SAM-e Complete 200 mg®
Other CombinationsBrand: Nature Made
Functions
Net Contents
24 Enteric Coated Tablet(s)
Serving Size
2 Tablet(s)
Servings Per Container
12
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 31604 01091 1
Product Version
List No: 1091S P200 Cat: A851 1A146
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
2 distinct active ingredients are disclosed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 2 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| Protein | < 1 Gram(s) | — |
| SAM-e | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested use: Start with 2 tablets per day. For easier swallowing, take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1600 mg/day) until benefits are achieved.
Warnings & Precautions
Precautions re: All Other
Foil blister pack ensures safety and freshness. Do not use if tamper evident printed foil seal over tablets is broken.
Precautions re: Children
Store in a cool, dry place, out of reach of children.
Precautions re: All Other
Caution: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision.
Precautions re: Pregnant or Nursing or Prescription Medications
If you are pregnant or nursing, or taking prescription medications, including antidepressants, consult your doctor before using this product.
Storage
Storage
Store in a cool, dry place, out of reach of children.
Formulation
Formulation re: Does NOT Contain
This product is gluten free.
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
From the #1 pharmacist recommended mood health supplement brand, Nature Made SAM-e helps support a healthy mood.
General Statements: All Other Content
When your emotions are healthy & balanced, you feel like yourself. However, sometimes emotions can get out of balance, causing you to feel moody. This imbalance can be associated with low levels of SAM-e (S-adenosylmethionine), a naturally occurring molecule produced by the body. SAM-e levels can run low due to various factors such as diet and aging. Mood improvement Days Replenish your SAM-e levels and feel the difference in as little as 7-14 days when taken daily. Helps support joint comfort Nature Made SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue. 100% money back 100% money back guarantee Visit NatureMade.com/guarantee for details. Nature Made St. John's Wart is the #1 pharmacist recommended mood health supplement followed by Nature Made SAM-E based on the U.S. News & World Report - Pharmacy Time Survery
General Statements: All Other Content
SAM-e is a moisture sensitive product. That is why at Nature Made, we use foil blister packaging to ensure that each tablet of our SAM-e Complete is fresh and safe when you take it.
General Statements: All Other Content
Restores a healthy mood in as little as 7-14 days when taken daily Complete studies have shown that SAM-e helps support a healthy mood & joint comfort
General Statements: All Other Content
Money back guarantee Helps support a healthy mood & joint comfort Clinically studied ingredient
General: Product/Version Code
List No: 1091S P200 Cat: A851 1A146
Brand IP Statement(s) re: (c), (TM), (SM)
SAM-e Complete tablets are made to Nature Made's guaranteed purity and potency standards.
Manufacturer & Distributor
Distributor
Nature Made Nutritional Products
Mission Hills, CA, 91346-9606, U.S.A.
1-800-276-2878
Market Reference
Nature Made SAM-e Complete 400 mg
Nature Made4.5(45)$62.19
Nature Made SAM-e 200 mg Complete Tablets
Instacart$4.99Lowest
Nature's Craft SAM-e 200 mg Capsules
Target4.8(269)$20.15
Nature's Sunshine SAM-e 200 Mg 30 Tablets
Nature's Sunshine Products5.0(1)$75.05
Natural Factors SAMe 200 mg
Target4.8(144)$20.99
SAM-E 200mg Tablets (30 Tabs)
McGuff Medical Products$22.75
SAM-E 200 mg 60 Capsules
Physicians Preference Vitamins$84.50
Sam-e 200 200mg
Pure Prescriptions4.6(438)$55.99
Where to Buy Locally
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GNC
4.2 (15)Vitamin & supplements store
4871 Fort Campbell Blvd Ste c, Hopkinsville, KY 42240
Research & Studies
A pilot study of S-adenosylmethionine in treatment of functional abdominal pain in children.
LJ Choi, JS Huang - Alternative Therapies in Health & …, 2013 - search.ebscohost.com
… received SAM-e at an initial dose of 200 mg/d, with escalation to a maximum dose of 1400 mg… All participants received oral SAM-e (Nature Made, Pharmavite; Mission Hills, CA, USA), at …
201312 citationsSAMe (S-adenosylmethionine)
JC Echols, U Naidoo, C Salzman - Harvard Review of Psychiatry, 2000 - Taylor & Francis
… that the preparation promotes “joint health” and “emotional well-being.” … A box of 20 200-mg SAMe tablets carrying the Nature Made (Pharmavite… were withdrawn from 200 mg/day IV or …
200040 citationsS-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… depressive symptoms were seen ranging from 200 mg to 3200 mg. Many studies started at … doses starting at 200 mg to 800 mg for mild–moderate depression and 800 mg daily in one to …
202410 citations… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… event profile similar to the SAM-e Complete™ comparator product. The relative bioavailability of MSI-195 was approximately 2.8-fold higher than SAM-e Complete based on area under …
202014 citationsUtility of nutraceutical products marketed for cognitive and memory enhancement
GJ McDougall Jr, V Austin-Wells… - Journal of Holistic …, 2005 - journals.sagepub.com
… With the increased interest in nutraceuticals, medical and allied health care … Sam-e is used as a nutritional supplement in the treatment of AIDS-… S-adenosyl methionine 200 mg …
200519 citationsNutritional Supplements and PTSD.
CD Townsend - … Perspectives: Journal of the Council on …, 2018 - search.ebscohost.com
… SAM-e also helps with healthy nerve conduction as well. It … of 200 mg twice daily, for the first day, then increase to 400 mg … day 10, and finally to the full dose of 400 mg four times daily.…
2018
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2018-07-25. DSLD Label ID: 179333. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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