Brand: Nature Made

Tablet or PillOff Market
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Net Contents

24 Enteric Coated Tablet(s); 200 mg

Serving Size

2 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

0 31604 01091 1

Product Version

Not specified

Suggested Use

SUGGESTED USE: Start with taking 2 tablets per day. The best time to take SAME-e is on an empty stomach at least 30 minutes before a meal. Clinical studies indicate that benefits are most likely evident after 7-14 days of supplementation. If benefits are not achieved within two weeks; you may require a higher level of supplementation. To determine the proper level of supplementation that works for you; gradually increase the number of tablets (maximum 1600 mg/day) until benefits are achieved.

Market Reference

$4.99 – $437.27· 25 listings
  • Nature Made SAM-e Complete 400 mg

    Nature Made4.5(45)
    $62.19
  • Nature Made SAM-e 200 mg Complete Tablets

    Instacart
    $4.99Lowest
  • Nature Made Multi Complete Tablets

    Fleet Farm4.5(458)
    $13.79
  • Nature Made Vitamin E

    Walgreens.com4.7(594)
    $29.99
  • Nature's Craft SAM-e Capsules

    iHerb4.8(361)
    $24.99
  • Nature Made Multi Complete Tablets 130 ea (Pack of 5)

    Walmart - Pharma Frills4.5(458)
    $69.54
  • Nature Made Multi Complete Softgels

    Instacart5.0(8)
    $11.49
  • Nature Made Adult Multivitamin + Omega-3 Dietary Supplement

    CVS Pharmacy4.7(157)
    $20.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Supplement World

    4.9 (338)

    Vitamin & supplements store

    6370 E Central Ave, Wichita, KS 67208

  • Supplement Giant

    4.7 (33)

    Vitamin & supplements store

    1821 E Madison Ave #1100, Derby, KS 67037

  • TransformX Supplements

    5.0 (15)

    Vitamin & supplements store

    135 N Main St Ste e, El Dorado, KS 67042

  • GNC

    3.5 (13)

    Vitamin & supplements store

    1942 N Rock Rd Ste 700, Derby, KS 67037

  • Protein Pantry

    4.9 (14)

    Weight loss service

    Air Capital Flight Line, 4174 S Oliver St Building 174 - H, Wichita, KS 67210

  • Supplement World

    4.9 (142)

    Vitamin & supplements store

    1535 s Oliver, Wichita, KS 67218

  • Supplement Giant

    4.8 (192)

    Vitamin & supplements store

    2260 N Rock Rd, Wichita, KS 67226

  • Supplement World

    4.9 (152)

    Vitamin & supplements store

    7700 E Kellogg Dr Ste q01d, Wichita, KS 67207

Research & Studies

  • A pilot study of S-adenosylmethionine in treatment of functional abdominal pain in children.

    LJ Choi, JS Huang - Alternative Therapies in Health & …, 2013 - search.ebscohost.com

    … Currently, medical practitioners widely use tricyclic … S-adenosylmethionine (SAM-e) is a dietary supplement that … All participants received oral SAM-e (Nature Made, Pharmavite; Mission …

    201312 citations
  • S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review

    KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com

    … in full compliance (see PRISMA Checklist in the Supplementary Materials for full details) [11]. … materials used in this review can be made available upon request. No amendments were …

    202410 citations
  • Overview of Complementary, Alternative, and Integrative Approaches

    RA OWENS - … and Alternative Approaches Across the Life Span, 2022 - books.google.com

    … If public health concerns arise about a dietary supplement after … SAM-e may increase the production of serotonin and … Lower levels of SAM-e have been reported in cerebrospinal fluid …

    20221 citations
  • The Therapeutic benefits of S-adynosylmethionine for Depression, Osteoarthritis and Longevity: A Literature

    M Goodrich - 2011 - logan.edu

    … of SAM-e as well as comparing supplementation of SAM-e to … Finally, recommendations for usage and benefits will be made … after the Dietary Supplement Health and Education Act was …

    2011
  • SAM-e may also improve sexual dysfunction in men

    R Olivier - Original Internist - researchgate.net

    … Oral consumption of SAM-e has been recognized for its beneficial effects in osteoarthritis. 6 SAM-e intake … and the other nutrients discussed above provides support for numerous health …

  • Canadian network for mood and anxiety treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 5 …

    AV Ravindran, LG Balneaves, G Faulkner, A Ortiz… - Focus, 2018 - psychiatryonline.org

    … SAM-e is a natural substrate in the human body, including in the brain, that is thought to … -3 fatty acids, SAM-e, and SD can be considered. Other physical and natural health products are …

    201833 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-10-25. DSLD Label ID: 26628. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.