twice daily on day three, then to 400mg three times daily on day 10, and finally to the full …
2018Ease aching joints: natural supplements can help reduce inflammation, build cartilage, and help repair damaged joints.
B Kallen - Natural Health, 2008 - go.gale.com
… by Nature Made or Life Extension, brands that test for potency. Dosage: The current recommended intake is 400 … Some doctors suggest taking B-vitamins with SAM-e, since large …
2008Utility of nutraceutical products marketed for cognitive and memory enhancement
GJ McDougall Jr, V Austin-Wells… - Journal of Holistic …, 2005 - journals.sagepub.com
… nutraceuticals, medical and allied health care professionals … Sam-e is a shortening of the technical name and is trademarked under this name. Sam-e is used as a nutritional supplement …
200519 citationsEvidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
GI Papakostas - Journal of Clinical Psychiatry, 2009 - psychiatrist.com
… increasingly interested in nonpharmaceutical supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-l-methionine (SAM-e), a naturally …
2009178 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2018-07-25. DSLD Label ID: 179341. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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