SAM-e Complete®
Non-Nutrient / Non-BotanicalBrand: Nature Made
Net Contents
24 Enteric Coated Tablet(s)
Serving Size
2 Tablet(s)
Servings Per Container
12
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 31604 01091 1
Product Version
List No: 1091S P303 Cat: A301 1A146
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 2 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAM-e | 400 mg | — |
Not Present
Other Ingredients
Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
SUGGESTED USE: Start with taking 2 tablets per day. The best time to take SAME-e is on an empty stomach at least 30 minutes before a meal. Clinical studies indicate that benefits are most likely evident after 7-14 days of supplementation. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1600 mg/day) until benefits are achieved.
Warnings & Precautions
Precautions re: All Other
CAUTION: Foil blister pack ensures safety and freshness. Do not use if tamper evident printed foil seal over tablets is broken.
Precautions re: Children
Store in a cool, dry place, out of reach of children.
Precautions re: All Other
People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervisions.
Precautions re: Pregnant or Nursing or Prescription Medications
If you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before using this product.
Storage
Storage
Store in a cool, dry place, out of reach of children.
Formulation
Formulation re: Does NOT Contain
This product is gluten and yeast free.
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
dietary supplement
Other Label Statements
General Statements: All Other Content
Naturally restores a healthy mood When your emotions are healthy & balanced, you feel like yourself. Everyday tasks seem easy and you feel like you are in control. However, sometimes emotions can get out of balance, causing you to feel moody. What most people don't know is this imbalance can be associated with low levels of SAM-e {S-adenosylmethionine), a naturally occurring molecule produced by your body. SAM-e helps to maintain healthy emotions, but your SAM-e levels can run low due to various factors such as diet and aging.
Brand IP Statement(s) re: (c), (TM), (SM)
Now you can replenish your SAM-e levels by taking Nature Made SAM-e Complete(R).
General Statements: All Other Content
Lot.: Exp.:
General Statements: All Other Content
SAM-e has been proven to restore a healthy mind in as little as 7-14 days when taken daily. Promotes joint health Because SAM-e is naturally produced in your body, it also has other vital functions aside from helping to maintain healthy emotions. One of these other functions is to promote joint health, which naturally deteriorates with physical activity and age.
General Statements: All Other Content
For more information, please visit www.SAM-e.com
General Statements: All Other Content
SAM-e is a moisture sensitive product. That is why at Nature Made, we use foil blister packaging to ensure that each tablet of our SAM-e Complete is fresh and safe when you take it.
General Statements: All Other Content
Enter Code for Wellness Rewards Points at www.NatureMade.com
General Statements: All Other Content
Complete because SAM-e has been clinically proven to benefit body functions including mood support & joint comfort. #1 Brand of SAM-e supplements based on POS scan data at Food, Drug, Mass and Club.
General Statements: All Other Content
100% money back Results guaranteed or your money back. Visit NatureMade.com/guarantee for details.
General Statements: All Other Content
CLINICALLY PROVEN FOR HEALTHY MOOD & JOINT COMFORT NATURALLY RESTORES A Healthy Mood
General Statements: All Other Content
#1 SAM-e BRAND
General: Product/Version Code
List No: 1091S P303 Cat: A301 1A146
General Statements: All Other Content
Valid only for U.S. and Puerto Rico residents.
Brand IP Statement(s) re: (c), (TM), (SM)
SAM-e Complete(R) tablets are made to Nature Made's guaranteed purity and potency standards.
Manufacturer & Distributor
Distributor
Nature Made Nutritional Products
Mission Hills, CA, 91346-9606, U.S.A.
1-800-276-2878
Market Reference
Nature Made SAM-e Complete 400 mg
Nature Made4.5(310)$62.19Nature Made Sam E 200 mg 24 ct
mondialpharma.com$102.27Nature Made Multi Complete Tablets
Food Depot4.5(516)$10.91Nature Made Vitamin E
Nature Made4.7(170)$18.29Nature Made Vitamin E 400 IU Softgels
Nature Made4.7(270)$18.89Nature Made Multi Complete Tablets 130 ea (Pack of 2)
Walmart - Pharma Frills2.7(12)$31.06Sam-E, 400mg, Complete Ds Value, 36 Tablets
Med-Vet International$62.60SAM-E 200mg Tablets (30 Tabs)
Zen Supplements$34.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Master of Nutrition
4.6 (112)Vitamin & Supplements Shop
110 Bordesley Grn, Birmingham B9 4TS
Sam's Health UK
5.0 (5)Vitamin & Supplements Shop
47 sturge close, Birmingham B29 6GG
PHILOSOFIT SPORTS & NUTRITION
5.0 (51)Vitamin & Supplements Shop
891b Washwood Heath Rd, Ward End, Birmingham B8 2NA
Elite sports nutrition
5.0 (11)Vitamin & Supplements Shop
Chelmsley Woods Centre, 20 Greenwood Wy, Birmingham B37 5TL
Body Mania
4.7 (179)Vitamin & Supplements Shop
328 Slade Rd, Birmingham B23 7LP
Europe Nutrition Supplements
4.5 (2)Sports Nutrition Shop
Northwood St, Birmingham HA6 3XL
Active Nutrition
5.0 (21)Vitamin & Supplements Shop
2168 Coventry Rd, Sheldon, Birmingham B26 3JB
Starplus Vitamins Ltd
3.5 (2)Vitamin & Supplements Shop
Kings Rd, Tyseley, Birmingham B11 2AL
Research & Studies
… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… event profile similar to the SAM-e Complete™ comparator product. The relative bioavailability of MSI-195 was approximately 2.8-fold higher than SAM-e Complete based on area under …
202014 citationsThe SAM-e Solution: The Essential Guide to the Revolutionary Antidepression Supplement
D Mitchell - 2000 - books.google.com
… During the course of their research, investigators have found that low SAM-e levels are characteristic of many different medical conditions, which are discussed at length in this book. …
20004 citationsThe Methylation Miracle: Unleashing Your Body's Natural Source of SAM-e
P Frankel, N Bruning - 1999 - books.google.com
… the right foods and nutritional supplements to protect our health. Likewise, Nancy Bruning brings her extensive experience in making important health issues accessible to the general …
19994 citationsEase aching joints: natural supplements can help reduce inflammation, build cartilage, and help repair damaged joints.
B Kallen - Natural Health, 2008 - go.gale.com
… by Nature Made … SAM-e, also valued for its antidepressant properties, may cause mood changes related to an increase in serotonin. Some doctors suggest taking B-vitamins with SAM-e…
2008S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… in full compliance (see PRISMA Checklist in the Supplementary Materials for full details) [11]. … materials used in this review can be made available upon request. No amendments were …
202410 citationsTreatment of mood and depressive disorders with complementary and alternative medicine: efficacy review
JBR Cutler, O Pane, SK Panesar… - … & Women's Health, 2023 - Wiley Online Library
… in the presence of SAM-e. The most common adverse effects of SAM-e are gasftrointestinal, such as … This review also indicated that SAM-e was more effective than placebo in reducing …
202317 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-10-25. DSLD Label ID: 26628. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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